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Titration of insulin dosage is based on self blood glucose monitoring. The more
complex the regime, the most frequent monitoring needs to be done (up to __-___x
day) - ANSWER ✓ 4-6
All patients should get a Rx for _________ injection for treatment of severe
hypoglycemia - ANSWER ✓ Glucagon
Patients should be encouraged to wear a ____________ ___________ - ANSWER
✓ medic-alert bracelet
Usual Total daily dose of insulin can range from _____->_____ units/kg
depending on diet, exercise, degree of insulin resistance, oral medications, and beta
cell functioning - ANSWER ✓ 0.2->1.5
Most insulin comes in ____ml vials - ANSWER ✓ 10
Type 1 diabetics are best managed with multiple daily injections of _______ or
______-acting insulin to cover meals and ______ or ______ daily long-acting
basal insulin - ANSWER ✓ rapid or short
once or twice
The most physiologic regime involves titration of insulin based on ______
_________ and __________ _________ - ANSWER ✓ carb counting
correction factor
, What is the most common regime when starting a T2DM on insulin? What does it
involve? - ANSWER ✓ basal insulin regime; once daily injection of levemir or
lantus usually at bedtime
What is the starting dose for patients on basal insulin regime of lantus or levemir?
- ANSWER ✓ 10 units
Patients starting a basal insulin regime should titrate up __ units every __ days
until they reach their fasting blood glucose goal (usually ___-_____ mg/dL) -
ANSWER ✓ 3; 3; 80-120
Type 2 diabetics starting a basal insulin regime should also continue what med? -
ANSWER ✓ insulin sensitizers like Metformin.
Sulfonylureas may be continued when initiating a basal insulin regime at the same
dose initially or reduced by ___%, especially if _______ develops - ANSWER ✓
50; hypoglycemia
Thiazolidinediones may be continued when starting a basal insulin regime, but can
result in _________ _________ and __________, so diet and exercise are
important - ANSWER ✓ increased weight gain and edema
________ is approved for use with Lantus. ________ is approved for use with any
basal insulin. ________ are not approved for use with insulin - ANSWER ✓
Byetta; Victosa, Bydureon
Basal insulin is usually dosed once a day, but can be given twice daily (am and
bedtime) if needed to achieve glycemic control. This is especially true when using
_______ which has a shorter duration than Lantus or Levemir - ANSWER ✓ NPH
Criteria for pre-DM or DM screening in asymptomatic adults - ANSWER ✓ BMI
> 25 or > 23/asian
1st degree relative w/ it
AA, Latino, Asian ethnicity
CVD history
>130/80 BP or on HTN meds
HDL <35, Trig >250
PCOS
Inactivity
, Difference between DM T1 & T2 - ANSWER ✓ 1 - beta cells destroyed, not able
to produce insulin/deficiency, develops in childhood, can go into DKA
2 - insulin resistance and inability of beta cells to secrete insulin, not enough
insulin or doesn't use it efficiently, can go into HHS
If pre-DM & a1c >5.7 - ANSWER ✓ test yearly
If GDM - ANSWER ✓ test for life every 3 years
tested @ 24-48 weeks gestation
For everyone else, test @ - ANSWER ✓ 35 yo every 3 yrs
Around onset of puberty/10 yo consider DM screening if - ANSWER ✓ BMI
>85%-95% and have RF:
maternal history or GDM
t2 fhx
ethnicity
signs of insulin resistance
*if normal, repeat in 1-3 yrs
a1c goal <7%
A1C recommendations - ANSWER ✓ Sickle cell, in 2nd or 3rd trimester, PP
period, G6PD, HIV, hemodialysis, recent blood loss or transfusion, erythropoietin
To diagnose DM, need: - ANSWER ✓ 2 abnormal test results from same sample
or 2 separate test samples
Pre DM #'s - ANSWER ✓ A1c 5.7-6.4
FBG 100-125
2 hr plasma glucose 140-199
DM #'s - ANSWER ✓ A1c >6.5%
FBG >126
2 hr plasma glucose >200
Meds that increase risk for DM - ANSWER ✓ glucocorticoids, thiazide diuretics,
some HIV meds, atypical antipsychotics
, Consider Metformin if pre DM &... - ANSWER ✓ BMI >35, <60 yo, female with
prior GDM
Metformin can be associated with B12 deficiency
Consider screening for __ w/ type 1 DM - ANSWER ✓ thyroid disease & celiac
Physical activity recommendations for children w/ pre DM and DM - ANSWER
✓ 60 min/day of moderate or vigorous aerobic activity, muscle strengthening 3
days/wk
A1c goal for non pregnant adults - ANSWER ✓ <7%
A1c goal for diabetic kids - ANSWER ✓ T1DM <7.5%
T2DM <7%
A1c goal if pregnant - ANSWER ✓ <6%
Level 1 Hypoglycemia - ANSWER ✓ <70, give 15-20g oral glucose/3-4gluc tab,
1serv gluc gel, 4oz juice, 4oz soft drink, 8oz milk, 5-6 hard candy, 1tb sugar/honey
Level 2 Hypoglycemia - ANSWER ✓ <54, give glucagon
T2 & obesity intervention - ANSWER ✓ >16 sessions in 6mo of high intensity
focus on diet, physical activity, behavioral strategies to achieve 500-750 kcal/day
energy deficit
Weight-loss medications can be an adjunct with __ patients - ANSWER ✓ T2
DM + BMI >27
<5% weight Loss after 3 mo on medications OR significant safety/tolerability
issues: d/c med & evaluate alternative medications/tx
Recommend metabolic sx for T2 DM if BMI... - ANSWER ✓ BMI >40
BMI >37.5 Asian