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12 TO 14 YEARS (EARLY ADOLESCENCE)(STAGES OF DEVELOPMENT IN SULLIVAN'S INTERPERSONAL
THEORY) - CORRECT ANSWER ✔✔✔ Learning to form satisfactory relationships with persons of the
opposite sex; developing a sense of identity

Neuroanatomy - CORRECT ANSWER ✔✔✔ ***Neuroanatomy

60 y/o right-handed M, getting lost, only writes on right half of paper. Left-sided hemi-neglect. Where is
the lesion? (8x)

*(w)Rights Partial= R Parietal - CORRECT ANSWER ✔✔✔ RIGHT PARIETAL LOBE

66 y/o with HTN develops vertigo, diplopia, nausea, vomiting, hiccups, L face numbness, nystagmus,
hoarseness, ataxia of limbs, staggering gait, and tendency to fall to the left. Dx? (8x)

*Le MI PICcup Miself, Eye am Tipsi and my other side is numb - CORRECT ANSWER ✔✔✔ LATERAL
MEDULLARY STROKE

"78 y/o pt had an ischemic stroke that left him with a residual mild hemiplegia. Pt appeared to be
unaware that there was a problem of weakness on one side of this body. When asked to raise the weak
arm, the patient raised his normal arm. When the failure to raise the paralyzed arm was pointed out to
pt, he admitted that the arm was slightly weak. He also neglects the side of the body when dressing and
grooming. Pt did not shave one side of his face, had difficulty putting a shirt on when it was turned
inside out. Area of brain likely affected by stroke? (4x)" - CORRECT ANSWER ✔✔✔ RIGHT PARIETAL
LOBE

26 y.o. w/HA and R-hand clumsiness for weeks. Exam shows difficulty w/ rapid alternating movements
of hand, overt intention tremor on finger-to- nose, and mildly dysmetric finger tamping. CNS intact and
no papilledema. Where will damage show on MRI? (4x) - CORRECT ANSWER ✔✔✔ CEREBELLUM

Adult neurogenesis in which area of the brain? (x2) - CORRECT ANSWER ✔✔✔ HIPPOCAMPUS

Previously pleasant mom becomes profane and irresponsible over 6 months. Most likely a pathology in:
(2x) - CORRECT ANSWER ✔✔✔ FRONTAL LOBE

Rapid onset of right facial weakness, left limb weakness, diplopia: (2x) - CORRECT ANSWER ✔✔✔
BRAIN STEM INFARCTION

MRI scan of head reveals an infarct in distribution of left anterior cerebral artery. Pt most likely exhibits:
(2x) - CORRECT ANSWER ✔✔✔ WEAKNESS OF CONTRALATERAL FOOT AND LEG

Neurogenesis in adult brain is restricted to what region of brain? - CORRECT ANSWER ✔✔✔ DENTATE
GYRUS (gyrus-generates dentrites/neurons)

bipolar has decreased connectivity here - CORRECT ANSWER ✔✔✔ AMYGDALA AND PFC

Biogenic amine made in Locus Coeruleus - CORRECT ANSWER ✔✔✔ NE

,CNS response to fear mediated by what structure. - CORRECT ANSWER ✔✔✔ CENTRAL NUCLEUS OF
THE AMYGDALA

Brain area activated by subliminal presentations of emotional faces - CORRECT ANSWER ✔✔✔
AMYGDALA

CNS region from where dopaminergic neurons projecting to caudate and putamen - CORRECT ANSWER
✔✔✔ SUBSTANTIA NIGRA

Area of brain responsible for face recognition - CORRECT ANSWER ✔✔✔ FUSIFORM GYRUS

area of brain to remember a number to make a phone call - CORRECT ANSWER ✔✔✔ DORSOLATERAL
PFC

Which part of cortical-striatal-pallidal-thalamic cortical circuit evaluates painful stimuli - CORRECT
ANSWER ✔✔✔ LATERAL ORBITOFRONTAL

The dorsolateral-prefrontal cortex, striatum and are part of a loop circuit that produces worry and
obsessive symptoms - CORRECT ANSWER ✔✔✔ THALAMUS

blood-brain barrier is made up of this cell type? - CORRECT ANSWER ✔✔✔ ENDOTHELIAL

