PNB 2275 LAB PRACTICAL I EXAM COMPLETE 200 QUESTIONS AND
VERIFIED SOLUTIONS LATEST UPDATE THIS YEAR
Blood is a type of __ tissue that is able to regenerate itself on a regular basis -
ANSWER-connective
If you spin a blood sample in a centrifuge on top is __, which makes up about __%
of blood. - ANSWER-Plasma; 55%
It is mainly consisting of water and also proteins and other dissolved solutes, such
as urea, salts, and organic nutrients. - ANSWER-plasma
If you spin a blood sample in a centrifuge, the middle layer is a grey-white layer,
called a __. - ANSWER-buffy coat
This layer contains platelets and various WBCs (leukocytes) - ANSWER-buffy
coat
If you spin a blood sample in a centrifuge, the bottom layer consists of __ and is
about __% of the blood. - ANSWER-red blood cells (erythrocytes); 44%
Collectively, the __ & __ are called the "formed elements". - ANSWER-
erythrocytes & the buffy coat
help initiate immune responses and defend the body against pathogens -
ANSWER-WBCs
How much bigger or smaller are WBCs compared to RBCs? - ANSWER-They are
about 1.5-3x larger than RBCs.
1
,WBCs are/are not motile - ANSWER-ARE motile
WBCs are mostly found in the __ rather than the __ - ANSWER-body tissues
rather than the blood stream
What are the 5 different types of WBCs - ANSWER-Neutrophils, Lymphocytes,
Monocytes, Eosinophils, Basophils (Never Let Monkeys Eat Bananas)
How do you view all of the components of blood? - ANSWER-by preparing a
blood smear slide
What are the two major classes of leukocytes? - ANSWER-granulocytes &
agranulocytes
Which leukocytes are granulocytes? - ANSWER-the phils! -> neutrophils,
eosinophils, basophils
Which leukocytes are agranulocytes? - ANSWER-A Little Monkey ->
lymphocytes & monocytes
When viewed under the microscope, granulocytes have visible microscopic __ in
the cytoplasm. - ANSWER-granules
__ are the most abundant WBC type and their nuclei are __. - ANSWER-
Neutrophils; multi-lobed
2
,have red-pink granules in their cytoplasm and their nuclei are __. - ANSWER-
Eosinophils; bi-lobed nuclei with two lobes connected by a strand
These make up about 2-4% of leukocytes, second most common. - ANSWER-
Eosinophils
Eosinophilia (an increase in the number of eosinophils in the blood) is likely to
come from a patient with __. - ANSWER-an allergic reaction or a parasitic
infection
__ are the least numerous type of leukocyte. They also have __ nuclei & blue-
violet __ - ANSWER-Basophils; bi-lobed nuclei; granules
Agranulocytes do/do not have granules in their cytoplasm/ - ANSWER-
Technically they still have granules in their cytoplasm, but they are much smaller
so they are often over-looked.
__ have large, round nuclei - ANSWER-Lymphocytes
__ have kidney-shaped nuclei - ANSWER-Monocytes
This disease is inherited and is caused by a single point mutation in the gene for
the Hb beta chain. - ANSWER-Sickle cell anemia
Sickle cell anemia is inherited and is caused by a single __ mutation in the gene for
the Hb __ chain, causing the cells to adopt a sickle shape and not be able to carry
as much oxygen. - ANSWER-caused by a single POINT mutation in the gene for
the Hb BETA chain
3
, What is the point mutation that causes sickle cell anemia? - ANSWER-GAG ->
GUG, which is a valine amino acid, rather than a glutamic acid
a higher density of RBCs is characteristic of __ - ANSWER-polycythemia
The elevated proportion of RBCs in polycythemia is result of either __ or __ -
ANSWER-the result of either an increase in the number of RBCs or a decrease in
blood plasma volume
Polycythemia can be a dangerous condition when the blood becomes too __ and
can result in __ & __. - ANSWER-viscous; high blood pressure & clots
Primary polycythemia is a rare caused by __. - ANSWER-factors intrinsic to RBC
precursors found in bone marrow (Hormones like erythropoietin can increase
production of erythrocytes. Chronic hypoxia and steroid hormones such as
testosterone can also contribute to polycythemia.)
Blood doping is an example of transfusional __ - ANSWER-polycythemia
This is a widespread viral disease characterized by fever, sore throat, and fatigue. -
ANSWER-Infectious mononucleosis
Infectious mononucleosis is most commonly caused by the __ virus - ANSWER-
Epstein-Barr
Infectious mononucleosis is characterized by atypical __ - ANSWER-
LYMPHOCYTES -> • When the disease was first characterized, clinicians
misidentified those atypical lymphocytes as monocytes and thus gave the disease
the misleading name of mononucleosis.
