[Pharmacology FINAL Prototype Drugs]
Pharmacology FINAL Prototype Drugs
Study online at https://quizlet.com/_d7odc9
1. Opioid agonist morphine
2. Opioid agonist MOA: binds to mu and kappa receptors to provide analge-
sia
Primary use:
- analgesia
- anesthesia
3. Opioid agonist Adverse effects:
- respiratory depression
- sedation
- N&V
- dysphoria
- hallucinations
- itching sensation
- pruritus
- constipation
- drowsiness
- dizziness
- anaphylactoid reaction
- cardiac arrest
- convulsions
- potential abuse
- tolerance
Contraindications:
- gallbladder disease
- acute or severe asthma
- GI obstruction
- severe hepatic or renal impairment
4. Opioid antagonist naloxone (Narcan)
4/16/2026, 4:58:38 PM 4/16/2026,:58:36 PM 4/16/2026, 4:58:34 PM
, [Pharmacology FINAL Prototype Drugs]
Pharmacology FINAL Prototype Drugs
Study online at https://quizlet.com/_d7odc9
5. Opioid antagonist MOA: blocks mu and kappa receptors
Primary use: reverse respiratory depression due to opioid
use
6. Opioid antagonist Adverse effects:
- withdrawal symptoms
- muscle and joint pain
- sleep anxiety
- headache
- nervousness
- N&V
- insomnia
- increased BP
Contraindications:
- nonopioid medication caused respiratory depression
7. NSAIDs ibuprofen (Mortin, Advil)
8. NSAIDs MOA: inhibits COX-1 and COX-2, preventing the formation
of prostaglandins
Primary use:
- mild-moderate pain
- reduce inflammation
9. NSAIDs Adverse effects:
- GI upset
- acute renal failure
- nausea
- heartburn
- epigastric pain
- dizziness
- GI ulceration with occult/gross bleeding
- cardiovascular risk
4/16/2026, 4:58:38 PM 4/16/2026,:58:36 PM 4/16/2026, 4:58:34 PM
, [Pharmacology FINAL Prototype Drugs]
Pharmacology FINAL Prototype Drugs
Study online at https://quizlet.com/_d7odc9
Contraindications:
- perioperative pain for CABG surgery
- peptic ulcers
- renal or hepatic impairment
- NSAID/aspirin caused nasal polyps, angioedema, or
bronchospasm
- use cautiously in pts with HF, HTN, stroke hx, or MI hx
10. Salicylates aspirin (ASA)
11. Salicylates MOA: inhibits prostaglandin synthesis and causes vasodi-
lation on peripheral blood vessels
Primary use:
- anticoagulant
- antipyretic
- anti-inflammatory
- analgesic
12. Salicylates Adverse effects:
- GI distress and bleeding
- tinnitus/ototoxicity
Contraindications:
- children under 18 years of age
- pts on anticoagulant therapy (e.g. warfarin or heparin)
13. Antipyretics acetaminophen (Tylenol)
14. Antipyretics MOA: treats fever at the hypothalamus and allows for
sweating and heat dissipation without affecting platelet
aggregation, cardiotoxicity, or GI bleeding
Primary use:
- reduce fever
4/16/2026, 4:58:38 PM 4/16/2026,:58:36 PM 4/16/2026, 4:58:34 PM
, [Pharmacology FINAL Prototype Drugs]
Pharmacology FINAL Prototype Drugs
Study online at https://quizlet.com/_d7odc9
- pain relief
- (doesn't relieve inflammation)
15. Antipyretics Adverse effects:
- liver damage/toxicity
- N&V
- chills
- abdominal discomfort
- fatal hepatic necrosis
Contraindications:
- malnourishment
- chronic alcoholism
- hypersensitivity
16. Triptans sumatriptan (Imitrex)
17. Triptans MOA: acts as a serotonin agonist and constricts some
intracranial blood vessels
Primary use: aborting migraines with or without auras
18. Triptans Adverse effects:
- GI upset
- dizziness
-drowsiness
- warming sensation
Contraindications:
- recent MIs
- angina pectoris
- HTN
- diabetes
- renal or hepatic impairment
19. Corticosteroid prednisone (Meticorten)
4/16/2026, 4:58:38 PM 4/16/2026,:58:36 PM 4/16/2026, 4:58:34 PM
