UNDERSTANDING
PATHOPHYSIOLOGY 6TH EDITION
STUDY GUIDE 2026
COMPREHENSIVE QUESTIONS AND
SOLUTIONS
◉ What is an iatrogenic disease? Answer:
Error/treatment/procedure may cause the disease
◉ The manifestations of a disease are best defined as the:
A. Subjective feelings of discomfort during a chronic illness
B. Signs and symptoms of a disease
C. Factors that precipitate an acute episode of a chronic illness
D. Early indicators of the prodromal stage of infection Answer: B.
Signs and symptoms of a disease
◉ The best definition of the term prognosis is the:
A. Precipitating factors causing an acute episode
B. Number for missions to be expected during the course of a
chronic illness
C. Predicted outcome or likelihood of recovery from a specific
disease
D. Exacerbations occurring during chronic illness Answer: C.
Predicted outcome or likelihood of recovery from a specific disease
, ◉ Which of the following is considered a systemic sign of disease?
A. Swelling of the knee
B. Fever
C. Pain in the neck
D. Red rash on the face Answer: B. Fever
◉ Define systemic Answer: Systemic means affecting the entire
body, rather than a single organ or body part.
Ex: High blood pressure
◉ Etiology is defined as the study of the:
A. Causes of disease
B. Course of a disease
C. Expected complications of a disease
D. Manifestations of a disease Answer: A. Causes of disease
◉ A type of cellular adaptation in which there is a decrease in cell
size is referred to as:
A. Hypertrophy
B. Metaplasia
C. Anaplasia
D. Atrophy Answer: D. Atrophy
PATHOPHYSIOLOGY 6TH EDITION
STUDY GUIDE 2026
COMPREHENSIVE QUESTIONS AND
SOLUTIONS
◉ What is an iatrogenic disease? Answer:
Error/treatment/procedure may cause the disease
◉ The manifestations of a disease are best defined as the:
A. Subjective feelings of discomfort during a chronic illness
B. Signs and symptoms of a disease
C. Factors that precipitate an acute episode of a chronic illness
D. Early indicators of the prodromal stage of infection Answer: B.
Signs and symptoms of a disease
◉ The best definition of the term prognosis is the:
A. Precipitating factors causing an acute episode
B. Number for missions to be expected during the course of a
chronic illness
C. Predicted outcome or likelihood of recovery from a specific
disease
D. Exacerbations occurring during chronic illness Answer: C.
Predicted outcome or likelihood of recovery from a specific disease
, ◉ Which of the following is considered a systemic sign of disease?
A. Swelling of the knee
B. Fever
C. Pain in the neck
D. Red rash on the face Answer: B. Fever
◉ Define systemic Answer: Systemic means affecting the entire
body, rather than a single organ or body part.
Ex: High blood pressure
◉ Etiology is defined as the study of the:
A. Causes of disease
B. Course of a disease
C. Expected complications of a disease
D. Manifestations of a disease Answer: A. Causes of disease
◉ A type of cellular adaptation in which there is a decrease in cell
size is referred to as:
A. Hypertrophy
B. Metaplasia
C. Anaplasia
D. Atrophy Answer: D. Atrophy