4
VERIFIED SOLUTIONS LATEST UPDATE THIS YEAR
Blood is a type of __ tissue that is able to regenerate itself on a regular basis -
ANSWER-connective
If you spin a blood sample in a centrifuge on top is __, which makes up about __%
of blood. - ANSWER-Plasma; 55%
It is mainly consisting of water and also proteins and other dissolved solutes, such
as urea, salts, and organic nutrients. - ANSWER-plasma
If you spin a blood sample in a centrifuge, the middle layer is a grey-white layer,
called a __. - ANSWER-buffy coat
This layer contains platelets and various WBCs (leukocytes) - ANSWER-buffy
coat
If you spin a blood sample in a centrifuge, the bottom layer consists of __ and is
about __% of the blood. - ANSWER-red blood cells (erythrocytes); 44%
Collectively, the __ & __ are called the "formed elements". - ANSWER-
erythrocytes & the buffy coat
help initiate immune responses and defend the body against pathogens -
ANSWER-WBCs
How much bigger or smaller are WBCs compared to RBCs? - ANSWER-They are
about 1.5-3x larger than RBCs.
1
,WBCs are/are not motile - ANSWER-ARE motile
WBCs are mostly found in the __ rather than the __ - ANSWER-body tissues
rather than the blood stream
What are the 5 different types of WBCs - ANSWER-Neutrophils, Lymphocytes,
Monocytes, Eosinophils, Basophils (Never Let Monkeys Eat Bananas)
How do you view all of the components of blood? - ANSWER-by preparing a
blood smear slide
What are the two major classes of leukocytes? - ANSWER-granulocytes &
agranulocytes
Which leukocytes are granulocytes? - ANSWER-the phils! -> neutrophils,
eosinophils, basophils
Which leukocytes are agranulocytes? - ANSWER-A Little Monkey ->
lymphocytes & monocytes
When viewed under the microscope, granulocytes have visible microscopic __ in
the cytoplasm. - ANSWER-granules
__ are the most abundant WBC type and their nuclei are __. - ANSWER-
Neutrophils; multi-lobed
2
,have red-pink granules in their cytoplasm and their nuclei are __. - ANSWER-
Eosinophils; bi-lobed nuclei with two lobes connected by a strand
These make up about 2-4% of leukocytes, second most common. - ANSWER-
Eosinophils
Eosinophilia (an increase in the number of eosinophils in the blood) is likely to
come from a patient with __. - ANSWER-an allergic reaction or a parasitic
infection
__ are the least numerous type of leukocyte. They also have __ nuclei & blue-
violet __ - ANSWER-Basophils; bi-lobed nuclei; granules
Agranulocytes do/do not have granules in their cytoplasm/ - ANSWER-
Technically they still have granules in their cytoplasm, but they are much smaller
so they are often over-looked.
__ have large, round nuclei - ANSWER-Lymphocytes
__ have kidney-shaped nuclei - ANSWER-Monocytes
This disease is inherited and is caused by a single point mutation in the gene for
the Hb beta chain. - ANSWER-Sickle cell anemia
Sickle cell anemia is inherited and is caused by a single __ mutation in the gene for
the Hb __ chain, causing the cells to adopt a sickle shape and not be able to carry
as much oxygen. - ANSWER-caused by a single POINT mutation in the gene for
the Hb BETA chain
3
, What is the point mutation that causes sickle cell anemia? - ANSWER-GAG ->
GUG, which is a valine amino acid, rather than a glutamic acid
a higher density of RBCs is characteristic of __ - ANSWER-polycythemia
The elevated proportion of RBCs in polycythemia is result of either __ or __ -
ANSWER-the result of either an increase in the number of RBCs or a decrease in
blood plasma volume
Polycythemia can be a dangerous condition when the blood becomes too __ and
can result in __ & __. - ANSWER-viscous; high blood pressure & clots
Primary polycythemia is a rare caused by __. - ANSWER-factors intrinsic to RBC
precursors found in bone marrow (Hormones like erythropoietin can increase
production of erythrocytes. Chronic hypoxia and steroid hormones such as
testosterone can also contribute to polycythemia.)
Blood doping is an example of transfusional __ - ANSWER-polycythemia
This is a widespread viral disease characterized by fever, sore throat, and fatigue. -
ANSWER-Infectious mononucleosis
Infectious mononucleosis is most commonly caused by the __ virus - ANSWER-
Epstein-Barr
Infectious mononucleosis is characterized by atypical __ - ANSWER-
LYMPHOCYTES -> • When the disease was first characterized, clinicians
misidentified those atypical lymphocytes as monocytes and thus gave the disease
the misleading name of mononucleosis.
4
