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NR565 Week 5 Focus: Thyroid, Diabetes, Asthma, & Smoking Cessation – Q&A Bank

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Master Week 5 of NR565 with confidence! This focused question bank drills down on the most testable topics: hypothyroidism vs. hyperthyroidism, thyroid medication monitoring (levothyroxine, methimazole, PTU), insulin calculations (TDD, carbohydrate ratios), diabetes drug classes (metformin, sulfonylureas, SGLT2 inhibitors), asthma step-therapy, and smoking cessation pharmacotherapy (varenicline, bupropion, nicotine replacements). Each of the 150+ questions includes a verified, in-depth answer to solidify your clinical reasoning. If you want to conquer the endocrine and respiratory sections of your midterm or final, this resource is a must-have.

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NR565 week 5 2026/2027 BANK QUESTIONS WITH
DETAILED VERIFIED ANSWERS / EXAM QUESTIONS
WILL COME FROM HERE (100% CORRECT ANSWERS/ A+
GRADED



Signs and symptoms of hypothyroidism and hyperthyroidism -
ANSWERS--Hypothyroidism:
Thick, coarse, dry Hyporeflexia, "hung up" patella reflex Slow thought
process, Weight gain (5-10 lbs./2.25-4.5 kg) Constipation,
Menorrhagia, Cold intolerance: Cold all the time


Hyperthyroidism (aka graves disease):
Smooth, silky Hyperreflexia, Mind racing, Weight loss (10 lbs./4.5 kg)
Diarrhea, loose, frequent stools, Oligomenorrhea, Heat intolerance:
Hot all the time


pg. 418-419


What adjunctive therapy is good to prescribe to control symptoms of
hyperthyroidism other than thyroid specific medications?
Know drug classes and examples of those drug classes. - ANSWERS--
β-Blockers and nonradioactive iodine may be used as adjunctive
therapy. β-Blockers suppress tachycardia by blocking β-receptors on
the heart. Nonradioactive iodine inhibits synthesis and release of
thyroid hormones.

,2|Page


pg. 419


Monitoring needs and intervals for thyroid medications. – ltw1
- Propylthiouracil (PTU) carries a risk for liver toxicity. Although rare,
the FDA recommends against using PTU as a first-line treatment due
to potential for hepatic toxicity. - ANSWERS--Treatment continues
for 1-2 years
PTU has caused rare cases of liver injury. Onset is sudden and
progression is rapid. pg 421


- Effects of maternal hypothyroidism on offspring and appropriate
patient teaching related to need for treatment. - ANSWERS--
Maternal hypothyroidism can result in permanent
neuropsychological deficits in the child.


can decrease IQ and other aspects of neuropsychological function in
the child.


teaching:
to help ensure healthy fetal development, maternal hypothyroidism
must be diagnosed and treated very early.


some authorities currently recommend routine screening for
hypothyroidism as soon as pregnancy is confirmed. If hypothyroidism
is diagnosed, replacement therapy should begin immediately.

,3|Page


the signs and symptoms of pregnancy mimics those of
hypothyroidism


When women taking thyroid supplements become pregnant, dosage
requirements usually increase—often by as much as 50%. The need
for increased dosage begins between weeks 4 and 8 of gestation,
levels off at approximately week 16, and then remains steady until
parturition.


pg. 418


- Patient teaching for thyroid medications. - ANSWERS--
:levothyroxine:
should be taken on an empty stomach in the morning, at least 30 to
60 minutes before breakfast.


Inform patients about the symptoms of thyrotoxicosis and instruct
them to notify the prescriber if these develop (Sweating, irritability,
weight loss, tachycardia)Instruct patients to separate administration
of levothyroxine and these drugs by 4 hours


Overdose may cause thyrotoxicosis. Symptoms include tachycardia,
angina, tremor, nervousness, insomnia, sweating, and heat
intolerance.


methamizole:

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Agranulocytosis: Inform patients about early signs of agranulocytosis,
including fever or sore throat. If follow-up blood tests reveal
leukopenia, methimazole should be stopped.
Hypothyroidism: Methimazole may cause excessive reductions in
thyroid hormone synthesis. If signs of hypothyroidism develop or if
plasma levels of T3 and T4 become subnormal, dosage should be
reduced.


Radioactive Iodine:
Inform patients about symptoms of iodism, including brassy taste,
burning sensations in the mouth, and soreness of gums and teeth.
Iodine can also cause corrosive injury to the GI tract. Instruct
patients to notify the prescriber if severe abdominal distress
develops.


PTU:
can cause rare cases of liver injury


What drug class can interfere with the assessment and monitoring of
diabetes and why?
o You will need connect pathophysiology information of medications
and diabetes together. Think about alpha and beta cells. - ANSWERS-
-Hypoglycemic agents.
Drugs that lower blood glucose levels can intensify hypoglycemia
induced by insulin. Among these drugs are sulfonylureas, glinides,
and alcohol (used acutely or long term in excessive doses). When
these drugs are combined with insulin, special care must be taken to
ensure as best as possible that blood glucose does not fall too low.

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