VME 7121: Exam 1 MOST RECENT EXAM ACTUAL COMPLETE REAL EXAM
QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS) ALREADY
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Which cells are derived from the myeloid lineage?
Neutrophils, eosinophils, basophils, mast cells, monocytes, and dendritic cells.
What types of cells arise from the lymphoid lineage?
B cells, T cells, and NK cells.
What is the primary function of neutrophils at infection sites?
To kill pathogens by phagocytosis and degranulation.
What is the characteristic feature of neutrophil nuclei?
They have a segmented (multi-lobed) nucleus.
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What role do eosinophils play in the immune system?
They are especially important in defense against helminth infections.
What do eosinophil granules trigger in mast cells and basophils?
Degranulation.
What do basophils release that is important in acute inflammation?
Vasoactive mediators.
Where do mast cells reside and what do they release during allergic
reactions?
Mast cells reside in tissues and release histamine and vasoactive mediators.
What do circulating monocytes differentiate into upon entering tissues?
Macrophages and dendritic cells.
How are macrophages named differently?
Depending on their tissue location (e.g., Kupffer cells in the liver, alveolar
macrophages in the lungs).
What are dendritic cells known for?
Being the most potent antigen-presenting cells.
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, 4/17/26, 10:43 PM VME 7121: Exam 1
What are the two types of T cells and their functions?
CD4 T cells are helper T cells, and CD8 T cells are cytotoxic T cells.
What can B cells become after activation?
Plasma cells that secrete antibodies or long-lived memory cells.
What is unique about NK cells in terms of specificity?
They can kill virus/bacteria-infected cells and tumor cells without antigen
specificity.
What is autocrine signaling?
A cell acts on itself.
What is paracrine signaling?
A cell acts on nearby cells.
What is endocrine signaling?
Mediators travel via the bloodstream to act on distant cells.
Where is the thymus located and what occurs there?
In the cranial mediastinum, where T cells undergo positive and negative
selection.
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