MISSOURI MPJE CORE EXAM TEST 2026 QUESTIONS AND
SOLUTIONS GRADED A+
✔✔How must you report loss or theft to BNDD? - ✔✔Immediately report via phone, fax,
or email. Must submit loss report within 7 days.
✔✔T/F An agent from a prescribers office calls to authorize an emergency fill of
hydromorphone for pain for a patient requiring potent pain meds ASAP. She states the
pain is so severe only hydromorphone will do. She only authorizes a 3 day amount and
will have the Rx to you within the next few days. This is legal. - ✔✔False. Emergency
fills can only be verbally authorized by prescriber, not an agent.
✔✔How many refills are allowable on CIII-IV Rx? - ✔✔5 refills
✔✔How many refills are allowable on CV Rx? - ✔✔As authorized by physician.
✔✔What is the quantity limit on CIII-V Rx? - ✔✔90 day supply
✔✔How long is a CIII-IV Rx valid? - ✔✔6 months
✔✔How long is a CV Rx valid? - ✔✔1 year
✔✔What does CMEA stand for? - ✔✔Combat Methamphetamine Epidemic Act
✔✔Which form is used for new pharmacy registration with DEA? - ✔✔DEA Form 224
✔✔Which form is used to renew pharmacy registration with DEA? - ✔✔DEA Form 224a
✔✔Which form can be used to renew pharmacy registration with DEA for a chain
pharmacy? - ✔✔DEA Form 224b
✔✔What is required when a pharmacy chooses to terminate its registration with the
DEA? - ✔✔Return DEA registration certificate and unused DEA 222 Forms.
✔✔Which form is used by manufacturers to register with the DEA? - ✔✔DEA Form 225
✔✔What color is Copy 1, Copy 2, and Copy 3 of DEA 222 form? - ✔✔Copy 1 is brown.
Copy 2 is green. Copy 3 is blue.
✔✔What happens to each copy of the DEA 222 Form? - ✔✔Purchaser keeps Copy 3
for their records. Purchaser sends Copy 1 and 2 to the supplier to request drug order be
filled. Supplier retains Copy 1 for their files. Copy 2 is forwarded to the DEA by the
supplier. When purchaser receives drug order he/she should record, on Copy 3, the # of
each item and date received.
,✔✔If a supplier cannot fill a particular drug on the Form 222 submitted by the
purchaser, how long does the supplier have to ship that item? - ✔✔60 days.
✔✔Which form is used when a registrant destroys CS inventory? - ✔✔DEA Form 41
✔✔When a reverse distributor is used for destruction, who is responsible for submitting
DEA Form 41 to the DEA? Pharmacy or reverse distributor? - ✔✔Reverse distributor is
responsible.
✔✔T/F In order for a person to work in a pharmacy after having been convicted of a
felony related to CS, a waiver must be approved by the DEA. - ✔✔True.
✔✔Theft occurs at your pharmacy. How long do you have to notify the DEA? - ✔✔Notify
DEA within one business day of discovery. Notification should be in writing.
✔✔Which form is required to report theft or loss of CS to the DEA? - ✔✔DEA Form 106
✔✔How does the DEA define "significant loss"? - ✔✔DEA does not define significant
loss. They say you should use professional judgement.
✔✔A tote containing CS goes missing in-transit from the distributor to the pharmacy.
This is recognized before the pharmacist signs for the delivery. Who is responsible for
reporting the loss/theft to the DEA? Supplier or pharmacy? - ✔✔The supplier is
responsible.
✔✔A tote containing CS drugs is missing one bottle of methylphenidate. The
pharmacist discovers the drug is missing while putting the drug order away. Who is
responsible for reporting the loss/theft to the DEA? Supplier or pharmacy? - ✔✔The
pharmacy is responsible.
✔✔Per the Controlled Substance Registrant Protection Act, when is a federal
investigation appropriate following a theft of CS? - ✔✔Federal investigation is warranted
if cost of stolen CS is greater than $500, interstate or foreign commerce is involved, or if
a person is killed or significantly injured as a result.
✔✔T/F Hydrocodone/APAP gets re-scheduled as CII. The pharmacist is required to do
a full CS inventory at the time of re-scheduling? - ✔✔False. The pharmacist is required
to take inventory of the particular drug that has been re-scheduled on the day this
happens.
