COMPREHENSIVE QUESTIONS ANSWERED MULTIPLE
CHOICES 2026 VERIFIED GRADED A+ ALREADY
COMPREHENSIVE STUDY GUIDE 2026 QUESTIONS
WITH VERIFIED ANSWERS GRADED A+
ATI Comfort, Rest, and Sleep Exam
Total Questions: 150
Format: Multiple Choice
Passing Score: 85%
Time Limit: 3 hours
Section 1: Physiology of Sleep (Questions 1–20)
1. Which stage of non-rapid eye movement (NREM) sleep is known as “slow-
wave sleep” and is essential for physical restoration?
A) N1
B) N2
C) N3
D) REM
Answer: C
*Rationale: N3 (slow-wave or delta sleep) is the deepest NREM stage, crucial
for tissue repair, growth hormone release, and energy restoration.*
2. REM sleep is characterized by:
A) Decreased brain activity
B) Paralysis of most voluntary muscles
C) Slow heart rate
D) No eye movements
Answer: B
Rationale: REM sleep involves rapid eye movements, vivid dreaming, and
skeletal muscle atonia (paralysis) except for diaphragm and extraocular
muscles.
,3. During a normal sleep cycle, REM sleep typically occurs:
A) Only once at the beginning of the night
B) Every 90–120 minutes, with longer duration toward morning
C) Only in the last 2 hours of sleep
D) Randomly without pattern
Answer: B
Rationale: Sleep cycles every 90–120 minutes; REM episodes lengthen as the
night progresses.
4. Which neurotransmitter promotes wakefulness?
A) Melatonin
B) GABA
C) Orexin (hypocretin)
D) Adenosine
Answer: C
Rationale: Orexin neurons stabilize wakefulness; deficiency causes
narcolepsy.
5. The suprachiasmatic nucleus (SCN) controls:
A) Muscle tone during REM
B) Circadian rhythms
C) Dream recall
D) Respiratory rate during sleep
Answer: B
Rationale: The SCN in the hypothalamus is the body’s master circadian
clock.
6. Melatonin secretion is inhibited by:
A) Darkness
B) Bright light
C) Warm bath
D) Exercise
Answer: B
Rationale: Light exposure suppresses pineal gland melatonin production.
7. Which stage of sleep has the lowest arousal threshold (easiest to wake)?
A) N1
,B) N2
C) N3
D) REM
Answer: A
Rationale: N1 is light sleep; people awaken easily.
8. Growth hormone is primarily secreted during:
A) REM sleep
B) N3 (slow-wave) sleep
C) N1 sleep
D) Wakefulness
Answer: B
Rationale: GH release peaks during N3 sleep.
9. Which statement about REM sleep is true?
A) Heart rate and blood pressure decrease to lowest levels
B) Thermoregulation is highly active
C) Brain oxygen consumption is higher than when awake
D) No dreaming occurs
Answer: C
Rationale: REM sleep is metabolically active; brain O₂ consumption
increases.
10. A patient who experiences sleepwalking is most likely in which stage?
A) REM
B) N1
C) N3
D) Transitional stage
Answer: C
*Rationale: Sleepwalking (somnambulism) occurs during N3 slow-wave
sleep.*
11. The average length of one complete sleep cycle (N1→N2→N3→N2→REM)
is:
A) 30 minutes
B) 60 minutes
C) 90–110 minutes
, D) 180 minutes
Answer: C
Rationale: Typical cycle length is 90–110 minutes in adults.
12. Which hormone helps induce sleep?
A) Cortisol
B) Adrenaline
C) Adenosine
D) Norepinephrine
Answer: C
Rationale: Adenosine accumulates during wakefulness and promotes sleep
pressure.
13. In older adults, sleep architecture changes include:
A) Increased N3 sleep
B) Decreased REM latency
C) More time in N1 and N2, less N3
D) No change
Answer: C
*Rationale: Aging reduces slow-wave (N3) sleep and increases lighter sleep
stages.*
14. Circadian rhythm disruption is most likely in:
A) Day shift nurses
B) Rotating shift workers
C) Elderly in assisted living
D) School-aged children
Answer: B
Rationale: Rotating shifts disrupt light-dark cycle and sleep-wake timing.
15. Which brain structure is primarily responsible for transitioning between
sleep and wake?
A) Cerebellum
B) Basal ganglia
C) Reticular activating system (RAS)
D) Hippocampus