CONCEPTS FOR BIOLOGY AND HEALTH |COMPLETE
STUDY GUIDE WITH 100% ACCURATE QUESTIONS
&ANSWERS. EXCELLENCE GUARANTEED.
What are eicosanoids derived from? Answer: Essential fatty acids (EFAs)
What roles do eicosanoids play in the body? Answer: They are involved in
inflammation, blood clotting, and vascular function.
How does the balance between omega-3 and omega-6 eicosanoids affect health?
Answer: It influences pro-inflammatory versus anti-inflammatory responses.
What are essential fatty acids (EFAs) required for? Answer: Synthesis of lipid
biomediators and production of membrane phospholipids.
What are the two main types of essential fatty acids? Answer: Linoleic Acid (omega-6)
and Alpha-Linolenic Acid (omega-3).
Where does EFA metabolism primarily occur? Answer: In the smooth endoplasmic
reticulum.
What is the first step in the metabolism of omega-6 and omega-3 fatty acids? Answer:
Delta-6 desaturase.
What are the three main classes of eicosanoids? Answer: Prostaglandins (PG),
Thromboxanes (TX), and Leukotrienes (LT).
What do COX enzymes metabolize? Answer: Arachidonic Acid (AA) or
Eicosapentaenoic Acid (EPA) into prostaglandins and thromboxanes.
What is the role of leukotrienes in the body? Answer: They are inflammatory mediators,
particularly in allergic reactions.
What is the function of COX-1? Answer: It is constitutively expressed and produces
prostaglandins for stomach lining protection.
What is the primary role of thromboxanes? Answer: To induce platelet aggregation and
promote clot formation.
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