NURS 327 Complete Exam Prep
Pack – Study Guide +
Questions & Answers (2026)
1. Which condition requires contact precautions?
A. Measles
B. Varicella
C. Mumps
D. Clostridium difficile
Answer: Clostridium difficile
Rationale: C. difficile spreads via spores on surfaces
→ requires contact precautions + soap and water
(not alcohol san
itizer).
2. After exposure to a client with C. difficile, what
is the most appropriate hand hygiene method?
Answer: Wash hands with soap and water
Rationale: Alcohol-based sanitizers do not kill
spores.
,3. Which precaution is required for influenza?
Answer: Droplet precautions
Rationale: Influenza spreads via respiratory
droplets, not airborne.
4. Which disease requires airborne precautions?
Answer: Measles
Rationale: Measles spreads via airborne particles
that remain suspended.
5. What is the most effective way to prevent
hospital-acquired infections?
Answer: Hand hygiene
Rationale: The single most important infection
control measure.
Pain Management
6. Which substance decreases pain transmission?
A. Substance P
B. Acetylcholine
C. Endorphins
,D. Histamine
Answer: Endorphins
Rationale: Endorphins are natural opioids that
block pain signals.
7. Which neurotransmitter increases pain
transmission?
A. Endorphins
B. Substance P
C. Serotonin
D. Dopamine
Answer: Substance P
Rationale: Substance P carries pain signals to the
brain.
8. Which characteristic best describes acute pain?
Answer: It is specific and localized
Rationale: Acute pain is short-term and linked to
injury.
9. What is the priority assessment for a client on
PCA?
, Answer: Respiratory status
Rationale: Opioids can cause respiratory
depression, which is life-threatening.
10. Which statement about placebos is correct?
Answer: They should never be used to test if pain
is real
Rationale: Pain is subjective; placebo use is
unethical for testing honesty.
Sexually Transmitted Infections (STIs)
11. Which STI is not curable?
A. Chlamydia
B. Gonorrhea
C. Syphilis
D. Genital herpes
Answer: Genital herpes
Rationale: HSV remains latent for life; treatment
only suppresses symptoms.
Pack – Study Guide +
Questions & Answers (2026)
1. Which condition requires contact precautions?
A. Measles
B. Varicella
C. Mumps
D. Clostridium difficile
Answer: Clostridium difficile
Rationale: C. difficile spreads via spores on surfaces
→ requires contact precautions + soap and water
(not alcohol san
itizer).
2. After exposure to a client with C. difficile, what
is the most appropriate hand hygiene method?
Answer: Wash hands with soap and water
Rationale: Alcohol-based sanitizers do not kill
spores.
,3. Which precaution is required for influenza?
Answer: Droplet precautions
Rationale: Influenza spreads via respiratory
droplets, not airborne.
4. Which disease requires airborne precautions?
Answer: Measles
Rationale: Measles spreads via airborne particles
that remain suspended.
5. What is the most effective way to prevent
hospital-acquired infections?
Answer: Hand hygiene
Rationale: The single most important infection
control measure.
Pain Management
6. Which substance decreases pain transmission?
A. Substance P
B. Acetylcholine
C. Endorphins
,D. Histamine
Answer: Endorphins
Rationale: Endorphins are natural opioids that
block pain signals.
7. Which neurotransmitter increases pain
transmission?
A. Endorphins
B. Substance P
C. Serotonin
D. Dopamine
Answer: Substance P
Rationale: Substance P carries pain signals to the
brain.
8. Which characteristic best describes acute pain?
Answer: It is specific and localized
Rationale: Acute pain is short-term and linked to
injury.
9. What is the priority assessment for a client on
PCA?
, Answer: Respiratory status
Rationale: Opioids can cause respiratory
depression, which is life-threatening.
10. Which statement about placebos is correct?
Answer: They should never be used to test if pain
is real
Rationale: Pain is subjective; placebo use is
unethical for testing honesty.
Sexually Transmitted Infections (STIs)
11. Which STI is not curable?
A. Chlamydia
B. Gonorrhea
C. Syphilis
D. Genital herpes
Answer: Genital herpes
Rationale: HSV remains latent for life; treatment
only suppresses symptoms.