Pharmacology FINAL Prototype Drugs
Study online at https://quizlet.com/_d7odc9
1. Opioid agonist morphine
2. Opioid agonist MOA: binds to mu and kappa receptors to provide analge-
sia
Primary use:
- analgesia
- anesthesia
3. Opioid agonist Adverse effects:
- respiratory depression
- sedation
- N&V
- dysphoria
- hallucinations
- itching sensation
- pruritus
- constipation
- drowsiness
- dizziness
- anaphylactoid reaction
- cardiac arrest
- convulsions
- potential abuse
- tolerance
Contraindications:
- gallbladder disease
- acute or severe asthma
- GI obstruction
- severe hepatic or renal impairment
4. Opioid antagonist naloxone (Narcan)
4/16/2026, 4:58:38 PM 4/16/2026,:58:36 PM 4/16/2026, 4:58:34 PM
, [Pharmacology FINAL Prototype Drugs]
Pharmacology FINAL Prototype Drugs
Study online at https://quizlet.com/_d7odc9
5. Opioid antagonist MOA: blocks mu and kappa receptors
Primary use: reverse respiratory depression due to opioid
use
6. Opioid antagonist Adverse effects:
- withdrawal symptoms
- muscle and joint pain
- sleep anxiety
- headache
- nervousness
- N&V
- insomnia
- increased BP
Contraindications:
- nonopioid medication caused respiratory depression
7. NSAIDs ibuprofen (Mortin, Advil)
8. NSAIDs MOA: inhibits COX-1 and COX-2, preventing the formation
of prostaglandins
Primary use:
- mild-moderate pain
- reduce inflammation
9. NSAIDs Adverse effects:
- GI upset
- acute renal failure
- nausea
- heartburn
- epigastric pain
- dizziness
- GI ulceration with occult/gross bleeding
- cardiovascular risk
4/16/2026, 4:58:38 PM 4/16/2026,:58:36 PM 4/16/2026, 4:58:34 PM
, [Pharmacology FINAL Prototype Drugs]
Pharmacology FINAL Prototype Drugs
Study online at https://quizlet.com/_d7odc9
Contraindications:
- perioperative pain for CABG surgery
- peptic ulcers
- renal or hepatic impairment
- NSAID/aspirin caused nasal polyps, angioedema, or
bronchospasm
- use cautiously in pts with HF, HTN, stroke hx, or MI hx
10. Salicylates aspirin (ASA)
11. Salicylates MOA: inhibits prostaglandin synthesis and causes vasodi-
lation on peripheral blood vessels
Primary use:
- anticoagulant
- antipyretic
- anti-inflammatory
- analgesic
12. Salicylates Adverse effects:
- GI distress and bleeding
- tinnitus/ototoxicity
Contraindications:
- children under 18 years of age
- pts on anticoagulant therapy (e.g. warfarin or heparin)
13. Antipyretics acetaminophen (Tylenol)
14. Antipyretics MOA: treats fever at the hypothalamus and allows for
sweating and heat dissipation without affecting platelet
aggregation, cardiotoxicity, or GI bleeding
Primary use:
- reduce fever
4/16/2026, 4:58:38 PM 4/16/2026,:58:36 PM 4/16/2026, 4:58:34 PM
, [Pharmacology FINAL Prototype Drugs]
Pharmacology FINAL Prototype Drugs
Study online at https://quizlet.com/_d7odc9
- pain relief
- (doesn't relieve inflammation)
15. Antipyretics Adverse effects:
- liver damage/toxicity
- N&V
- chills
- abdominal discomfort
- fatal hepatic necrosis
Contraindications:
- malnourishment
- chronic alcoholism
- hypersensitivity
16. Triptans sumatriptan (Imitrex)
17. Triptans MOA: acts as a serotonin agonist and constricts some
intracranial blood vessels
Primary use: aborting migraines with or without auras
18. Triptans Adverse effects:
- GI upset
- dizziness
-drowsiness
- warming sensation
Contraindications:
- recent MIs
- angina pectoris
- HTN
- diabetes
- renal or hepatic impairment
19. Corticosteroid prednisone (Meticorten)
4/16/2026, 4:58:38 PM 4/16/2026,:58:36 PM 4/16/2026, 4:58:34 PM
