QUESTIONS AND CORRECT ANSWERS
Which of the following terms describes the step at which cells become irreversibly committed to a
particular cell fate?
- Differentiation
- Specification
- Gastrulation
- Determination - CORRECT ANSWER - Determination
"the second and irreversible step of commitment"
"cells capable of differentiating into their fate when placed in an environment that is actively
supporting a different fate"
ex: if a cell determined for 'muscle' is placed amongst cells determined to be 'neurons', then the
determined muscle cell will still follow its fate and become a muscle cell; despite the surrounding
environment
Which of the following is the correct order of developmental steps leading to a specialized cell type?
- Differentiation, specification, determination
- Differentiation, determination, specification
- Determination, specification, differentiation
- Specification, determination, differentiation
- Determination, differentiation, specification - CORRECT ANSWER - Specification,
determination, differentiation
Step 1 : COMMITMENT - the cell's developmental fate has been restricted (@ gene expression level)