TECHNICIAN. EXAM QUESTIONS AND
ANSWERS 100% PASS.
U.S. Government provides approximately how much in research/development funds spent by
college and university? - ANS 2/3
What information is important on grant applications to request funds? - ANS Detailed
description of research goals, scientific basis of study, and review of relevant literature and all
procedures to be performed
What is the difference between NIH & NSF? - ANS NIH: primary granting agency: academia,
federal agencies, biomedical research
NSF: Basic research in math, medicine, and biology
The USDA stands for what? - ANS United States Department of Agriculture
The USDA is responsible for what? - ANS Enforces and amends AWA
Auction, sale, exhibit, transport, breeding, or conduct of research with animals
Animals exempt from AWA
Research institutions mst register with
Supply annual reports
Inspection records through the FOIA
Unscheduled inspection once per year
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,What does the FOIA stand for? - ANS Freedom of Information Act - provides the USDA's
inspection records
What is the Public Health Service Policy? - ANS Institutions which receive funding from PHS
and NIH must follow these guidelines, requires filing of an Amimal Welfare Assurance document
that demonstrates the institution is following the Guid, PHS policy, AWA, and any other
applicable laws
The FDA has many responsibilites including: - ANS Assures that new drugs and medical
devices are safe and effective before approved for use in humans
Monitors drug approval
Includes human, and veterinary drugs, food, and medical devices
Requires that effectiveness be demonstrated through well controlled investigations
What is GLP? - ANS Good Laboratory Practices
Established in 1978 with implementation of laboratory audits and inspection programs
Details requirements for QA and SOPs
What is the importance of importation and transportations regulations? - ANS For the
protection of humans and environment from potential disease carrying organisms
Which agencies control importation? - ANS CDC, USDA, and US Fish & Wildlife Service
Institutional polices are established for: - ANS facility operations
care and use procedures
veterinary support
physical plant
Standard operating procedures relate to: - ANS wall aspects of animal care and support
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,personnel management
health surveillance of animals and personnel
equipment
investigators
What are the functions of IACUCs and who mandates? - ANS mandated by AWA, PHS policy,
and the Guide
Review and approve protocols for animal use
Review animal use program and perform animal facilities inspections at least every 6 months
What has to happen before animal research can begin? - ANS principal investigator provides
written details of how animals will be used in the research project
IACUC must review all protocols using animals and must approve all protocols before any animal
research can begin
What does the IACUC determine? - ANS Can deny permission ro start a project
can stop a research peoject
Ensures compliance with regulations
Reviews complete protocols at least every 3 years; reviews updates to protocols yearly
What is the AAALAC, International? - ANS Association for Assessment and Accreditation of
Laboratory Animal Care, International
Non-profit organization that provides a mechanism for peer review of animal care and use
programs by scientific community
Detailed application with information on facilities, procedures, programs, and research animals
to use
Annual report must be submitted to AAALAC on status of animal care program
Site inspection and program evaluation every 3 years
Why is it important to keep accurate, up-to-date records? - ANS Determine if procedures are
followed according to established standards
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, Determine whether environmental controls are properly maintained
Improve facility efficiency and effectivness
What is PHS Policy? - ANS All assurance records related directly to grant applications,
research proposals, and changes of research activities > 3yrs after completion
Centralized - ANS Serves all the institution's animal care needs; 1 director for entire
institution; All personnel associated with the animal facility; All other purchases, per diem,
depreciation, inventories, operational costs, and supplies
Decentralized - ANS Each department has own animal facility and operating budget; each
department has own animals, supplies, equipment and animal care staffing
Direct costs - ANS Salaries, fringe benefits, equipment, supplies, and operational exprenses
(depend on # animals being housed)
Indirect Costs - ANS physical plant, energy costs, depreciation, heating rooms
Cost Centers - ANS Cage washing, laboratory services
Why is cost accounting important? - ANS Individulal costs used for projecting future cost;
comparisons reveal areas in which costs can be reduced; per diem components (expense to
maintain 1 animal for 1 day)
Calculating per diem charges - ANS Internal direct costs are incurred for the husbandry of
animals and for other services provided by the animal facility for the benefits of special projects
If total costs of maintaining a colony of cats is $27,375 over a 1 year period and the average
daily census is 25 cats, what is the per diem charge needed to recover these costs? -
ANS Divide $27,375 by 365 and multiply the result by 25 = 3.00
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