cytoprotectant drugs - CORRECT ANSWER-reduce the adverse effects of cytotoxic
drugs, some of which can be severe, debilitating or life-threatening
loop diuretics - CORRECT ANSWER-diuretic of choice when rapid effects are required,
i.e. pulmonary edema or renal impairment
spironolactone - CORRECT ANSWER-K+-sparing, diureticreduces aldosterone-induced
retention of sodium and water and impairs vascular function by antagonizing the action
of aldosterone at mineralocorticoid receptors
reduced sodium - CORRECT ANSWER-diet modification that helps diuretic drugs be
more effective
hypokalemia - CORRECT ANSWER-can result from hydrochlorothiazide, lasix; may be
prescribed a supplement by provider to prevent
hyperkalemia - CORRECT ANSWER-not usually caused by K+-sparing diuretics,
overuse of supplements or salt substitute use; most likely to occur in patients with
impaired renal function and diabetes
potassium imbalances - CORRECT ANSWER-diuretics may cause this condition that
may damage heart function
reactions produced by SNS - CORRECT ANSWER--increased blood pressure/cardiac
output
-increased rate of cellular metabolism
-increased blood glucose
-increased mental activity
-increased rate of blood coagulation
-increased rate/ depth of respiration
-pupil dilation to aid vision
-increased sweating
acetaminophen - CORRECT ANSWER-produces analgesic effect and reduces fever but
does not reduce inflammation
corticosteroids - CORRECT ANSWER-needs to be tapered, current or previous therapy
can influence treatment measures
, gentamicin - CORRECT ANSWER-accumulates in the inner ear causing disrupted
balance or hearing
goals of treatment in hyperthyroidism - CORRECT ANSWER--reduce thyroid hormone
production
-return serum TSH and thyroid hormone levels to normal
-avoid complete destruction of thyroid
seafood and iodized salt - CORRECT ANSWER-when taking propylthiouracil, the doctor
may restrict this
propanol - CORRECT ANSWER-in hyperthyroidism, blocks beta-adrenergic receptors
in various organs and thereby controls symptoms of hyperthyroidism resulting in
excessive stimulation from the sympathetic nervous system
propylthiouracil route and dosage range (adult) - CORRECT ANSWER-300-400 mg/d
PO in divided doses q8h then 100-150 mg/d in divided dose q8h
liver damage - CORRECT ANSWER-BBW for propythiouracil, required hepatic fn test
cretinism - CORRECT ANSWER-congenital hypothyroidism
myxedema - CORRECT ANSWER-hypothyroidism after early childhood
CNS depressants - CORRECT ANSWER-a person with severe hypothyroidism cannot
metabolize and excrete these, necessary to assess the patient for signs of adverse drug
activity
synthroid - CORRECT ANSWER-therapeutic effects include increased energy,
diminished sleep, increased level of alertness and interest in surroundings
assessing adverse effects of synthroid - CORRECT ANSWER-chest pain, edema, and
signs of heart failure
patient teaching for levothyroxine - CORRECT ANSWER-take drug every morning on
an empty stomach; avoid taking drug with antacids, iron preparations or sucralfate
LH-releasing hormone agonist (leuprolide) - CORRECT ANSWER-act as potent
inhibitors of gonadotropin secretions, thus suppressing production of ovarian and
testicular steroids; useful in treatment of central precocious puberty in child
BBW for desmopressin acetate - CORRECT ANSWER-severe hyponatremia may
develop, could lead to seizures and death
therapeutic effects of hydrocortisone - CORRECT ANSWER--assess blood pressure,
pulse and respirations for improved cardiac function