Orexin is made in what part of the brain? - CORRECT ANSWER ✔✔✔ HYPOTHALAMUS

So dopamine neurons in what system is primarily implicated in tasks related to cognitive processing? -
CORRECT ANSWER ✔✔✔ MESOCORTICAL "DA makes Me So Cognitive"

Which dopaminergic pathway includes the nucleus accumbens and mediates addiction and associated
behaviors? - CORRECT ANSWER ✔✔✔ MESOLIMBIC

Development of brain grey-matter volume peaks at what stage - CORRECT ANSWER ✔✔✔ LATE
CHILDHOOD

In a pt with hippocampus damage, what allows them to still learn new skills like playing tennis? -
CORRECT ANSWER ✔✔✔ BASAL GANGLIA

65 y/o pt has a stroke which causes him to fall. On exam, weakness of the right leg, with only minor
weakness of the right hand, no weakness of the face, no sensory deficit. Speech is not affected, but pt
seems unusually quiet and passive. The stroke most likely involves the: - CORRECT ANSWER ✔✔✔ LEFT
ANTERIOR CEREBRAL ARTERY

Hemisensory loss followed by pain and hyperpathia involving all modalities and reaching the midline of
trunk and head is most consistent with ischemia in the distribution of which of the following arteries? -
CORRECT ANSWER ✔✔✔ POSTERIOR CEREBRAL

Right-side palsy with equal involvement of the face, arm and leg combined with third nerve palsy is most
likely due to occlusion of a branch of which artery? - CORRECT ANSWER ✔✔✔ POSTERIOR CEREBRAL

Bilateral lower extremity weakness, abulia, mutism, urinary incontinence are most likely to result from
occlusion of which of the following arteries? - CORRECT ANSWER ✔✔✔ ANTERIOR CEREBRAL Artery

,Pure sensory deficit extending to midline and involving face, arm, trunk, and leg caused by lacunar
infarct where? - CORRECT ANSWER ✔✔✔ LATERAL THALAMUS

Blocking R PCA (posterior cerebral artery) causes which visual disturbance? - CORRECT ANSWER ✔✔✔
LEFT HOMONYMOUS HEMIANOPSIA

The clinical syndrome associated with occlusion of the cortical branch of the posterior cerebral artery
would result in which of the following? - CORRECT ANSWER ✔✔✔ HOMONYMOUS HEMIANOPIA WITH
ALEXIA WITHOUT AGRAPHIA (when extended to splenium of corpus callosum)

28 y/o cocaine user complains of LBP, numbness in both legs and feet, thighs, buttocks, abdomen, and
says R leg is weak and clumsy, L leg is tired. Has urinary incontinence and difficulty walking. Decreased
light touch, pinprick, and temperature. Normal vibration and proprioception. DTR is hard to elicit.
Muscle tone is normal. Decreased strength in B/L LE but worse on right. Diagnosis? - CORRECT ANSWER
✔✔✔ ANTERIOR SPINAL ARTERY INFARCTION

Loss of ability to execute previously learned motor activities (which is not the result of demonstrable
weakness, ataxia or sensory loss) is associated with lesions of? - CORRECT ANSWER ✔✔✔ LEFT
PARIETAL CORTEX

Normal Romberg w/ eyes open but loses balance with eyes closed. Where is the abnormality? -
CORRECT ANSWER ✔✔✔ CEREBELLAR VERMIS

Motor speech paradigm activation task on fMRI - hyperactivity in right temporal lobe. Damage is where?
- CORRECT ANSWER ✔✔✔ CALCARINE FISSURE

Aphasia w/ effortful fragmented, non-fluent, telegraphic speech, is seen in a lesion where? - CORRECT
ANSWER ✔✔✔ POSTERIOR FRONTAL LOBE

A pituitary tumor that protrudes through the diaphragmatic sella is most likely to cause? - CORRECT
ANSWER ✔✔✔ BITEMPORAL HEMIANOPSIA

Conduction aphasia often occurs as a result of damage to which structure? - CORRECT ANSWER ✔✔✔
ARCUATE FASCICULUS: (can't repeat phrases)

