Chapter 2
I. Digestion
A. Movement of food through the digestive tract
-Mouth to anus. Muscular methods: chewing, stomach churns, peristalsis (moves
through intestinal tract. Chemical: mastication, pepsin, hydrochloric acid, mucus
protects walls of stomach from stomach acid, end products: glucose, fatty acids,
amino acids
1. Muscular
a. Mouth – mastication
b. Esophagus –
(1) Upper esophageal sphincter (UES)
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(2) Lower esophageal sphincter (LES)
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c. Stomach
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(1) Kneading and churning
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d. Small intestine
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(1) peristalsis
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e. End Products of Digestion
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(1) Review Tables 2-2 & 2-3 on page 35
2. Chemical
a. Mouth
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(1) Salivary amylase
aC s
(2) Saliva
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(3) Mucous
b. Stomach
(1) hydrochloric acid: Stomach acid
(2) Mucus: Protects stomach from hydrochloric acids
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(3) Enzymes
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c. Small intestine: Nutrient absorption
(1) Enzymes
(2) Mucus
(3) Hormones
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(4) Bile
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(a) Emulsifies fat
(b) Produced by the liver and stored in the gallbladder.
II. Absorption
A. Small intestine
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1. Absorbs most of the nutrients
B. Large intestine
1. Primary task is the absorption of water (5 – 8 L/day)
2. Mineral absorption
(1) Sodium and other electrolytes
3. Vitamin absorption
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, Exam One Study Guide 2
(1) Vitamin K and biotin
4. Waste elimination
C. Lactose intolerance – inability to digest lactose
1. Intolerance varies by individual
2. Stems from a deficiency of the enzyme lactase
3. Not the same as a milk allergy
D. Prebiotics
1. Undigested carbohydrates that pass into the colon and ferment: causes good
bacteria
2. Stimulate the growth and activity of healthy bacteria
a. Increased immune function
b. Mineral absorption
c. Relieves constipation
d. Colon Cancer – may help destroy cancer cells and toxic enzymes
E. Probiotics
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1. Live microorganisms
a. In correct amounts may result in health benefits.
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2. Lactic – acid most common: muscles produce after working out
3. Clinical applications
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a. Diarrhea
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b. Inflammatory bowel disease
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c. Inhibition of H. Pylori: major cause of peptic ulcers
d. Lactose intolerance
III. Metabolism
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A. Carbohydrates
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1. Primary & preferred energy source
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a. Glucose: all carbs break down into glucose
(1) Metabolized by liver
(2) Hormonal control
(a) Insulin – only hormone that can lower blood glucose
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(b) Glucagon – one of the hormones that can elevate blood glucose
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(c) Steroids, epinephrine, thyroxine, somatostatin and growth hormone
can also elevate blood glucose.
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B. Lipids
1. Interrelated with glucose re: involve carbon, hydrogen and oxygen but in
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different amounts
2. Absorbed from small intestine and metabolized in liver (page 44)
C. Protein: same components as carbs and lipids but add nitrogen
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1. Balance between anabolism and catabolism
IV. Accessory Organs of Digestion
A. Pancreas, Liver, Gallbladder
Chapter 3
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