Questions and Answers with Complete A+
Solutions 100% Correct (Clinical Pearls on
Hypertension, Infectious Disease,
Endocrinology, Dermatology, OB/GYN, and
More)
What mood d/o causes depressive symptoms occurring at a specific time of year with full
remission in between episodes, which usually occur during fall and winter months. - Correct
Answer -Seasonal affective disorder (SAD).
- Criteria specify that full remission must occur when the specific season ends and there must
be at least two consecutive years of mood episodes.
- Risk factors include family history, living at a more northern latitude, female sex, and age 18-
30.
- Pt w/ regular recurrences, long term preventive intervention each yr w/ light therapy starting
in the early fall is indicated.
Which of the following anti-HTN most likely causes hyperkalemia?
A) Amlodipine
B) Chlorthalidone
C) Hydrochlorothiazide
D) Metoprolol
,E) Olmesartan - Correct Answer -E) Olmesartan.
- Hyperkalemia is a known side effect of ACEi and ARB.
- Risk of hyperK increased with CKD, DM, moderately severe to severe HF, NSAID use, older
adults.
- Chlorthalidone and HCTZ can cause hypokalemia. Amlodipine and metoprolol have no
significant effect on potassium.
Obese 40yo F, w/ DM, present w/ painful deep-seated nodules in both axillae w/ purulent
drainage and associate scarring. Dx? - Correct Answer -Crohn's disease
Hidradenitis suppurativa is associated with what conditions? - Correct Answer -- Diabetes
- Obesity
- Crohn dz
- Arthritis/ spondyloarthropathy
- PCOS
- Metabolic syndrome
- Pyoderma gangrenosum
- Down Syndrome
3 stages of HS:
- Stage I: single/ multiple abscesses w/o sinus tracts or scarring.
- Stage II: abscess recurrence w/ sinus tracts and scarring and widely spreaded lesions.
- Stage III: diffuse abscess with interconnecting sinus tracts.
, Dermatitis herpetiformis (clusters of pruritic lesions) is associated with what condition? -
Correct Answer -Celiac disease.
when to use omalizumab for asthma? - Correct Answer -Severe type 2 inflammatory asthma
poorly controlled with optimal therapy with long term medication, including high-dose
corticosteroids and long acting B agonist.
- According GINA guidelines, Management of severe asthma includes determination of the
asthma phenotype to assess for type 2 inflammation.
- Type 2 asthma includes allergic and eosinophilic asthma. (Elevated serum eosinophils, elevated
fractional exhaled nitric oxide).
- Non-type 2 asthma is driven by neutrophils and is associated with smoking and obesity.
Patient at 36 weeks gestation has itchiness in palms and soles. Next step? - Correct Answer -
Check bile acid levels.
- Intrahepatic cholestasis of pregnancy (ICP): pruritus of palms/soles with or without jaundice,
elevated serum bile acid. MC in late 2nd and/or 3rd trimester. Can cause significant risk to the
fetus, including fetal death. Treated aggressively with ursodeoxycholic acid and often early
delivery.
Best Evidence based treatment for Frailty syndrome?
A) Protein supplements