CMN 548 UNIT 5 EXAM QUESTIONS
WITH CORRECT SOLUTIONS|| 100%
GUARANTEED PASS|| UPDATED
2026/2027 SYLLABUS||ALREADY
GRADED A+||<<RECENT VERSION>>
What are the indications for use of venlafaxine (Effexor) and desvenlafaxine
(Pristiq)? - ANSWER ✓ desvenlafaxine (Pristiq): FDA approved ONLY for MDD
venlafaxine (Effexor): approved for MDD, GAD, social anxiety, panic disorder
What is the incidence rate of sexual SE for venlafaxine (Effexor) and
desvenlafaxine (Pristiq)? - ANSWER ✓ exceed 30-40%
sexual SE include decreased libido + delayed orgasm or ejaculation
What are the discontinuation syndrome symptoms of venlafaxine (Effexor) and
desvenlafaxine (Pristiq)? - ANSWER ✓ dizziness
dry mouth
insomnia
nausea
nervousness
sweating
anorexia
diarrhea
somnolence
sensory disturbances
what are the therapeutic indications for duloxetine (Cymbalta)? - ANSWER ✓
Duloxetine (cymbalta) is indicated for
-Depression
-neuropathy pain associated w/diabetes
What sets levomilnacipran apart from other SNRIs? - ANSWER ✓ treats MDD in
adults
,-it has greater potency for NE reuptake inhibition than for serotonin reuptake
inhibition and does not directly affect the uptake of dopamine or other
neurotransmitters.
-Taken once daily as a SR formula
What are the clinical indications for trazodone? - ANSWER ✓ -MDD
-Insomnia
-ED
-@ low doses, can control severe agitation in children w/developmental d/o or
elderly with dementia
-GAD at higher doses (250mg/day)
-depression in pts with schizophrenia
-reducing nightmares in those with PTSD
Discuss the possible complications of taking trazodone concurrently with an
antihypertensive? - ANSWER ✓ orthostatic hypotension 4-6 hrs after dose is
taken.
What are the s/s of OD on trazodone? What is the tx for OD? - ANSWER ✓
lethargy, vomiting, drowsiness, HA, orthostasis, dizziness, dyspnea, tinnitus,
myalgias, tachycardia, incontinence, shivering, coma
TX: emesis or gastric lavage + supportive care.
Forced diuresis may enhance elimination
Discuss Trazodone induced priapism: when would it occur? At what dose?
indications for d/c ing trazodone? - ANSWER ✓ causes priapism in 1 : 10,000
men
usually appears in the first 4 weeks of tx but may also occur as late as 18 months
into tx. It can appear at any dose. Trazodone should be immediately discontinued.
Trazodone can INCREASE the plasma concentration of ______ and _______? -
ANSWER ✓ Digoxin and phenytoin
What are the indications for nefazodone? - ANSWER ✓ MDD
panic d/o
GAD
premenstrual dysphoric d/o
chronic pain
PTSD
, chronic fatigue syndrome
A pt reports SE of "visual trails". What does this mean? - ANSWER ✓ Visual
trails: seeing an after image when looking at moving objects or when moving one's
head quickly
Monitor what lab d/t safety concerns with the use of nefazodone? - ANSWER ✓
serial hepatic function test
What are the clinical indications for mirtazapine? - ANSWER ✓ Depression
augmentation of antidepressants
counteract serotonergic SE
What are the TWO characteristic SE of mirtazapine? - ANSWER ✓
INCREASED appetite and sedation
What are the most common AE of mirtazapine? - ANSWER ✓ somnolence
Monitoring of WBCs for pts who develop signs of infection is needed as
mirtazapine is associated with _____ and ___________? - ANSWER ✓ -febrile
neutropenia
-agranulocytosis
What are the symptoms of discontinuation syndrome with abrupt withdrawal of
mirtazapine? When would this most likely occur? How long does this typically
last? - ANSWER ✓ dizziness, lethargy, N/V/D, HA, fever, sweating, chills,
malaise, incoordination, insomnia, vivid dreams, myalgia, paresthesias,
dyskinesias, "electric shock like sensations" visual discoordination, anxiety,
irritability, confusion, slow thinking, hypomania, depersonalization
-most likely occur within 1-7 days after drug stopped. Typically disappears within
3 weeks
Bupropion (Wellbutrin) action? - ANSWER ✓ bupropion inhibits the reuptake of
NE and at higher doses, DA. This class of medication does not act upon the 5-HT
system.
