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-Tumors in the APEX of the lung, occur both in squamous cell and
adenocarcinomatous cancers.
-Sisns to look for: Sharp pleuritic pain in the axilla, shoulder, subscapular
area of the affected side, with atrophy and weakness of the upper extremity
muscles and hand intrinsics.
-Other manifestations: Digital clubbing, skin changes, joint swelling,
decreased or absent breath sounds
Adenocarcinoma
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, -Most common form of lung cancer in the United States, tends to arise in
the periphery, usually in the upper lobes at different levels of the bronchial
tree.
-The tumor spreads in the airways and to the lymph nodes, and eventually
in the blood.
-Refers to a heterogeneous group of neoplasms that have in common the
formation of land-like structures.
-It is further subdivided into 4 categories: Acinar, papillary,
bronchioloalveolar, and solid carcinoma.
-occurs more often in smokers, but it's the most common form of lung
cancer in non-smokers
Lung Cancer Etiology
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-Environment (smoking, secondhand smoke, occupational exposure and air
pollution)
-Nutrition
-Genetic factors (Enzymes for carcinogen metabolism, enzymes that
detoxify, and the capacity to repair DNA damage)
-Age, family history, medical history, especially lung disease, also influence
occurrence, morbidity, and mortality.
Lung Cancer Lab and Diagnostics
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