TEST QUESTIONS AND SOLUTIONS GRADED A+
✔✔IgE mediated - ✔✔___ response may be mild (such as allergic rhinitis) or more
severe such as asthma (constriction of bronchioles)
✔✔anaphylaxis - ✔✔___ is a life threatening IgE mediated response
✔✔-inflammation of the eyes, nose, and respiratory tract (itching, sneezing, and
coughing)
-urticaria (hives)
-dermatitis - ✔✔what are 3 general manifestations of common allergic reactions
✔✔IgE - ✔✔anaphylactic response is a LIFE THREATENING ___ mediated response
✔✔-angioedema (swollen lips)
-bronchial constriction/ bronchial spasm
-laryngeal edema
-massive vasodilation
-pruitis (itching)
-uricaria (hives) - ✔✔what are the 6 manifestations of anaphylactic response?
✔✔type II- antibody mediated cytotoxic disorder - ✔✔___ is another type of
hypersensitivity disorder but it involved reactions against specific cells or tissues
✔✔IgG and IgM - ✔✔type II- antibody mediated cytotoxic disorder involves what 2
immunoglobins
✔✔blood transfusion reactions - ✔✔type II- antibody mediated cytotoxic disorder occurs
from ___ reactions
✔✔Type III immune complex hypersensitivity disorder - ✔✔___ is the formation of
immune complexes such as antigen-antibody
✔✔antigen-antibody - ✔✔type III immune complex disorder forms immune complexes
such as ___ that gather in specific places in the body and cause reactions
✔✔vessels
tissues - ✔✔type III- immune complex disorder may damage the inner lining of ___ or
be deposited in ___ such as the glomerulus, lungs, and joints
✔✔delayed
, 24-72 hours - ✔✔type IV cell mediated hypersensitivity disorder has a ___ response of
___
✔✔-autoimmune disorders
-contact dermatitis (posion ivy, cosmetics)
-organ transplant
-Tb skin test - ✔✔what are 4 examples of type IV cell mediated hypersensitivity disorder
✔✔IgE or T cell - ✔✔latex allergy is caused by ___ or ___ mediated response
✔✔latex gloves - ✔✔latex allergy is caused by ___
✔✔proteins - ✔✔latex allergy is triggered by ___ on latex gloves and may also have a
cross allergy to bananas, kiwis, and tomatoes
✔✔1. type I IgE mediated response (mast cells/ basophils)
2. type II antibody mediated cytotoxic disorders
3. type III immune complex disorder
4. type IV cell mediated hypersensitivity disorder
5. latex allergy - ✔✔what are the 5 hypersensitivity disorders?
✔✔1. donor- provides tissue
2. recipient/ host- receives tissue
3. human leukocyte antigens (HLA)
4. autologous graft- donor and recipient are same person
5. syngeneic- donor and recipient are identical twins. no risk of rejections
6. allogeneic (allograft)- donor and recipient have similar HLA types and may or may not
be related - ✔✔what are the 6 terms for transplant immunopathology
✔✔autologous graft - ✔✔___ is graft transplanted from one individual to the same
individual
✔✔syngenic - ✔✔___ is when donor and recipient are identical twins
✔✔allogenic/allograft - ✔✔___ is when the donor and recipient have similar HLA types
and may or may no be related
✔✔B and T cells - ✔✔___ are involved in transplant rejections
✔✔Hyperacute rejection (rare) - ✔✔___ is rejection almost immediately and may be
evident before surgery is even over
✔✔lack of blood flow and may turn white - ✔✔what are the signs and symptoms of
hyperacute rejection?