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ATI PN PHARMACOLOGY PROCTORED EXAM
2026-2027 | 400+ PRACTICE QUESTIONS &
RATIONALES | HIGH-YIELD CONTENT | NGN-
STYLE | A+ STUDY GUIDE**
## Table of Contents
1. **Cardiovascular Medications** (Q1–Q50)
2. **Respiratory Medications** (Q51–Q75)
3. **Gastrointestinal Medications** (Q76–Q100)
4. **Endocrine Medications (Diabetes, Thyroid, Adrenal)** (Q101–
Q140)
5. **Neurological & Psychiatric Medications** (Q141–Q180)
6. **Pain Management & Opioids** (Q181–Q210)
7. **Antibiotics & Anti-infectives** (Q211–Q260)
8. **Anticoagulants & Hematologic Agents** (Q261–Q290)
9. **Renal & Fluid/Electrolyte Medications** (Q291–Q320)
10. **Immunizations, Antineoplastics & Miscellaneous** (Q321–Q350)
11. **Medication Administration & Safety** (Q351–Q380)
12. **High-Yield NGN Case Scenarios** (Q381–Q400)
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Section 1: Cardiovascular Medications (Q1–Q50)
**Q1.** A nurse is administering digoxin to a client with heart failure.
Which finding indicates possible digoxin toxicity?
A. Nausea, vomiting, yellow vision, and bradycardia
B. Increased appetite and tachycardia
C. Hypertension and hyperglycemia
D. Diarrhea and polyuria
**Correct Answer: A – Nausea, vomiting, yellow vision, bradycardia**
*Rationale: Digoxin toxicity presents with GI symptoms (nausea,
vomiting), visual disturbances (yellow-green halos), and bradycardia.*
**Q2.** A client is prescribed furosemide (Lasix) for heart failure.
Which electrolyte imbalance is the nurse most concerned about?
A. Hypokalemia
B. Hyperkalemia
C. Hyponatremia
D. Hypercalcemia
**Correct Answer: A – Hypokalemia**
*Rationale: Furosemide is a loop diuretic that causes potassium wasting;
hypokalemia increases risk of digoxin toxicity and arrhythmias.*
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**Q3.** A client taking lisinopril (ACE inhibitor) develops a persistent
dry cough. The nurse should:
A. Document as an expected side effect and continue the medication
B. Stop the medication immediately
C. Notify the provider; the medication may need to be changed
D. Administer an antitussive
**Correct Answer: C – Notify the provider; medication may need to be
changed**
*Rationale: Dry cough is a common side effect of ACE inhibitors;
switching to an ARB may be indicated.*
**Q4.** A client is prescribed warfarin (Coumadin). Which laboratory
test is used to monitor therapy?
A. INR (international normalized ratio)
B. aPTT
C. Platelet count
D. Bleeding time
**Correct Answer: A – INR**
*Rationale: Warfarin is monitored by INR; therapeutic INR is typically
2–3 for most indications.*
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**Q5.** A client on warfarin has an INR of 4.5 without bleeding. The
nurse should:
A. Hold the next dose and notify the provider
B. Administer vitamin K immediately
C. Continue the same dose
D. Increase the dose
**Correct Answer: A – Hold the next dose and notify the provider**
*Rationale: INR >4 but <5 without bleeding: hold dose or reduce dose;
vitamin K is for INR >10 or bleeding.*
**Q6.** A nurse is teaching a client about sublingual nitroglycerin.
Which instruction is correct?
