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Terms in this set (34)
Causes widespread physiological The main objective in any pharmacotherapeutic plan
changes is to select drugs that achieve all of the following,
except which one of the following?
ACE inhibitor drugs bind to and block Some drugs work by interacting directly with a
the action of an angiotensin- specific molecular enzyme target in a cell or a body
converting enzyme which inhibits the fluid to decrease its action. Which one of the
formation of angiotensin II following examples would be a drug-enzyme
interaction?
Helps identify genetic factors Which one of the following best describes the
responsible for variable drug purpose of pharmacogenomics?
responses in an individual
Hepatic first-pass effect Which one of the following processes explains why
the recommended oral dose of some medications is
much higher than the parenteral dose of the same
medication?
Absorption The component of pharmacokinetics by which drug
molecules move from their administration site across
one or more cell membranes to enter the blood.
fat soluble Drugs that easily cross the lipid cell membrane are
called?
infants When prescribing for this population, the NP
understands that drugs administered topically will be
absorbed faster.
, a diagnosis Before prescribing medication(s) to a patient, the NP
should always begin with which one of the following?
- a person with chronic kidney disease Which three of the following reflect a clinical
stage III-IV situation in which a patient is at increased risk for an
- adult with a BMI of 17 adverse drug reaction
- 87 y/o female
intrinsic adverse drug reaction The NP prescribes lisinopril 10 mg daily for
hypertension and instructs the patient to keep a daily
blood pressure log to monitor response. The patient
calls 3 days later reporting fatigue, lightheadedness
and blood pressure of 90/50. Based on what you
know about the drugs pharmacodynamic actions, this
would be considered what type of adverse drug
reaction?
tolerance An adverse drug reaction characterized by a
decreased response to a particular drug dosage
when the drug is given repeatedly over time is
called?
Toxic reaction You are called to a rapid response on a post-
operative patient who has been receiving
meperidine (Demerol) every 6 hours for pain. The
patient's respirations are shallow, requiring bag-mask
assistance. You suspect this is a response to the
meperidine. What type of intrinsic adverse reaction
would this be classified as?
teratogenic An adverse reaction in which a drug causes
malformations in a developing fetus is called?
heart rate x stroke volume x total Which one of the following formula is used for
peripheral vascular resistance determining blood pressure?