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ALU 201 Exam (Chapter 12) – Correct Solutions To All Questions

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ALU 201 Exam (Chapter 12) – Correct Solutions To All Questions

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ALU 201 Exam (Chapter 12) – Correct Solutions To
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Terms in this set (128)



hemophilia a caused by a deficiency of Factor VIII, is one of the
most commonly
discussed coagulation defects. It is an inherited
disorder with an X-linked recessive
inheritance pattern. This means that it is transmitted
on the X chromosome and only
exhibits the bleeding disorder trait when there is no
other normal X chromosome present.
This causes females to be the carriers while the
disease process develops predominantly
in males.


Christmas disease/Hemophilia B similar disorder caused by a lack of Factor IX.
Individuals with these disorders will have initial
platelet plug formation but lack the
ability to develop a fibrin clot. This leads to a delay of
several hours or days before a
bleeding episode begins


aplastic anemia replacement of hemopoietic tissue, depletion of cell
lines, reduction of hemopoietic tissue


polycythemia vera treatment can involve periodic phlebotomy


hemopoiesis the formation/production of blood cells in the living
body (especially in the bone marrow) The bone
marrow, one of the largest organs of the body,

,hemoglobin synthesis and The main function of the red blood cells is the
degradation transport of oxygen to the tissues, hemoglobin is the
carrier. Life span of rbc is 120 days. After degradation
it eventually becomes bilirubin.


cbc complete blood count. is the most useful lab tests for
evaluation of hematological processes & disorders.


hemoglobin The main component of erythrocytes. Serves as a
vehicle for oxygen & carbon dioxide transport.
Decreased values found in anemia, increased
amounts found in polycythemia, pulmonary disorders
& congestive heart failure


hematocrit Means to separate blood: It is the volume of
erythrocytes compared to the volume of whole
blood in a sample. Also called Packed cell volume.


platelet count blood test to determine the number of platelets in a
given volume of blood


megaloblastic anemia anemia characterized by many large immature and
dysfunctional red blood cells (megaloblasts) in the
bone marrow


aplastic anemia Is a bone marrow disorder characterized by a
reduction of hemopoietic tissue, depletion of cell
lines and reduction of hemopoietic tissue. Aplastic
anemia has a poor prognosis.


hemolytic anemias defined as a situation in which there is shortened red
blood cell survival. Anemia will develop if the rate of
cell production is not sufficient to compensate for
the decrease in cells resulting from excessive
destruction.


hereditary spherocytosis Is the mose common of hemolyic anemias : Often
called congenital hemolytic jaundice.It is a disease of
autosomal dominant inheritance.

, sickle cell disease the most common inherited disease of people in the
black population. caused by a substitution of an
amino acid in the hemoglobin protein of red blood
cells. when an individuals blood oxygen is low, the
cells turn
into rod shaped ones. clump and clog blood vessels.
It is important to establish the difference in Sickle cell
disease and sickle cell trait. People with the Trait do
not present extra risk provided they have not had any
crises.


polycythemia vera production of too many red blood cells by the bone
marrow. blood becomes too thick to easily flow
through the blood vessels can lead to thrombosis
with multiple systemic complications.30% of all
patients will develop leukemia. Management of
disorder requires periodically drawing off blood.


secondary polycythemia From other causes, usually due to lack of oxygen or
hormonal problems. This hypoxia can be caused by
respiratory disorders such as emphysema or by high
altitude.


polycythemia Means "Many Cells", a disorder characterized by an
abnormal increase in the number of red blood cells
in the blood. 3 types Polycythemia vera, seconary
polycythemia and relative polycythemia.


Five types of normal leukocytes neutrophils, eosinophils, basophils, lymphocytes,
monocytes


neutrophils the chief phagocytic leukocyte


eosinophils white blood cell that are responsible for combating
infection by parasites in vertebrates


basophils a type of WBC that promotes inflammation and
participates in allergic responses.

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