UT Tyler Pharm Final (tests 1-3) Exam
Questions & Answers (Grade A+)
Pharmakinetics -
correct answer ✅process of drug movement to achieve drug
action; absorption, distribution, metabolism (biotransformation),
and excretion
Absorption -
correct answer ✅movement of drug particles from GI tract to body
fluids; passive or active
Passive Absorption -
correct answer ✅diffusion; movement from high to low
concentration; energy not required
Active Absorption -
correct answer ✅carrier such as enzyme or protein used to move
drug against a concentration gradient
Pinocytosis -
correct answer ✅process by which cells carry a drug across their
membrane by engulfing drug particles
,UT Tyler Pharm Final (tests 1-3) Exam
Questions & Answers (Grade A+)
Bioavailability -
correct answer ✅percentage of administered drug dose that
reaches the systemic circulation; after absorption and first-pass
metabolism
Affected by:
1) drug form 2) route of admin 3) GI mucosa and motility 4) food
and other drugs 5) changes in liver metabilism or inadequate
hepatic flow
Distribution -
correct answer ✅process by which the drug becomes available to
body fluids and body tissues
Affected by:
1) blood flow 2) drug's affinity to tissue 3) protein binding effect
Protein Binding -
correct answer ✅portion of drug that is bound is inactive b/c it is
unavailable to receptors; portion that remains unbound is free,
active drug (only free drugs cause pharmacologic response)
,UT Tyler Pharm Final (tests 1-3) Exam
Questions & Answers (Grade A+)
Metabolism -
correct answer ✅process by which body inactivates or
biotransforms drugs; liver is primary site
Elimination -
correct answer ✅kidneys (mainly), bile, feces, lungs, saliva, sweat,
and breat milk
Half-Life -
correct answer ✅time it takes for one half of drug concentratio to
be emliminated
Additive Effect -
correct answer ✅when two drugs of similar action are
administered; sum of the effects of two drugs
Synergistic Effect -
correct answer ✅when two or more drugs are given together, one
drug can potentiate the other; clinical effect is substantially greater
than the combined effect of the two
, UT Tyler Pharm Final (tests 1-3) Exam
Questions & Answers (Grade A+)
Antagonist Effect -
correct answer ✅when two drugs have opposite effects; each drug
cancels out the effect of the other
Drug-Food Interaction -
correct answer ✅may increase, decrease, or delay drug absorption
Ethical principles related to med admin -
correct answer ✅respect to persons, beneficence, justice, and
veracity
Autonomy -
correct answer ✅right to self determination; patient can refuse
any and all treatments
Beneficence -
correct answer ✅duty to do good and not harm to others; to
maximize benefits and minimize possible harm that right that might
occur in research
Justice -
correct answer ✅requires all people to be treated fairly; equal
Questions & Answers (Grade A+)
Pharmakinetics -
correct answer ✅process of drug movement to achieve drug
action; absorption, distribution, metabolism (biotransformation),
and excretion
Absorption -
correct answer ✅movement of drug particles from GI tract to body
fluids; passive or active
Passive Absorption -
correct answer ✅diffusion; movement from high to low
concentration; energy not required
Active Absorption -
correct answer ✅carrier such as enzyme or protein used to move
drug against a concentration gradient
Pinocytosis -
correct answer ✅process by which cells carry a drug across their
membrane by engulfing drug particles
,UT Tyler Pharm Final (tests 1-3) Exam
Questions & Answers (Grade A+)
Bioavailability -
correct answer ✅percentage of administered drug dose that
reaches the systemic circulation; after absorption and first-pass
metabolism
Affected by:
1) drug form 2) route of admin 3) GI mucosa and motility 4) food
and other drugs 5) changes in liver metabilism or inadequate
hepatic flow
Distribution -
correct answer ✅process by which the drug becomes available to
body fluids and body tissues
Affected by:
1) blood flow 2) drug's affinity to tissue 3) protein binding effect
Protein Binding -
correct answer ✅portion of drug that is bound is inactive b/c it is
unavailable to receptors; portion that remains unbound is free,
active drug (only free drugs cause pharmacologic response)
,UT Tyler Pharm Final (tests 1-3) Exam
Questions & Answers (Grade A+)
Metabolism -
correct answer ✅process by which body inactivates or
biotransforms drugs; liver is primary site
Elimination -
correct answer ✅kidneys (mainly), bile, feces, lungs, saliva, sweat,
and breat milk
Half-Life -
correct answer ✅time it takes for one half of drug concentratio to
be emliminated
Additive Effect -
correct answer ✅when two drugs of similar action are
administered; sum of the effects of two drugs
Synergistic Effect -
correct answer ✅when two or more drugs are given together, one
drug can potentiate the other; clinical effect is substantially greater
than the combined effect of the two
, UT Tyler Pharm Final (tests 1-3) Exam
Questions & Answers (Grade A+)
Antagonist Effect -
correct answer ✅when two drugs have opposite effects; each drug
cancels out the effect of the other
Drug-Food Interaction -
correct answer ✅may increase, decrease, or delay drug absorption
Ethical principles related to med admin -
correct answer ✅respect to persons, beneficence, justice, and
veracity
Autonomy -
correct answer ✅right to self determination; patient can refuse
any and all treatments
Beneficence -
correct answer ✅duty to do good and not harm to others; to
maximize benefits and minimize possible harm that right that might
occur in research
Justice -
correct answer ✅requires all people to be treated fairly; equal