, ✔✔T/F The DEA requires documentation of Power of Attorney be submitted to them no
later than 14 days after RPh is given this responsibility. - ✔✔False. DEA does not
require this. Power of Attorney information should be filed in the pharmacy.
✔✔What does CSOS stand for? - ✔✔Controlled Substance Ordering System
✔✔List the letters that may be the first letter of a DEA number. - ✔✔A, B, F, or M (for
mid-level practitioners)
✔✔What determines the second letter of a DEA number? - ✔✔First letter of prescribers
last name.
✔✔What does it mean if a DEA number starts with X? - ✔✔This indicates the prescriber
is authorized to treat patients with Suboxone. The DEA number starting with X must be
present on Rx for Suboxone.
✔✔How many numbers are in a DEA number? - ✔✔Seven numbers.
✔✔How do you determine a DEA number is valid? - ✔✔Should begin with A, B, F, or M.
The second letter should be first letter of last name (keep in mind may reflect maiden
name for females). Add digits 1, 3, 5. Add digits 2, 4, 6 and multiply by 2. Add sum of
first equation and sum of second. The last digit of this sum should match last digit of
DEA number.
✔✔T/F A patient requests to have Rx for alprazolam transferred to another pharmacy.
The pharmacist may delegate the task to a tech if he/she is busy with a customer. -
✔✔False. CS transfers must be done between two RPhs!
✔✔John Smith is a LTCF patient with an order for Oxycontin. The pharmacist received
the order from the physician and has been partial filling. How long is the CS order good
for in LTCF patients? - ✔✔60 days
✔✔T/F A pharmacy is going to mail a Rx for zolpidem to a patient. They are required to
stamp a 2" C on the envelope prior to mailing. - ✔✔False. CS may be mailed if the
mailer has a DEA registration and it is packaged in plain paper with no indication that it
contains CS.
✔✔What does SLCP stand for? - ✔✔Scheduled listed chemical products.
✔✔How much pseudoephedrine can a person purchase in one day? - ✔✔No more than
3.6 grams of SLCP-containing product.
✔✔How much pseudoephedrine can a person purchase in 30 days? - ✔✔No more than
9 grams of SLCP-containing product.
SOLUTIONS GRADED A+
✔✔How must you report loss or theft to BNDD? - ✔✔Immediately report via phone, fax,
or email. Must submit loss report within 7 days.
✔✔T/F An agent from a prescribers office calls to authorize an emergency fill of
hydromorphone for pain for a patient requiring potent pain meds ASAP. She states the
pain is so severe only hydromorphone will do. She only authorizes a 3 day amount and
will have the Rx to you within the next few days. This is legal. - ✔✔False. Emergency
fills can only be verbally authorized by prescriber, not an agent.
✔✔How many refills are allowable on CIII-IV Rx? - ✔✔5 refills
✔✔How many refills are allowable on CV Rx? - ✔✔As authorized by physician.
✔✔What is the quantity limit on CIII-V Rx? - ✔✔90 day supply
✔✔How long is a CIII-IV Rx valid? - ✔✔6 months
✔✔How long is a CV Rx valid? - ✔✔1 year
✔✔What does CMEA stand for? - ✔✔Combat Methamphetamine Epidemic Act
✔✔Which form is used for new pharmacy registration with DEA? - ✔✔DEA Form 224
✔✔Which form is used to renew pharmacy registration with DEA? - ✔✔DEA Form 224a
✔✔Which form can be used to renew pharmacy registration with DEA for a chain
pharmacy? - ✔✔DEA Form 224b
✔✔What is required when a pharmacy chooses to terminate its registration with the
DEA? - ✔✔Return DEA registration certificate and unused DEA 222 Forms.
✔✔Which form is used by manufacturers to register with the DEA? - ✔✔DEA Form 225
✔✔What color is Copy 1, Copy 2, and Copy 3 of DEA 222 form? - ✔✔Copy 1 is brown.
Copy 2 is green. Copy 3 is blue.
✔✔What happens to each copy of the DEA 222 Form? - ✔✔Purchaser keeps Copy 3
for their records. Purchaser sends Copy 1 and 2 to the supplier to request drug order be
filled. Supplier retains Copy 1 for their files. Copy 2 is forwarded to the DEA by the
supplier. When purchaser receives drug order he/she should record, on Copy 3, the # of
each item and date received.
