1|Page
NR 667 AANP FNP EXAM 2 TEST BANK 2026/2027
– 210 UNIQUE NCLEX-STYLE QUESTIONS WITH
DETAILED RATIONALES, HIGH-YIELD
CONTENT, GRADED A+, FIRST-TIME PASS
GUARANTEED
TABLE OF CONTENTS
| Section | Title | Page |
| **Domain 1** | Health Promotion & Disease Prevention (Questions 1-
35) |
| **Domain 2** | Cardiovascular & Hematologic Disorders (Questions
36-70) |
| **Domain 3** | Pulmonary & ENT Disorders (Questions 71-105) |
| **Domain 4** | Endocrine & Metabolic Disorders (Questions 106-140)
| **Domain 5** | Neurologic & Musculoskeletal Disorders (Questions
141-175)
| **Domain 6** | Gastrointestinal & Renal/Genitourinary (Questions
176-210)
,2|Page
DOMAIN 1: HEALTH PROMOTION & DISEASE PREVENTION
(Questions 1-35)
**1.** A 55-year-old asymptomatic male with a 30-pack-year smoking
history presents for a wellness visit. According to USPSTF guidelines,
which screening is most appropriate?
A) Annual chest X-ray
B) Low-dose CT chest annually
C) Sputum cytology every 2 years
D) No screening indicated
**Answer: B**
*Rationale:* USPSTF recommends annual low-dose CT screening for
lung cancer in adults aged 50-80 with ≥20 pack-year history who
currently smoke or quit within 15 years.
*High Yield:* Shared decision-making required before screening.
**2.** A 68-year-old female has a bone density T-score of -2.8 at the
femoral neck. What is the most appropriate initial pharmacologic
therapy?
A) Calcium and vitamin D only
B) Alendronate (bisphosphonate)
C) Raloxifene
D) Teriparatide
,3|Page
**Answer: B**
*Rationale:* T-score ≤ -2.5 = osteoporosis. First-line = bisphosphonates
(alendronate, risedronate) to reduce fracture risk. Calcium/vitamin D are
adjunctive.
*High Yield:* FRAX tool assesses 10-year fracture risk.
**3.** A 45-year-old female asks about breast cancer screening. She has
no family history. What does USPSTF recommend?
A) Mammography annually starting at age 40
B) Mammography every 2 years starting at age 50
C) Mammography every 2 years ages 50-74
D) No screening until age 50
**Answer: C**
*Rationale:* USPSTF recommends biennial mammography for women
ages 50-74 (Grade B). For ages 40-49, individual decision (Grade C).
*High Yield:* ACOG recommends annual starting at age 40.
**4.** A 30-year-old sexually active female requests cervical cancer
screening. She has never had an abnormal Pap. What is recommended?
A) Pap every year
B) Pap every 3 years (age 21-29)
, 4|Page
C) Pap + HPV co-testing every 5 years (age 30-65)
D) HPV testing alone every 5 years
**Answer: B**
*Rationale:* Age 21-29: Pap alone every 3 years. Age 30-65: Pap +
HPV co-testing every 5 years OR Pap alone every 3 years.
*High Yield:* Stop screening after age 65 if adequate prior negative
screens.
**5.** A 72-year-old male with hypertension asks about colorectal
cancer screening. He has no symptoms and a negative colonoscopy at
age 65. What do you advise?
A) Repeat colonoscopy now
B) No further screening needed
C) Annual FIT testing
D) Repeat colonoscopy in 10 years
**Answer: B**
*Rationale:* USPSTF recommends screening ages 45-75. After age 75,
individualized decision. With negative colonoscopy at 65, no further
screening is reasonable.
*High Yield:* Screening generally stops at age 85.
NR 667 AANP FNP EXAM 2 TEST BANK 2026/2027
– 210 UNIQUE NCLEX-STYLE QUESTIONS WITH
DETAILED RATIONALES, HIGH-YIELD
CONTENT, GRADED A+, FIRST-TIME PASS
GUARANTEED
TABLE OF CONTENTS
| Section | Title | Page |
| **Domain 1** | Health Promotion & Disease Prevention (Questions 1-
35) |
| **Domain 2** | Cardiovascular & Hematologic Disorders (Questions
36-70) |
| **Domain 3** | Pulmonary & ENT Disorders (Questions 71-105) |
| **Domain 4** | Endocrine & Metabolic Disorders (Questions 106-140)
| **Domain 5** | Neurologic & Musculoskeletal Disorders (Questions
141-175)
| **Domain 6** | Gastrointestinal & Renal/Genitourinary (Questions
176-210)
,2|Page
DOMAIN 1: HEALTH PROMOTION & DISEASE PREVENTION
(Questions 1-35)
**1.** A 55-year-old asymptomatic male with a 30-pack-year smoking
history presents for a wellness visit. According to USPSTF guidelines,
which screening is most appropriate?
A) Annual chest X-ray
B) Low-dose CT chest annually
C) Sputum cytology every 2 years
D) No screening indicated
**Answer: B**
*Rationale:* USPSTF recommends annual low-dose CT screening for
lung cancer in adults aged 50-80 with ≥20 pack-year history who
currently smoke or quit within 15 years.
*High Yield:* Shared decision-making required before screening.
**2.** A 68-year-old female has a bone density T-score of -2.8 at the
femoral neck. What is the most appropriate initial pharmacologic
therapy?
A) Calcium and vitamin D only
B) Alendronate (bisphosphonate)
C) Raloxifene
D) Teriparatide
,3|Page
**Answer: B**
*Rationale:* T-score ≤ -2.5 = osteoporosis. First-line = bisphosphonates
(alendronate, risedronate) to reduce fracture risk. Calcium/vitamin D are
adjunctive.
*High Yield:* FRAX tool assesses 10-year fracture risk.
**3.** A 45-year-old female asks about breast cancer screening. She has
no family history. What does USPSTF recommend?
A) Mammography annually starting at age 40
B) Mammography every 2 years starting at age 50
C) Mammography every 2 years ages 50-74
D) No screening until age 50
**Answer: C**
*Rationale:* USPSTF recommends biennial mammography for women
ages 50-74 (Grade B). For ages 40-49, individual decision (Grade C).
*High Yield:* ACOG recommends annual starting at age 40.
**4.** A 30-year-old sexually active female requests cervical cancer
screening. She has never had an abnormal Pap. What is recommended?
A) Pap every year
B) Pap every 3 years (age 21-29)
, 4|Page
C) Pap + HPV co-testing every 5 years (age 30-65)
D) HPV testing alone every 5 years
**Answer: B**
*Rationale:* Age 21-29: Pap alone every 3 years. Age 30-65: Pap +
HPV co-testing every 5 years OR Pap alone every 3 years.
*High Yield:* Stop screening after age 65 if adequate prior negative
screens.
**5.** A 72-year-old male with hypertension asks about colorectal
cancer screening. He has no symptoms and a negative colonoscopy at
age 65. What do you advise?
A) Repeat colonoscopy now
B) No further screening needed
C) Annual FIT testing
D) Repeat colonoscopy in 10 years
**Answer: B**
*Rationale:* USPSTF recommends screening ages 45-75. After age 75,
individualized decision. With negative colonoscopy at 65, no further
screening is reasonable.
*High Yield:* Screening generally stops at age 85.
