ALTERATIONS IN IMMUNITY AND INFLAMMATORY
COMPREHENSIVE EXAM UPDATED QUESTIONS AND
SOLUTIONS GRADED A+
✔✔IgD - ✔✔___ is usually elevated during chronic infection
✔✔inflammation, allergic, and parasitic response - ✔✔what 3 things does IgE respond
to?
✔✔surface of basophils and eosinophils; also found on mucosal surfaces - ✔✔where is
the immunoglobulin IgE found?
✔✔-mast cells
-histamine - ✔✔IgE activates ___ and triggers the release of ___ and other
inflammatory mediators
✔✔-thymus
-lymph nodes - ✔✔cell mediated immunity (T-lymphocytes) mature in the ___ and
reside in the ___
✔✔cellular immunity - ✔✔___ is also called cell-mediated immunity and is based on
action of specific kinds of T lymphocytes
✔✔60-70% - ✔✔cell mediated immunity (T-lymphocytes) is ___% of all lymphocytes
✔✔macrophages and dendritic cells - ✔✔antigens are "presented" to T cells by ___ and
___ cells
✔✔cancer cells and viruses - ✔✔cell mediated immunity (T-lymphocytes) mostly
destroy ___ and ___ (live inside host cells)
✔✔MASTER REGULATOR - ✔✔Helper T cells are also referred to as "___"
✔✔-stimulates B cells to produce antibodies
-activates T cell response stimulate
-designated as CD4 T cells - ✔✔what 3 things are helper T cells regulating?
✔✔regulator (suppressor) T cells - ✔✔___ suppress proliferation of immune cells to
prevent exaggerated immune response
✔✔cytokines - ✔✔___ are proteins that are produced during ALL types of immune
responses - they regulate host reaction and leukocyte behavior
, ✔✔host reaction and leukocyte behavior - ✔✔cytokines are proteins that are produced
during ALL types of immune responses - they regulate ___ reaction and ___ behavior
✔✔-innate
-acquired - ✔✔immunity branches into what two types of immunity?
✔✔-active (own antibodies)
-passive (ready made antibodies) - ✔✔active immunity branches into what two types
✔✔-natural exposure to infectious agent
-artificial immunization - ✔✔active acquired immunity can occur from what 2 ways
✔✔-natural maternal antibodies
-artificial antibodies from other sources - ✔✔passive acquired immunity can occur from
what 2 ways
✔✔-maternal IgG antibodies transferred to infant- cross the placenta
-maternal IgA antibodies may be transferred to infants in breast milk - ✔✔what are 2
ways the transfer of immunity from mother to infant can happen?
✔✔-decrease in ability to fight off infection
-more susceptible to infections, autoimmune disorders, and cancer
-thymus gland decreases in size and can affect T cells that mature - ✔✔what are 3
changes in the immune response of the elderly
✔✔hypersensitivity disorder - ✔✔___ is an EXAGGERATED immune response that
may result in injury to the host
✔✔Type 1 IgE-Mediated response (mast/ basophils) - ✔✔what is the 1st type of
hypersensitivity disorder
✔✔allergic reaction - ✔✔Type 1 IgE-Mediated Hypersensitivity Response (mast/
basophils) is caused by ___ reactions
✔✔Type 1 IgE-Mediated hypersensitivity response (mast/ basophils) - ✔✔what is the
most common type of hypersensitivity disorder?
✔✔allergies - ✔✔Type 1 IgE-Mediated response (mast/ basophils) is genetic propensity
to ___
✔✔basophils, mast cells, and release of histamines - ✔✔Type 1 IgE-Mediated
hypersensitivity response (mast/ basophils) involves what 3 things
COMPREHENSIVE EXAM UPDATED QUESTIONS AND
SOLUTIONS GRADED A+
✔✔IgD - ✔✔___ is usually elevated during chronic infection
✔✔inflammation, allergic, and parasitic response - ✔✔what 3 things does IgE respond
to?
✔✔surface of basophils and eosinophils; also found on mucosal surfaces - ✔✔where is
the immunoglobulin IgE found?
✔✔-mast cells
-histamine - ✔✔IgE activates ___ and triggers the release of ___ and other
inflammatory mediators
✔✔-thymus
-lymph nodes - ✔✔cell mediated immunity (T-lymphocytes) mature in the ___ and
reside in the ___
✔✔cellular immunity - ✔✔___ is also called cell-mediated immunity and is based on
action of specific kinds of T lymphocytes
✔✔60-70% - ✔✔cell mediated immunity (T-lymphocytes) is ___% of all lymphocytes
✔✔macrophages and dendritic cells - ✔✔antigens are "presented" to T cells by ___ and
___ cells
✔✔cancer cells and viruses - ✔✔cell mediated immunity (T-lymphocytes) mostly
destroy ___ and ___ (live inside host cells)
✔✔MASTER REGULATOR - ✔✔Helper T cells are also referred to as "___"
✔✔-stimulates B cells to produce antibodies
-activates T cell response stimulate
-designated as CD4 T cells - ✔✔what 3 things are helper T cells regulating?
✔✔regulator (suppressor) T cells - ✔✔___ suppress proliferation of immune cells to
prevent exaggerated immune response
✔✔cytokines - ✔✔___ are proteins that are produced during ALL types of immune
responses - they regulate host reaction and leukocyte behavior
, ✔✔host reaction and leukocyte behavior - ✔✔cytokines are proteins that are produced
during ALL types of immune responses - they regulate ___ reaction and ___ behavior
✔✔-innate
-acquired - ✔✔immunity branches into what two types of immunity?
✔✔-active (own antibodies)
-passive (ready made antibodies) - ✔✔active immunity branches into what two types
✔✔-natural exposure to infectious agent
-artificial immunization - ✔✔active acquired immunity can occur from what 2 ways
✔✔-natural maternal antibodies
-artificial antibodies from other sources - ✔✔passive acquired immunity can occur from
what 2 ways
✔✔-maternal IgG antibodies transferred to infant- cross the placenta
-maternal IgA antibodies may be transferred to infants in breast milk - ✔✔what are 2
ways the transfer of immunity from mother to infant can happen?
✔✔-decrease in ability to fight off infection
-more susceptible to infections, autoimmune disorders, and cancer
-thymus gland decreases in size and can affect T cells that mature - ✔✔what are 3
changes in the immune response of the elderly
✔✔hypersensitivity disorder - ✔✔___ is an EXAGGERATED immune response that
may result in injury to the host
✔✔Type 1 IgE-Mediated response (mast/ basophils) - ✔✔what is the 1st type of
hypersensitivity disorder
✔✔allergic reaction - ✔✔Type 1 IgE-Mediated Hypersensitivity Response (mast/
basophils) is caused by ___ reactions
✔✔Type 1 IgE-Mediated hypersensitivity response (mast/ basophils) - ✔✔what is the
most common type of hypersensitivity disorder?
✔✔allergies - ✔✔Type 1 IgE-Mediated response (mast/ basophils) is genetic propensity
to ___
✔✔basophils, mast cells, and release of histamines - ✔✔Type 1 IgE-Mediated
hypersensitivity response (mast/ basophils) involves what 3 things
