PACK KEY MICROBIAL PATHOGENESIS
IMMUNOLOGY AND LAB METHODS WITH
SAMPLE QUESTIONS
◉ what is the target of macrolides? Answer: protein synthesis
◉ what is the target of mupirocin? Answer: protein synthesis
◉ what is the target of quinupristin? Answer: protein synthesis
◉ what is the target of rifamycins? Answer: transcription
◉ what is the target of sulfa drugs? Answer: folate
synthesis/metabolism
◉ what is the target of oxasolidinones? Answer: protein synthesis
◉ what is the target of tetracyclines? Answer: protein synthesis
, ◉ what is the target of trimethoprim? Answer: folate
synthesis/metabolism
◉ which two antibiotics interfere with the A site on 30S subunit?
Answer: tetracyclines
aminoglycosides
◉ what antibiotic interferes with th Ile-tRNA synthetase? Answer:
mypirocin
◉ which two antibiotics interfere with EF-Tu? Answer: kirromycin
LFF571
◉ Which antibiotics interfere with he exit tunnel in 50s subunit?
Answer: macrolides
lincomycin
quinupristin
◉ what antibiotic interferes with the P site on 30S subunit? Answer:
kasugamycin
◉ which antibiotics interfere with the PTC on 50S subunit? Answer:
dalfopristin