1|Page
# NURS 6501N WEEK 2 QUIZ – ADVANCED
PATHOPHYSIOLOGY
## WALDEN UNIVERSITY (A+ GRADE) 2026-2027
EDITION
### 100 MULTIPLE CHOICE QUESTIONS WITH
ANSWERS & RATIONALES
## Table of Contents
| Section | Topic Area | Question Numbers |
|---------|------------|------------------|
| **Part 1** | Immunity & Hypersensitivity Reactions | 1-25 |
| **Part 2** | Infectious Diseases & Pathogens | 26-45 |
| **Part 3** | Inflammation & Inflammatory Response | 46-60 |
| **Part 4** | Autoimmune & Musculoskeletal Disorders | 61-75 |
| **Part 5** | Stress, Cancer & Genetic Disorders | 76-90 |
| **Part 6** | Mixed High-Yield Review | 91-100 |
---
,2|Page
## PART 1: IMMUNITY & HYPERSENSITIVITY REACTIONS
**Question 1:**
A patient presents with poison ivy on the extremities, face, and buttocks.
This condition is an example of which type of hypersensitivity reaction?
A. Type I (Anaphylactic)
B. Type II (Cytotoxic)
C. Type III (Immune complex-mediated)
D. Type IV (Delayed hypersensitivity)
**Answer: D**
*Rationale:* Poison ivy dermatitis is a classic example of Type IV
delayed hypersensitivity mediated by T cells (not antibodies). The
reaction occurs 24-72 hours after exposure as sensitized T lymphocytes
release cytokines that recruit macrophages, causing inflammation.
**Question 2:**
A nurse recalls an example of an immune-complex-mediated disease is:
A. Anaphylaxis
,3|Page
B. Hemolytic anemia
C. Serum sickness
D. Contact dermatitis
**Answer: C**
*Rationale:* Serum sickness is a Type III hypersensitivity reaction
where antigen-antibody complexes deposit in tissues (vessels, kidneys,
joints), activating complement and causing inflammation. Anaphylaxis is
Type I, hemolytic anemia is Type II, and contact dermatitis is Type IV.
**Question 3:**
When a patient asks the nurse what hypersensitivity is, how should the
nurse respond? Hypersensitivity is best defined as:
A. A deficiency of the immune system
B. A normal response to any antigen
C. An excessive or inappropriate response of the immune system to a
sensitizing antigen
D. A response that only occurs with bacterial infections
**Answer: C**
, 4|Page
*Rationale:* Hypersensitivity is an exaggerated or inappropriate
immune response to an antigen that causes tissue damage. It can be
mediated by antibodies or T cells and is classified into four types.
**Question 4:**
A 30-year-old male is having difficulty breathing and has been spitting
blood. He reports that he began experiencing this reaction after cleaning
his pigeons' cages. Testing reveals he is suffering from allergic alveolitis.
Which of the following is he experiencing?
A. Type I hypersensitivity
B. Type II hypersensitivity
C. Type III hypersensitivity (Arthus reaction)
D. Type IV hypersensitivity
**Answer: C**
*Rationale:* Allergic alveolitis (hypersensitivity pneumonitis) from
pigeon exposure is a Type III hypersensitivity reaction. It involves the
formation of precipitating antibodies (IgG) that form immune complexes
in the alveoli, leading to complement activation and inflammation. This
is known as an Arthus reaction (localized Type III).
# NURS 6501N WEEK 2 QUIZ – ADVANCED
PATHOPHYSIOLOGY
## WALDEN UNIVERSITY (A+ GRADE) 2026-2027
EDITION
### 100 MULTIPLE CHOICE QUESTIONS WITH
ANSWERS & RATIONALES
## Table of Contents
| Section | Topic Area | Question Numbers |
|---------|------------|------------------|
| **Part 1** | Immunity & Hypersensitivity Reactions | 1-25 |
| **Part 2** | Infectious Diseases & Pathogens | 26-45 |
| **Part 3** | Inflammation & Inflammatory Response | 46-60 |
| **Part 4** | Autoimmune & Musculoskeletal Disorders | 61-75 |
| **Part 5** | Stress, Cancer & Genetic Disorders | 76-90 |
| **Part 6** | Mixed High-Yield Review | 91-100 |
---
,2|Page
## PART 1: IMMUNITY & HYPERSENSITIVITY REACTIONS
**Question 1:**
A patient presents with poison ivy on the extremities, face, and buttocks.
This condition is an example of which type of hypersensitivity reaction?
A. Type I (Anaphylactic)
B. Type II (Cytotoxic)
C. Type III (Immune complex-mediated)
D. Type IV (Delayed hypersensitivity)
**Answer: D**
*Rationale:* Poison ivy dermatitis is a classic example of Type IV
delayed hypersensitivity mediated by T cells (not antibodies). The
reaction occurs 24-72 hours after exposure as sensitized T lymphocytes
release cytokines that recruit macrophages, causing inflammation.
**Question 2:**
A nurse recalls an example of an immune-complex-mediated disease is:
A. Anaphylaxis
,3|Page
B. Hemolytic anemia
C. Serum sickness
D. Contact dermatitis
**Answer: C**
*Rationale:* Serum sickness is a Type III hypersensitivity reaction
where antigen-antibody complexes deposit in tissues (vessels, kidneys,
joints), activating complement and causing inflammation. Anaphylaxis is
Type I, hemolytic anemia is Type II, and contact dermatitis is Type IV.
**Question 3:**
When a patient asks the nurse what hypersensitivity is, how should the
nurse respond? Hypersensitivity is best defined as:
A. A deficiency of the immune system
B. A normal response to any antigen
C. An excessive or inappropriate response of the immune system to a
sensitizing antigen
D. A response that only occurs with bacterial infections
**Answer: C**
, 4|Page
*Rationale:* Hypersensitivity is an exaggerated or inappropriate
immune response to an antigen that causes tissue damage. It can be
mediated by antibodies or T cells and is classified into four types.
**Question 4:**
A 30-year-old male is having difficulty breathing and has been spitting
blood. He reports that he began experiencing this reaction after cleaning
his pigeons' cages. Testing reveals he is suffering from allergic alveolitis.
Which of the following is he experiencing?
A. Type I hypersensitivity
B. Type II hypersensitivity
C. Type III hypersensitivity (Arthus reaction)
D. Type IV hypersensitivity
**Answer: C**
*Rationale:* Allergic alveolitis (hypersensitivity pneumonitis) from
pigeon exposure is a Type III hypersensitivity reaction. It involves the
formation of precipitating antibodies (IgG) that form immune complexes
in the alveoli, leading to complement activation and inflammation. This
is known as an Arthus reaction (localized Type III).