Unilateral hearing loss, vertigo, unsteadiness, falls, headaches, mild facial weakness and ipsilateral limb
ataxia is most commonly associated with tumors in what locations? - CORRECT ANSWER ✔✔✔
CEREBELLOPONTINE ANGLE

20 y/o with 1-year h/o bitemporal headaches, polydipsia, polyuria, and bulimia plus 2-month h/o
emotional outbursts, aggression, and transient confusion. Neuro exam normal. What will MRI of brain
show? - CORRECT ANSWER ✔✔✔ HYPOTHALAMIC TUMOR

"34 y/o M is referred for psychiatric evaluation 5 years after sustaining a head injury at work. Prior to
the accident, he was a stable, happily married man. Since the accident, he has been described as overly
talkative and restless. His wife divorced him because he was acting irresponsibly, which also resulted in
termination from his job. Psychometric testing reveals that the man has average intelligence and no
detectable memory deficits. Pt's clinical presentation is most consistent with damage to which to the
following brain areas?" - CORRECT ANSWER ✔✔✔ FRONTAL LOBE

, Pt reports headaches and peripheral visual loss. Visual field defects involving the temporal fields of both
eyes are detected. An MRI scan is likely to reveal? - CORRECT ANSWER ✔✔✔ A MASS IN THE SELLA
TURCICA

Unconsciousness can be induced by a small area of damage where? - CORRECT ANSWER ✔✔✔
RETICULAR FORMATION

Acute onset of hemiballismus of LUE & LLE. MRI is most likely to show lesion located where? - CORRECT
ANSWER ✔✔✔ SUBTHALAMIC NUCLEUS

Akinetic mutism can result from bilateral infarctions of which of the following structures: - CORRECT
ANSWER ✔✔✔ ANTERIOR CINGULATE GYRUS

"Which lesion causes bilateral coarse nystagmus worsening with visual fixation and present with
horizontal and vertical gaze?" - CORRECT ANSWER ✔✔✔ BRAINSTEM (vestibular nuclei: nystagmus)

32 y/o pt 1-month hx of worsening headaches, episodic mood swings and occasional hallucinations with
visual, tactile and auditory content. CT head reveals tumor where: - CORRECT ANSWER ✔✔✔
TEMPORAL LOBE

What does the cerebellum do in the human adult brain? - CORRECT ANSWER ✔✔✔ DIVERSE ROLES IN
MOVEMENT, BEHAVIOR, AND LEARNING (CereBeLluM= Coordinate Behavior Learning & Movement)

Syndrome characterized by fluent speech, preserved comprehension, inability to repeat, w/o associated
signs. Location of lesion in the brain? - CORRECT ANSWER ✔✔✔ SUPRAMARGINAL GYRUS OR INSULA

Lesions in mammalary bodies will produce what symptom? - CORRECT ANSWER ✔✔✔ AMNESIA,
CONFABULATION, LACK OF INSIGHT

62yo progressive personality changes, has dull emotions, lack of initiative, and apathy. An autopsy is
likely to show atrophy of ...? - CORRECT ANSWER ✔✔✔ FRONTAL LOBE

Implantation of deep brain stimulation electrodes is an effective tx for Parkinson's. Optimal location for
electrodes? - CORRECT ANSWER ✔✔✔ SUBTHALAMIC NUCLEUS

Deep brain stimulation in which brain structure is a useful treatment for primary generalized dystonia? -
CORRECT ANSWER ✔✔✔ GLOBUS PALLIDUS

Mesolimbic DA pathway includes which structure? - CORRECT ANSWER ✔✔✔ VENTRAL STRIATUM

In addiction, dopaminergic neurons project to nucleus accumbens. Cell bodies of these neurons reside in
which area of brain? - CORRECT ANSWER ✔✔✔ VENTRAL TEGMENTAL AREA

Neural plasticity largely mediated through the capacity to rapidly change in number and morphology
which fo the following? - CORRECT ANSWER ✔✔✔ DENDRITIC SPINES

The uncinated fasciculus connects which of the following brain areas? - CORRECT ANSWER ✔✔✔
"ANTERIOR TEMPORAL AND VENTRAL PRE- FRONTAL Lobe REGIONS"

What are the cortical columns? - CORRECT ANSWER ✔✔✔ FUNCTIONAL UNITS FOR INFORMATION
PROCESSING

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