,✔✔If a supplier cannot fill a particular drug on the Form 222 submitted by the
purchaser, how long does the supplier have to ship that item? - ✔✔60 days.
✔✔Which form is used when a registrant destroys CS inventory? - ✔✔DEA Form 41
✔✔When a reverse distributor is used for destruction, who is responsible for submitting
DEA Form 41 to the DEA? Pharmacy or reverse distributor? - ✔✔Reverse distributor is
responsible.
✔✔T/F In order for a person to work in a pharmacy after having been convicted of a
felony related to CS, a waiver must be approved by the DEA. - ✔✔True.
✔✔Theft occurs at your pharmacy. How long do you have to notify the DEA? - ✔✔Notify
DEA within one business day of discovery. Notification should be in writing.
✔✔Which form is required to report theft or loss of CS to the DEA? - ✔✔DEA Form 106
✔✔How does the DEA define "significant loss"? - ✔✔DEA does not define significant
loss. They say you should use professional judgement.
✔✔A tote containing CS goes missing in-transit from the distributor to the pharmacy.
This is recognized before the pharmacist signs for the delivery. Who is responsible for
reporting the loss/theft to the DEA? Supplier or pharmacy? - ✔✔The supplier is
responsible.
✔✔A tote containing CS drugs is missing one bottle of methylphenidate. The
pharmacist discovers the drug is missing while putting the drug order away. Who is
responsible for reporting the loss/theft to the DEA? Supplier or pharmacy? - ✔✔The
pharmacy is responsible.
✔✔Per the Controlled Substance Registrant Protection Act, when is a federal
investigation appropriate following a theft of CS? - ✔✔Federal investigation is warranted
if cost of stolen CS is greater than $500, interstate or foreign commerce is involved, or if
a person is killed or significantly injured as a result.
✔✔T/F Hydrocodone/APAP gets re-scheduled as CII. The pharmacist is required to do
a full CS inventory at the time of re-scheduling? - ✔✔False. The pharmacist is required
to take inventory of the particular drug that has been re-scheduled on the day this
happens.
, ✔✔T/F The DEA requires documentation of Power of Attorney be submitted to them no
later than 14 days after RPh is given this responsibility. - ✔✔False. DEA does not
require this. Power of Attorney information should be filed in the pharmacy.
✔✔What does CSOS stand for? - ✔✔Controlled Substance Ordering System
✔✔List the letters that may be the first letter of a DEA number. - ✔✔A, B, F, or M (for
mid-level practitioners)
✔✔What determines the second letter of a DEA number? - ✔✔First letter of prescribers
last name.
✔✔What does it mean if a DEA number starts with X? - ✔✔This indicates the prescriber
is authorized to treat patients with Suboxone. The DEA number starting with X must be
present on Rx for Suboxone.
✔✔How many numbers are in a DEA number? - ✔✔Seven numbers.
✔✔How do you determine a DEA number is valid? - ✔✔Should begin with A, B, F, or M.
The second letter should be first letter of last name (keep in mind may reflect maiden
name for females). Add digits 1, 3, 5. Add digits 2, 4, 6 and multiply by 2. Add sum of
first equation and sum of second. The last digit of this sum should match last digit of
DEA number.
✔✔T/F A patient requests to have Rx for alprazolam transferred to another pharmacy.
The pharmacist may delegate the task to a tech if he/she is busy with a customer. -
✔✔False. CS transfers must be done between two RPhs!
✔✔John Smith is a LTCF patient with an order for Oxycontin. The pharmacist received
the order from the physician and has been partial filling. How long is the CS order good
for in LTCF patients? - ✔✔60 days
✔✔T/F A pharmacy is going to mail a Rx for zolpidem to a patient. They are required to
stamp a 2" C on the envelope prior to mailing. - ✔✔False. CS may be mailed if the
mailer has a DEA registration and it is packaged in plain paper with no indication that it
contains CS.
✔✔What does SLCP stand for? - ✔✔Scheduled listed chemical products.
✔✔How much pseudoephedrine can a person purchase in one day? - ✔✔No more than
3.6 grams of SLCP-containing product.
✔✔How much pseudoephedrine can a person purchase in 30 days? - ✔✔No more than
9 grams of SLCP-containing product.