A. “Place one tablet under your tongue at the first sign of chest pain.”
B. “Swallow the tablet with a full glass of water.”
C. “You may take up to 5 tablets in 10 minutes.”
D. “Store the tablets in a warm, moist place.”
**Correct Answer: A – Place one tablet under the tongue at first sign of
chest pain**
*Rationale: Sublingual nitroglycerin is absorbed through the oral
mucosa; take one, wait 5 minutes, then up to 3 doses total.*
ATI PN PHARMACOLOGY PROCTORED EXAM
2026-2027 | 400+ PRACTICE QUESTIONS &
RATIONALES | HIGH-YIELD CONTENT | NGN-
STYLE | A+ STUDY GUIDE**
## Table of Contents
1. **Cardiovascular Medications** (Q1–Q50)
2. **Respiratory Medications** (Q51–Q75)
3. **Gastrointestinal Medications** (Q76–Q100)
4. **Endocrine Medications (Diabetes, Thyroid, Adrenal)** (Q101–
Q140)
5. **Neurological & Psychiatric Medications** (Q141–Q180)
6. **Pain Management & Opioids** (Q181–Q210)
7. **Antibiotics & Anti-infectives** (Q211–Q260)
8. **Anticoagulants & Hematologic Agents** (Q261–Q290)
9. **Renal & Fluid/Electrolyte Medications** (Q291–Q320)
10. **Immunizations, Antineoplastics & Miscellaneous** (Q321–Q350)
11. **Medication Administration & Safety** (Q351–Q380)
12. **High-Yield NGN Case Scenarios** (Q381–Q400)
,2|Page
Section 1: Cardiovascular Medications (Q1–Q50)
**Q1.** A nurse is administering digoxin to a client with heart failure.
Which finding indicates possible digoxin toxicity?
A. Nausea, vomiting, yellow vision, and bradycardia
B. Increased appetite and tachycardia
C. Hypertension and hyperglycemia
D. Diarrhea and polyuria
**Correct Answer: A – Nausea, vomiting, yellow vision, bradycardia**
*Rationale: Digoxin toxicity presents with GI symptoms (nausea,
vomiting), visual disturbances (yellow-green halos), and bradycardia.*
**Q2.** A client is prescribed furosemide (Lasix) for heart failure.
Which electrolyte imbalance is the nurse most concerned about?
A. Hypokalemia
B. Hyperkalemia
C. Hyponatremia
D. Hypercalcemia
**Correct Answer: A – Hypokalemia**
*Rationale: Furosemide is a loop diuretic that causes potassium wasting;
hypokalemia increases risk of digoxin toxicity and arrhythmias.*
,3|Page
**Q3.** A client taking lisinopril (ACE inhibitor) develops a persistent
dry cough. The nurse should:
A. Document as an expected side effect and continue the medication
B. Stop the medication immediately
C. Notify the provider; the medication may need to be changed
D. Administer an antitussive
**Correct Answer: C – Notify the provider; medication may need to be
changed**
*Rationale: Dry cough is a common side effect of ACE inhibitors;
switching to an ARB may be indicated.*
**Q4.** A client is prescribed warfarin (Coumadin). Which laboratory
test is used to monitor therapy?
A. INR (international normalized ratio)
B. aPTT
C. Platelet count
D. Bleeding time
**Correct Answer: A – INR**
*Rationale: Warfarin is monitored by INR; therapeutic INR is typically
2–3 for most indications.*
, 4|Page
**Q5.** A client on warfarin has an INR of 4.5 without bleeding. The
nurse should:
A. Hold the next dose and notify the provider
B. Administer vitamin K immediately
C. Continue the same dose
D. Increase the dose
**Correct Answer: A – Hold the next dose and notify the provider**
*Rationale: INR >4 but <5 without bleeding: hold dose or reduce dose;
vitamin K is for INR >10 or bleeding.*
**Q6.** A nurse is teaching a client about sublingual nitroglycerin.
Which instruction is correct?
A. “Place one tablet under your tongue at the first sign of chest pain.”
B. “Swallow the tablet with a full glass of water.”
C. “You may take up to 5 tablets in 10 minutes.”
D. “Store the tablets in a warm, moist place.”
**Correct Answer: A – Place one tablet under the tongue at first sign of
chest pain**
*Rationale: Sublingual nitroglycerin is absorbed through the oral
mucosa; take one, wait 5 minutes, then up to 3 doses total.*
