PSYCHOPHARMACOLOGY: MOOD STABILIZERS, ANTIDEPRESSANTS, AND OPIOID REVERSAL AGENTS. EXAM QUESTIONS AND ANSWERS (VERIFIED AND UPDATED)

PSYCHOPHARMACOLOGY: MOOD
STABILIZERS, ANTIDEPRESSANTS, AND
OPIOID REVERSAL AGENTS. EXAM
QUESTIONS AND ANSWERS (VERIFIED
AND UPDATED)




Lithium Carbonate - ANS Mood stabilizer; MOA: alters sodium transport & stabilizes
serotonin/norepinephrine; Side effects: tremor, thirst/polyuria, GI upset, weight gain,
hypothyroidism, toxicity; Onset: 1-3 weeks.


Valproic Acid (Depakote) - ANS Mood stabilizer/anticonvulsant; MOA: increases GABA; Side
effects: hepatotoxicity, pancreatitis, thrombocytopenia, weight gain; Onset: days-weeks.


Sertraline (Zoloft) - ANS SSRI; MOA: blocks serotonin reuptake; Side effects: GI upset,
insomnia, sexual dysfunction, serotonin syndrome; Onset: 2-6 weeks.


Paroxetine (Paxil) - ANS SSRI; MOA: blocks serotonin reuptake; Side effects: sexual
dysfunction, weight gain, withdrawal symptoms, serotonin syndrome; Onset: 2-6 weeks.


Trazodone (Desyrel) - ANS Atypical antidepressant (SARI); MOA: serotonin reuptake inhibitor
+ 5HT2 antagonist, H1 and α1 blockade; Side effects: sedation, orthostatic hypotension,
priapism; Onset: sedation immediate, mood 1-2 weeks.




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