-MOA may involve the presynaptic release of NE and DA
What are the therapeutic indications for bupropion? - ANSWER ✓ depression
WITH CORRECT SOLUTIONS|| 100%
GUARANTEED PASS|| UPDATED
2026/2027 SYLLABUS||ALREADY
GRADED A+||<<RECENT VERSION>>
What are the indications for use of venlafaxine (Effexor) and desvenlafaxine
(Pristiq)? - ANSWER ✓ desvenlafaxine (Pristiq): FDA approved ONLY for MDD
venlafaxine (Effexor): approved for MDD, GAD, social anxiety, panic disorder
What is the incidence rate of sexual SE for venlafaxine (Effexor) and
desvenlafaxine (Pristiq)? - ANSWER ✓ exceed 30-40%
sexual SE include decreased libido + delayed orgasm or ejaculation
What are the discontinuation syndrome symptoms of venlafaxine (Effexor) and
desvenlafaxine (Pristiq)? - ANSWER ✓ dizziness
dry mouth
insomnia
nausea
nervousness
sweating
anorexia
diarrhea
somnolence
sensory disturbances
what are the therapeutic indications for duloxetine (Cymbalta)? - ANSWER ✓
Duloxetine (cymbalta) is indicated for
-Depression
-neuropathy pain associated w/diabetes
What sets levomilnacipran apart from other SNRIs? - ANSWER ✓ treats MDD in
adults
,-it has greater potency for NE reuptake inhibition than for serotonin reuptake
inhibition and does not directly affect the uptake of dopamine or other
neurotransmitters.
-Taken once daily as a SR formula
What are the clinical indications for trazodone? - ANSWER ✓ -MDD
-Insomnia
-ED
-@ low doses, can control severe agitation in children w/developmental d/o or
elderly with dementia
-GAD at higher doses (250mg/day)
-depression in pts with schizophrenia
-reducing nightmares in those with PTSD
Discuss the possible complications of taking trazodone concurrently with an
antihypertensive? - ANSWER ✓ orthostatic hypotension 4-6 hrs after dose is
taken.
What are the s/s of OD on trazodone? What is the tx for OD? - ANSWER ✓
lethargy, vomiting, drowsiness, HA, orthostasis, dizziness, dyspnea, tinnitus,
myalgias, tachycardia, incontinence, shivering, coma
TX: emesis or gastric lavage + supportive care.
Forced diuresis may enhance elimination
Discuss Trazodone induced priapism: when would it occur? At what dose?
indications for d/c ing trazodone? - ANSWER ✓ causes priapism in 1 : 10,000
men
usually appears in the first 4 weeks of tx but may also occur as late as 18 months
into tx. It can appear at any dose. Trazodone should be immediately discontinued.
Trazodone can INCREASE the plasma concentration of ______ and _______? -
ANSWER ✓ Digoxin and phenytoin
What are the indications for nefazodone? - ANSWER ✓ MDD
panic d/o
GAD
premenstrual dysphoric d/o
chronic pain
PTSD
, chronic fatigue syndrome
A pt reports SE of "visual trails". What does this mean? - ANSWER ✓ Visual
trails: seeing an after image when looking at moving objects or when moving one's
head quickly
Monitor what lab d/t safety concerns with the use of nefazodone? - ANSWER ✓
serial hepatic function test
What are the clinical indications for mirtazapine? - ANSWER ✓ Depression
augmentation of antidepressants
counteract serotonergic SE
What are the TWO characteristic SE of mirtazapine? - ANSWER ✓
INCREASED appetite and sedation
What are the most common AE of mirtazapine? - ANSWER ✓ somnolence
Monitoring of WBCs for pts who develop signs of infection is needed as
mirtazapine is associated with _____ and ___________? - ANSWER ✓ -febrile
neutropenia
-agranulocytosis
What are the symptoms of discontinuation syndrome with abrupt withdrawal of
mirtazapine? When would this most likely occur? How long does this typically
last? - ANSWER ✓ dizziness, lethargy, N/V/D, HA, fever, sweating, chills,
malaise, incoordination, insomnia, vivid dreams, myalgia, paresthesias,
dyskinesias, "electric shock like sensations" visual discoordination, anxiety,
irritability, confusion, slow thinking, hypomania, depersonalization
-most likely occur within 1-7 days after drug stopped. Typically disappears within
3 weeks
Bupropion (Wellbutrin) action? - ANSWER ✓ bupropion inhibits the reuptake of
NE and at higher doses, DA. This class of medication does not act upon the 5-HT
system.
-MOA may involve the presynaptic release of NE and DA
What are the therapeutic indications for bupropion? - ANSWER ✓ depression
