NCLEX Practice Test Nursing 1 Questions and Answers, 2026/2027 – Comprehensive Exam Preparation Study Guide

NCLEX Practice Test questions- Nursing 1 questions and
answers 2026\2027 A+ Grade


A client has a continuously running peripheral infusion. The physician orders an antibiotic as a piggyback
infusion four times per day. In order to administer the antibiotic, the nurse should do which of the
following? Select all that apply.

1. Avoid compatibility issues by starting an additional IV access.

2. Start a new IV access to eliminate the problem of too much volume for one site.

3. Flush the IV line before and after infusion of an incompatible drug.

4. Check to see if the antibiotic is compatible with the continuous infusion.

5. Change the flow rate to facilitate the administration of the antibiotic.
- correct answer Answer: 3,4, 5



The family of a home infusion client calls the home health nurse one night to report that the electronic
infusion pump is alarming. What should the nurse anticipate as the cause of the infusion pump
alarming? Select all that apply.

1. The client's pulse and blood pressure are falling.

2. The client is experiencing a reaction to the medication.

3. The prescribed infusion is complete.

4. There is an incompatibility with the medications.

5. An occlusion has interrupted the infusion.
- correct answer Answer 3, 5



The home health nurse is monitoring a client who performs self- care of a central line. The nurse
observes the client doing all of the following activities. Which activity indicates the need for further
education?

1. Flushing the central line with a 3 mL syringe

2. Cleaning the needleless injection cap with alcohol before accessing

,3. Using sterile gloves to change the central line dressing 4. Wearing a mask while changing the central
line dressing
- correct answer Answer 1



The client has a tunneled Groshong catheter for intermittent medication administration. After
administering the medication, the nurse prepares to do which of the following?

1. Clamp the catheter after medication administration.

2. Flush the catheter with heparin at scheduled times.

3. Flush the catheter with saline after medication administration.

4. Initiate a Valsalva maneuver when disconnecting medication tubing.
- correct answer Answer 3



The client has a percutaneous jugular central venous line that is capped and used for intermittent
infusions. After administering the medication, the best method to maintain patency is to do which of the
following?

1. Flush the line first with 3- 5 mL of normal saline, then with 1- 3 mL of heparinized normal saline.

2. Flush the line with 3- 5 mL of normal saline.

3. Flush the line with 3- 5 mL of heparinized normal saline.

4. Flush the line first with 3- 5 mL of heparin, then with 1- 3 mL of normal saline.
- correct answer Answer 1



The nurse is caring for a client with a Hickman central line. While changing the central line dressing, the
nurse notes that the injection cap ( e. g., heplock adapter) is of the slip lock variety instead of a luer lock
device. The nurse recognizes that this adapter puts the client at risk for which complication?

1. Sepsis

2. Occlusion

3. Phlebitis

4. Air embolism
- correct answer Answer 4



The client is to receive the intravenous medication vancomycin ( Vancocin). To prevent adverse
reactions from rapid infusion, by what method should the nurse plan to administer this drug?

1. Using gravity

,2. With a regulator

3. Electronic infusion pump

4. Elastomeric pump
- correct answer Answer 3



The physician is going to order a hypotonic intravenous solution for a client with cellular dehydration.
The nurse would expect which fluid to be administered?

1. 0.9% normal saline

2. 5% dextrose in normal saline

3. Lactated Ringer's solution

4. 0.45% sodium chloride
- correct answer Answer 4



The nurse is caring for several clients with central venous catheters. While changing the tubing on the
central lines, the nurse would not need to instruct the client to perform Valsalva maneuver when the
client has which catheter?

1. Groshong

2. Single- lumen

3. Percutaneous

4. Accessed subcutaneous venous port
- correct answer Answer 1



The client is receiving 5% dextrose in 0.45% sodium chloride. The physician has ordered the client
receive one unit of packed cells. Prior to hanging the blood, the nurse will prime the blood tubing with
which solution?

1. 5% dextrose

2. Lactated Ringer's

3. 0.9% sodium chloride

4. 5% dextrose in 0.45% sodium chloride
- correct answer Answer 3

, While assessing a client's intravenous ( IV) line, the nurse notes that the area is swollen, cool, pale, and
causes the client discomfort. What complication should the nurse document?

1. Infiltration

2. Phlebitis

3. Infection

4. Air embolism
- correct answer Answer 1



The client is receiving 5% dextrose and 0.45% sodium chloride intravenously and is complaining of pain
at the IV site. The nurse assesses the site and notes erythema and edema. What is the appropriate
action for the nurse to take? Select all that apply.

1. Slow the infusion to a keep- open rate.

2. Discontinue the IV and apply a warm compress to the IV site.

3. Apply antibiotic ointment to the IV site.

4. Gently pull back on the IV catheter to attempt repositioning.

5. Relocate the IV site and document the event.
- correct answer Answer 2,5



The nurse is preparing to start a peripheral intravenous ( IV) line in a client. The client's record indicates
a latex allergy. What action should be taken by the nurse?

1. Utilize a new tourniquet for this client.

2. Use a blood pressure cuff to distend the vein.

3. Avoid putting povidone iodine on the skin.

4. Initiate a latex- free alternative therapy.
- correct answer Answer 2



The nurse is inserting an intravenous ( IV) line into a cli-ent. After piercing the skin and entering the vein,
what manifestation should cause the nurse to refrain from advancing the catheter?

1. Blood backflow into the IV catheter

2. Mild resistance with advancement

3. No reports of client discomfort