2026 COMPLETE QUESTIONS AND
ANSWERS GRADED A+
◉ older adult drug distribution change. Answer: decreased albumin
and binding = more free drugs = high chance toxicity
◉ older adult drug metabolism changes. Answer: rate slowed
decreased hepatic BF / liver mass = higher response to oral drugs
◉ older adult drug excretion changes. Answer: decreased renal BF =
high drug accumulation, high adverse effects
◉ older adult pharmacodynamic changes. Answer: receptor
alteration = more intense effects
beta blockers less effective
◉ Beers List. Answer: potentially inappropriate medications in the
elderly
◉ end of life care. Answer: disease prevention becomes comfort
inappropriate drugs may become appropriate and vice versa
, ◉ pharmacokinetics. Answer: the study of drug movement
throughout the body
◉ absorption. Answer: drug movement from the site of injection into
the blood
◉ increased lipid solubility leads to ____ absorption. Answer:
increased
◉ IV absorption. Answer: immediate
◉ IM / subcutaneous absorption. Answer: rapid if H2O soluble
poor if not
◉ oral absorption. Answer: slow, variable
◉ enteral. Answer: within GI tract - oral
◉ parenteral. Answer: outside GI tract - IV, IM, subcutaneous
◉ distribution. Answer: drug travels from blood into tissue and cells