Page 1 of 5
RANDOM CLINICAL PEARLS CPJE EXAM |
FREQUENTLY TESTED QUESTIONS WITH
CORRECT ANSWERS | BRAND NEW!
Anakinra (Kineret) dosing freq - ✔✔✔ Correct Answer > Once daily SQ
IL-1 receptor antagonist, Biological DMARDs
For: RA
Etanercept (Enbrel) dosing freq - ✔✔✔ Correct Answer > Once or twice
weekly
Bio DMARD
Adalimumab (Humira) dosing freq - ✔✔✔ Correct Answer > once
weekly or every 2 weeks SQ
Golimumab (Simponi) dosing freq - ✔✔✔ Correct Answer > once
monthly SQ
, Page 2 of 5
Tocilizumab (Actemra) - ✔✔✔ Correct Answer > once weekly or every 2
weeks SQ
Hydroxychloroquine advantage vs caution - ✔✔✔ Correct Answer >
advantage: lack of hepatic or renal toxicity & lack of
myelosuppression
caution: may cause vision change or hearing change
Leflunomide (Arava) advantage vs caution - ✔✔✔ Correct Answer >
advantage: can be removed by cholesteyramine or activated
charcoal
caution: Preg cat X and hepatotoxic
Sulfasalazine affect on folate - ✔✔✔ Correct Answer > can affect folate
absorption (take folate 1mg daily)
MTX affect on folate - ✔✔✔ Correct Answer > can cause folate
deficiency (take folic acid 5-7mg weekly on day following MTX or
1mg QD to reduce SE e.g. N/V mouth ulcers)
What reduces toxicity of MTX - ✔✔✔ Correct Answer > Leucovorin
RANDOM CLINICAL PEARLS CPJE EXAM |
FREQUENTLY TESTED QUESTIONS WITH
CORRECT ANSWERS | BRAND NEW!
Anakinra (Kineret) dosing freq - ✔✔✔ Correct Answer > Once daily SQ
IL-1 receptor antagonist, Biological DMARDs
For: RA
Etanercept (Enbrel) dosing freq - ✔✔✔ Correct Answer > Once or twice
weekly
Bio DMARD
Adalimumab (Humira) dosing freq - ✔✔✔ Correct Answer > once
weekly or every 2 weeks SQ
Golimumab (Simponi) dosing freq - ✔✔✔ Correct Answer > once
monthly SQ
, Page 2 of 5
Tocilizumab (Actemra) - ✔✔✔ Correct Answer > once weekly or every 2
weeks SQ
Hydroxychloroquine advantage vs caution - ✔✔✔ Correct Answer >
advantage: lack of hepatic or renal toxicity & lack of
myelosuppression
caution: may cause vision change or hearing change
Leflunomide (Arava) advantage vs caution - ✔✔✔ Correct Answer >
advantage: can be removed by cholesteyramine or activated
charcoal
caution: Preg cat X and hepatotoxic
Sulfasalazine affect on folate - ✔✔✔ Correct Answer > can affect folate
absorption (take folate 1mg daily)
MTX affect on folate - ✔✔✔ Correct Answer > can cause folate
deficiency (take folic acid 5-7mg weekly on day following MTX or
1mg QD to reduce SE e.g. N/V mouth ulcers)
What reduces toxicity of MTX - ✔✔✔ Correct Answer > Leucovorin
