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CERTIFIED NEPHROLOGY NURSE EXAM QUESTIONS AND CORRECT ANSWERS

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This practice question set is designed for candidates preparing for the Certified Nephrology Nurse examination. It covers key nephrology nursing concepts including hemodialysis care, peritoneal dialysis, vascular access management, fluid and electrolyte balance, kidney disease progression, infection control, patient assessment, medication administration, and dialysis safety protocols. The content is structured to strengthen clinical knowledge, improve critical thinking, and support success in nephrology nursing certification exams.

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CERTIFIED NEPHROLOGY NURSE
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CERTIFIED NEPHROLOGY NURSE

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CERTIFIED NEPHROLOGY NURSE (CNN)
EXAMINATION QUESTIONS AND CORRECT
ANSWERS (VERIFIED ANSWERS) Q&A 2026
|INSTANT DOWLOAD PDF

1. Which organ is primarily responsible for maintaining fluid
and electrolyte balance in the body?
A. Liver
B. Heart
C. Kidneys
D. Lungs
Rationale: The kidneys regulate sodium, potassium, water, and
acid-base balance.
Correct Answer: C. Kidneys


2. The functional unit of the kidney is the:
A. Neuron
B. Nephron
C. Alveolus
D. Glomerulus
Rationale: The nephron is the microscopic structural and
functional unit of the kidney.
Correct Answer: B. Nephron

,3. Glomerular filtration primarily occurs in the:
A. Loop of Henle
B. Proximal tubule
C. Glomerulus
D. Collecting duct
Rationale: Filtration of blood plasma takes place in the
glomerulus.
Correct Answer: C. Glomerulus


4. The normal range for glomerular filtration rate (GFR) in
healthy adults is:
A. 10–30 mL/min
B. 30–60 mL/min
C. 90–120 mL/min
D. 150–200 mL/min
Rationale: Normal GFR is approximately 90–120 mL/min.
Correct Answer: C. 90–120 mL/min


5. The primary hormone that stimulates red blood cell
production is:
A. Insulin
B. Erythropoietin

,C. Aldosterone
D. Cortisol
Rationale: Erythropoietin is produced by the kidneys and
stimulates RBC production.
Correct Answer: B. Erythropoietin


6. A common cause of chronic kidney disease (CKD) is:
A. Asthma
B. Diabetes mellitus
C. Appendicitis
D. Otitis media
Rationale: Diabetes is the leading cause of CKD worldwide.
Correct Answer: B. Diabetes mellitus


7. The most accurate indicator of renal function is:
A. Blood urea nitrogen (BUN)
B. Serum creatinine
C. Urine color
D. Blood glucose
Rationale: Serum creatinine best reflects kidney filtration
ability.
Correct Answer: B. Serum creatinine

, 8. Hemodialysis works primarily by:
A. Active transport
B. Osmosis only
C. Diffusion across a semipermeable membrane
D. Filtration by liver
Rationale: Waste removal occurs via diffusion in dialysis.
Correct Answer: C. Diffusion across a semipermeable
membrane


9. The dialysate is best defined as:
A. Patient blood
B. Sterile saline only
C. A solution used to remove waste during dialysis
D. Anticoagulant fluid
Rationale: Dialysate helps remove toxins and balance
electrolytes.
Correct Answer: C. A solution used to remove waste during
dialysis


10. The most common vascular access for long-term
hemodialysis is:
A. Central venous catheter
B. Arteriovenous fistula

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CERTIFIED NEPHROLOGY NURSE
Vak
CERTIFIED NEPHROLOGY NURSE

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