lOMoAR cPSD| 65448581
NURS 615 Exam 4 Review Questions | Actual study Questions
and verified Answers with Rationales complete Solutions | A+
Graded | 2026 Updates | 100% correct
Question 1
A patient in the emergency room (ER) has been prescribed ondansetron for nausea. The APN understands
that this medication works by which mechanism?
Question Options
• 1 ] Blocking dopamine receptors in the chemoreceptor trigger zone- phenathiazine 2 ]
Blocking histamine1 receptors in the gastrointestinal (GI) tract- antihistamines
3 ] Blocking serotonin on vagal nerve terminals
• 4 ] Stimulating gastric emptying and peristalsis- prokinetic agent – metoclopramide
Question 2
Which classification of respiratory medications results in bronchodilation effects and sputum volume
reduction in patients with chronic obstructive pulmonary disease (COPD)?
Question Options
• 1 ] Beta2 agonists- relax smooth muscle and bron dilation 2]
Methylxanthines-
3 ] Muscarinic agents
• 4 ] Phosphodiesterase-4 (PDE-4) inhibitors
Rationales
Option:
Beta2 agonists relax the bronchial smooth muscle cells causing bronchodilation but not sputum volume
reduction.
Option:
Methylxanthines has bronchodilation properties with phosphodiesterase-3 (PDE-3) and phosphodiesterase-4
(PDE-4) inhibition but not sputum volume reduction.
Option:
Muscarinic agents reduce the volume of sputum without changing the viscosity, in addition to their
bronchodilation effects.
Option:
, lOMoAR cPSD| 65448581
PDE-4s inhibit activation of the PDE-4 receptors located in the smooth muscles of the airways, resulting in
bronchial relaxation and a decrease in the activation of the immune response but not sputum volume
reduction. [Page reference: 962]
Question 3
Which condition is a clinical indication for antihistamines?
Question Options
• 1 ] Nervousness 2 ] Headache
3 ] Urticaria
• 4 ] Constipation
Correct Option/Answers: 3
Rationales
Option:
Nervousness is a possible adverse drug reaction to first-generation antihistamines, not a clinical indication for
their use.
Option:
Headache is a possible adverse drug reaction to first-generation antihistamines, not a clinical indication for
their use.
Option:
In urticaria, histamine is the primary mediator; therefore, the antihistamines are the drugs of choice and quite
effective.
Option:
Constipation is not a clinical indication for the use of antihistamines. [Page reference: 379]
Question 4
Pernicious anemia can develop in patients having long-term treatment with which class of drugs?
Question Options
• 1 ] Histamine2 receptor antagonists (H2RAs)
2 ] Proton pump inhibitors (PPIs)
• 3 ] Antacids
• 4 ] Prokinetic agents Correct Option/Answers:
Rationales
Option:
H2RAs suppress acid production but not 100%, so intrinsic factor is not affected.
Option:
Total suppression of gastric acid long-term can lead to a lack of intrinsic factor, which is also secreted by the
parietal cells. Intrinsic factor is needed to facilitate absorption of vitamin B12.
Option:
Antacids act as buffers and raise the gastric pH for short-term relief. They have no effect on acid secretion.
Option:
NURS 615 Exam 4 Review Questions | Actual study Questions
and verified Answers with Rationales complete Solutions | A+
Graded | 2026 Updates | 100% correct
Question 1
A patient in the emergency room (ER) has been prescribed ondansetron for nausea. The APN understands
that this medication works by which mechanism?
Question Options
• 1 ] Blocking dopamine receptors in the chemoreceptor trigger zone- phenathiazine 2 ]
Blocking histamine1 receptors in the gastrointestinal (GI) tract- antihistamines
3 ] Blocking serotonin on vagal nerve terminals
• 4 ] Stimulating gastric emptying and peristalsis- prokinetic agent – metoclopramide
Question 2
Which classification of respiratory medications results in bronchodilation effects and sputum volume
reduction in patients with chronic obstructive pulmonary disease (COPD)?
Question Options
• 1 ] Beta2 agonists- relax smooth muscle and bron dilation 2]
Methylxanthines-
3 ] Muscarinic agents
• 4 ] Phosphodiesterase-4 (PDE-4) inhibitors
Rationales
Option:
Beta2 agonists relax the bronchial smooth muscle cells causing bronchodilation but not sputum volume
reduction.
Option:
Methylxanthines has bronchodilation properties with phosphodiesterase-3 (PDE-3) and phosphodiesterase-4
(PDE-4) inhibition but not sputum volume reduction.
Option:
Muscarinic agents reduce the volume of sputum without changing the viscosity, in addition to their
bronchodilation effects.
Option:
, lOMoAR cPSD| 65448581
PDE-4s inhibit activation of the PDE-4 receptors located in the smooth muscles of the airways, resulting in
bronchial relaxation and a decrease in the activation of the immune response but not sputum volume
reduction. [Page reference: 962]
Question 3
Which condition is a clinical indication for antihistamines?
Question Options
• 1 ] Nervousness 2 ] Headache
3 ] Urticaria
• 4 ] Constipation
Correct Option/Answers: 3
Rationales
Option:
Nervousness is a possible adverse drug reaction to first-generation antihistamines, not a clinical indication for
their use.
Option:
Headache is a possible adverse drug reaction to first-generation antihistamines, not a clinical indication for
their use.
Option:
In urticaria, histamine is the primary mediator; therefore, the antihistamines are the drugs of choice and quite
effective.
Option:
Constipation is not a clinical indication for the use of antihistamines. [Page reference: 379]
Question 4
Pernicious anemia can develop in patients having long-term treatment with which class of drugs?
Question Options
• 1 ] Histamine2 receptor antagonists (H2RAs)
2 ] Proton pump inhibitors (PPIs)
• 3 ] Antacids
• 4 ] Prokinetic agents Correct Option/Answers:
Rationales
Option:
H2RAs suppress acid production but not 100%, so intrinsic factor is not affected.
Option:
Total suppression of gastric acid long-term can lead to a lack of intrinsic factor, which is also secreted by the
parietal cells. Intrinsic factor is needed to facilitate absorption of vitamin B12.
Option:
Antacids act as buffers and raise the gastric pH for short-term relief. They have no effect on acid secretion.
Option:
