OCR SUMMER 2026
PREDICTED PAPER
AS Level Biology B (Advancing Biology)
H022/02 Biology in depth
Time allowed: 1 hour 30 minutes
You can use:
a scientific or graphical calculator
a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using acorrect method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 21 pages.
ADVICE
• Read each question carefully before you start your answer.
Turn over
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, 2
1 Figure 1.1 below shows the process of semi-conservative DNA replication.
Fig 1.1
(a) Name the enzyme that breaks the hydrogen bonds between complementary base
pairs during DNA replication and explain how it does so.
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.............................................................................................................................................. [2]
(b) The bases on one template strand of a DNA molecule are: ATTGGCCGTATGCGT
State the sequence of bases on the opposite strand.
...................................................................................................................................................
.............................................................................................................................................. [1]
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, 3
(c) Using Figure 1.1, explain why DNA replication is described as semi-conservative.
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(d) DNA polymerase only works in the 5'→3' direction, producing a leading strand and a
lagging strand.
Explain what happens on the lagging strand during replication, and name the
enzyme that joins the fragments together.
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.............................................................................................................................................. [3]
for more: tyrionpapers.com
PREDICTED PAPER
AS Level Biology B (Advancing Biology)
H022/02 Biology in depth
Time allowed: 1 hour 30 minutes
You can use:
a scientific or graphical calculator
a ruler (cm/mm)
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using acorrect method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 21 pages.
ADVICE
• Read each question carefully before you start your answer.
Turn over
for more: tyrionpapers.com
, 2
1 Figure 1.1 below shows the process of semi-conservative DNA replication.
Fig 1.1
(a) Name the enzyme that breaks the hydrogen bonds between complementary base
pairs during DNA replication and explain how it does so.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
.............................................................................................................................................. [2]
(b) The bases on one template strand of a DNA molecule are: ATTGGCCGTATGCGT
State the sequence of bases on the opposite strand.
...................................................................................................................................................
.............................................................................................................................................. [1]
for more: tyrionpapers.com
, 3
(c) Using Figure 1.1, explain why DNA replication is described as semi-conservative.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
.............................................................................................................................................. [2]
(d) DNA polymerase only works in the 5'→3' direction, producing a leading strand and a
lagging strand.
Explain what happens on the lagging strand during replication, and name the
enzyme that joins the fragments together.
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
...................................................................................................................................................
.............................................................................................................................................. [3]
for more: tyrionpapers.com
