IMMUNITY: CASE STUDY EXAM
QUESTIONS AND ANSWERS (VERIFIED
AND UPDATED)
What is hypersensitivity? - ANS An exaggerated or inappropriate immune response that
causes tissue injury.
What are the two mechanisms of hypersensitivity? - ANS Antibody-mediated (Types I-III) and
Cell-mediated (T cell) (Type IV).
What characterizes Type I hypersensitivity? - ANS Immediate allergic response mediated by
IgE and mast cell degranulation.
What is the onset time for Type I hypersensitivity? - ANS Minutes.
Name two examples of Type I hypersensitivity. - ANS Allergic rhinitis and anaphylaxis.
What are the key players in Type I hypersensitivity? - ANS IgE, mast cells, eosinophils,
histamine.
@2026/2027 ALLRIGHTS RESERVED.
, What is the mechanism of Type II hypersensitivity? - ANS IgG or IgM antibodies bind to
antigens on cell surfaces, leading to cell lysis/phagocytosis.
What is the onset time for Type II hypersensitivity? - ANS Hours to days.
Provide an example of Type II hypersensitivity. - ANS Transfusion reactions.
What are the key players in Type II hypersensitivity? - ANS IgG, IgM, complement,
macrophages, NK cells.
What is the mechanism of Type III hypersensitivity? - ANS Antigen-antibody complexes form
in circulation, deposit in tissues, and activate complement, causing inflammation.
What is the onset time for Type III hypersensitivity? - ANS Hours to weeks.
Name an example of Type III hypersensitivity. - ANS Systemic lupus erythematosus (SLE).
What are the key players in Type III hypersensitivity? - ANS Antigen-antibody complexes,
complement, neutrophils.
What characterizes Type IV hypersensitivity? - ANS Delayed response mediated by T cells and
macrophages.
What is the onset time for Type IV hypersensitivity? - ANS 24-72 hours.
Provide an example of Type IV hypersensitivity. - ANS Contact dermatitis.
@2026/2027 ALLRIGHTS RESERVED.
QUESTIONS AND ANSWERS (VERIFIED
AND UPDATED)
What is hypersensitivity? - ANS An exaggerated or inappropriate immune response that
causes tissue injury.
What are the two mechanisms of hypersensitivity? - ANS Antibody-mediated (Types I-III) and
Cell-mediated (T cell) (Type IV).
What characterizes Type I hypersensitivity? - ANS Immediate allergic response mediated by
IgE and mast cell degranulation.
What is the onset time for Type I hypersensitivity? - ANS Minutes.
Name two examples of Type I hypersensitivity. - ANS Allergic rhinitis and anaphylaxis.
What are the key players in Type I hypersensitivity? - ANS IgE, mast cells, eosinophils,
histamine.
@2026/2027 ALLRIGHTS RESERVED.
, What is the mechanism of Type II hypersensitivity? - ANS IgG or IgM antibodies bind to
antigens on cell surfaces, leading to cell lysis/phagocytosis.
What is the onset time for Type II hypersensitivity? - ANS Hours to days.
Provide an example of Type II hypersensitivity. - ANS Transfusion reactions.
What are the key players in Type II hypersensitivity? - ANS IgG, IgM, complement,
macrophages, NK cells.
What is the mechanism of Type III hypersensitivity? - ANS Antigen-antibody complexes form
in circulation, deposit in tissues, and activate complement, causing inflammation.
What is the onset time for Type III hypersensitivity? - ANS Hours to weeks.
Name an example of Type III hypersensitivity. - ANS Systemic lupus erythematosus (SLE).
What are the key players in Type III hypersensitivity? - ANS Antigen-antibody complexes,
complement, neutrophils.
What characterizes Type IV hypersensitivity? - ANS Delayed response mediated by T cells and
macrophages.
What is the onset time for Type IV hypersensitivity? - ANS 24-72 hours.
Provide an example of Type IV hypersensitivity. - ANS Contact dermatitis.
@2026/2027 ALLRIGHTS RESERVED.
