QUESTIONS AND CORRECT ANSWERS
What is chemotherapy? - CORRECT ANSWER Chemotherapy is the use of anticancer
(cytotoxic) drugs or hormonal agents to cure, palliate, maintain remission, or as a prophylatic
measure.
Chemotherapy is considered a "systemic treatment," what does this mean? - CORRECT
ANSWER Systemic treatment can reach metastatic and sanctuary sites not always treatable
with other modalities.
Who is responsible for prescribing and supervising chemotherapy? - CORRECT
ANSWER Medical Oncologists
Why is chemotherapy used? - CORRECT ANSWER To treat cells that have escaped from the
original cancer
To eliminate all cancer cells in the body
To prolong life by controlling cancer growth
To relieve symptoms and enhance QOL
How does chemotherapy work? - CORRECT ANSWER Chemotherapy works by killing
rapidly dividing cells.
The effectiveness of chemotherapy is influenced by what factors? - CORRECT
ANSWER Tumor cell burden
Growth rate of the tumor
Vascular supply
, Patterns of cell division
Concentration of drug made available to malig. cells
Concomitant - CORRECT ANSWER Two types of treatment take place at the same time
Extravasation - CORRECT ANSWER Accidental leakage from an IV into surrounding tissues
Neoadjuvent - CORRECT ANSWER Used to reduce tumor size BEFORE surgery/radiation
Adjuvent - CORRECT ANSWER Given AFTER radiation/surgery to eliminate remaining
cancer cells
What are the common methods for chemo administration? - CORRECT
ANSWER Intravenously
Orally
What are the benefits of combination chemotherapy? - CORRECT ANSWER Helps reduce the
risk of cancer developing resistance to one particular drug
Allows for different drugs to impact the cell during different phases of the cell cycle
Ex. MOPP (Hodgkin's)
Radiosensitizer - CORRECT ANSWER Works to increase the effects of radiation therapy
Ex. Doxirubicin
Radioprotectors - CORRECT ANSWER Works to limit the effects of radiation, decreasing
treatment side effects