IAL book topic linked to each paragraph of the Pearson Edexcel International
Advanced Level Scientific Article of Unit 5, June 2026
In unit 5, the last question (question 8) is based on a pre-released scientific article a total of 30
marks.
In this document, you will find a table with a one-sentence summary of what each paragraph covers
mapped to specific IAL Biology A Level chapter(s).
(The article is provided by Pearson Edexcel Examination – June 2026)
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, WBI15/01– Paragraph Topics and A Level Chapter Mapping Biology A Level Tutor
The table is a landscape Word document covering all 36 paragraphs. Each row contains three columns:
the paragraph number, a one-sentence summary of what it covers, and the specific IAL Biology A Level
chapter(s) it maps to.
The three article sections are colour-coded:
— green for "Beyond Tired",
— coral for "Problems with energy supply", and
— blue for "New treatments" — making it easy to navigate at a glance.
The most frequently appearing topics across the article are Topic 7.1 (Cellular respiration), Topic 8.2 and
8.3 (The nervous system and Brains and behaviour), Topic 6.2 and 6.3 (Microorganisms and disease /
People versus pathogens), and Topic 7.3 (The heart, energy and exercise) — which reflects how deeply
the article integrates neuroscience, immunology, and bioenergetics.
Paragraph Topics and A Level Chapter Mapping
Scientific Article mapped to: Pearson Edexcel Salters-Nuffield International A Level Biology
Paragraph What the paragraph is about (one sentence) Relevant A Level chapter(s)
Section 1: Beyond Tired: Why Fatigue Sets In and How to Tackle It
Paragraphs 1 to 11
Topic 7.4: Health, exercise and sport —
Fatigue has become widespread recently, affecting
1 The risks of too little/too much
many people with bone-deep tiredness.
exercise
Fatigue is the most universal symptom of the COVID- Topic 6.2: Microorganisms and disease
2 19 pandemic, appearing as long covid, burnout and — Invading the body; Non-specific
Zoom fatigue. responses to infection
The pandemic has pushed fatigue to the forefront of
Topic 7.4: Health, exercise and sport;
3 science, having previously been dismissed as lacking a
Topic 6.3: People versus pathogens
clear biological origin.
Research now shows fatigue results from a body- Topic 7.1: Cellular respiration —
4 brain dialogue about cellular energy, affecting ~1% of Introducing cellular respiration; Topic
the global population chronically. 8.3: Brains and behaviour
Topic 7.1: Cellular respiration; Topic
Many different triggers cause fatigue (flu, exercise,
6.2: Microorganisms and disease;
5 long covid) but all manifest similarly in the brain,
Topic 8.2: How the nervous system
differing only in what drains energy.
works
VanElzakker uses a forest fire analogy to illustrate
Topic 8.2: How the nervous system
6 that different causes of fatigue all lead to the same
works — Coordination at work
biological outcome.
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