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📋 DOCUMENT OVERVIEW 60 Qs
This document, "NSG 3850 - Exam 4," provides a comprehensive review of liver and endocrine system
concepts. The 60 questions cover topics such as the symptoms of chronic hepatitis C, the etiology of
cholelithiasis, risk factors for non-alcoholic steatohepatitis, and diagnostic tests for cholelithiasis. Each
question includes a correct answer with detailed explanations, allowing students to study, review, and
deepen their understanding of the material for exam preparation.
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EXAM QUESTIONS
QUESTION 1
S/S of chronic hep C?
CORRECT ANSWER
- encephalopathy
- changes in LOC
RATIONALE: Chronic hepatitis C infection can lead to liver cirrhosis and liver failure, which in turn causes
encephalopathy due to the buildup of toxins in the brain. This condition, characterized by changes in level of
consciousness (LOC), is a direct consequence of the liver's inability to filter these toxins effectively.
QUESTION 2
What is the etiology (cause) of cholelithiasis?
CORRECT ANSWER
Oversaturation of bile stones OR cholesterol stones
RATIONALE: Cholelithiasis, or the formation of gallstones, is primarily caused by the oversaturation of bile with either
bilirubin, resulting in pigment stones, or cholesterol, leading to cholesterol stones. This oversaturation occurs when there
is an imbalance in the normal balance of bile components, allowing crystals to form and aggregate into stones.
QUESTION 3
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, What are risk factors for non-alcoholic steatohepatitis/fatty liver?
CORRECT ANSWER
- DM
- obesity (BMI >30)
- high cholesterol
RATIONALE: Non-alcoholic steatohepatitis (NASH), also known as fatty liver, is a condition characterized by inflammation
of the liver due to excessive fat accumulation. The given risk factors, including diabetes mellitus (DM), obesity (BMI
>30), and high cholesterol, are all associated with metabolic syndrome, a cluster of conditions that increase the risk of
developing insulin resistance, inflammation, and fatty liver disease.
QUESTION 4
What are the diagnostic test(s) for cholelithiasis/cholecystitis?
CORRECT ANSWER
Ultrasound is first
*can do CT, MRI
RATIONALE: Ultrasound is first because it is a non-invasive, painless, and widely available imaging modality that can
effectively visualize the gallbladder and its contents, making it an ideal initial diagnostic test for cholelithiasis and
cholecystitis. The statement "can do CT, MRI" is incorrect, as these modalities are not typically used as the first line of
diagnosis for gallbladder diseases due to their higher cost, radiation exposure, and limited added value in comparison to
ultrasound.
QUESTION 5
How do we confirm cirrhosis?
CORRECT ANSWER
Liver biopsy
RATIONALE: A liver biopsy is the definitive method to confirm cirrhosis because it allows for a direct examination of liver
tissue, enabling pathologists to assess the extent of liver cell death, fibrosis, and architectural distortion characteristic of
cirrhosis. This invasive but highly accurate diagnostic approach is considered the gold standard for confirming cirrhosis
due to its ability to provide a precise diagnosis and guide further management.
QUESTION 6
What is the incubation period for hep A?
CORRECT ANSWER
2-7 weeks
RATIONALE: The incubation period for hepatitis A is typically 2-7 weeks because this range allows for the time it takes
for the virus to replicate and cause symptoms after exposure, which is a key aspect of the disease's progression. This
timeframe also takes into account the variability in individual immune responses and the potential for different strains of
the virus to have slightly different incubation periods.
QUESTION 7
What is the incubation period for hep B?
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, CORRECT ANSWER
2-6 months
RATIONALE: The incubation period for hepatitis B is a duration of time between exposure to the virus and the onset of
symptoms, which typically ranges from 2-6 months due to the virus's complex replication and integration process within
the host's liver cells. This prolonged period allows the virus to establish a chronic infection in some individuals, increasing
the risk of liver disease and other complications.
QUESTION 8
What is the incubation period for hep C?
CORRECT ANSWER
2-26 weeks
RATIONALE: The incubation period for hep C is typically "2-26 weeks" because it refers to the time interval between
exposure to the hepatitis C virus (HCV) and the onset of symptoms, which can vary greatly among individuals due to
factors like viral load and immune response. This wide range is a result of the fact that some people may not experience
symptoms at all, and the virus can remain dormant for years before causing liver damage.
QUESTION 9
What is the incubation period for hep D?
CORRECT ANSWER
Already have hep B so doesn't really matter
RATIONALE: The statement is correct because the incubation period for hepatitis D (hep D) is actually dependent on the
presence of hepatitis B (hep B) infection, as it can only replicate in the presence of the hepatitis B virus. Therefore, since
the person already has hepatitis B, the incubation period for hepatitis D is not applicable in the same way it would be for
someone without a hepatitis B infection.
QUESTION 10
What is the incubation period for hep E?
CORRECT ANSWER
2-9 weeks
RATIONALE: The incubation period for hepatitis E is generally considered to be between 2-9 weeks because it is the
timeframe during which the virus is replicating and causing liver damage without showing any noticeable symptoms. This
period can vary depending on several factors, including the individual's immune system, the viral load, and the presence
of any underlying health conditions.
QUESTION 11
How do we differentiate b/w the various types of hepatitis?
CORRECT ANSWER
Serologic testing
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