UNIT 3
BIOLOGY 1O 1
, Trates
science .
reacean
√
T
HERMODYNAMICS + KINETICS -
LECTURE 3A verganic enderganis
needed
spontaneous merg
^
Tot o
^
thurmadynamics , (ex
=>
the direction chemical reaction OGLO
cancer
proceeds spontaneous
:
a
deached
.
,
but ,
NOT the
speed the reactions
proceeds *
·
G50-enegyrequired) ~
↳
Lindenberg explosion german ship
(20
century) Cyagen agen-water
: FAST REACTION
&
+
BOTH SPONTANEOUS
↳ rust (slaw ractions unless to maisture)
irautenggen
=
,
exposed neededs
sen
engame
· clumical reactions must always proceed through an Carrier
~ange
energy
Marie
^
↳
system must achieve higher mergy state to complete
简武리 '
↳
ex
spark needed to ignite spantaneaus eplasion
.
gruric spontaneaus reaction ractants praducts
-
: > OG < C
reactants
hall
passes through through higher eergy
transition state
Stumporary in process of breaking-bending/stitching
·
pass
tanes
a
achie
to during state often readants
hand is strutted
·
_
a
ey , bent (BROKEN BOND
a
H) ar = -
*
reactions slawed
being trapped in metastable state
_
by
·
G &
difference in energy between reactants products
·
+
Ea -G unulated + >
Ea delemmes how reaction
fast (even when
_
Spontanans) accus
·
·
products are mast stable
·
reactants are mitastable >
partly/tmpararily
~
HETASTABILITY YOkg
ATP
eaily life metastable + its
clumistry is
↓
↑ is
a
huelysbeing
↳ cawbeatlireh
life is metastable ; the
equilibrium state
of s
human/Undenburg =
ASHES
fiitically by enzymes
↳ ~
crample : ☆ chemical reaction that accus
peptic every
Sfaveable)
hand is unstable (mater breaks hands <DG -Skcal/mol
·
peptide =
in
bolagy needs to havs D G10 + needs
half-time far reaction 7
large
to be
catalyzed by
·
Ea
:
years s an
eyye
slaw under the meld conditions
* all reactions a re
of life
= we
provide vatalysts that speed up just the beneficial reactions (LOWERS Ea-
different reaction path)
Lind to molecules
>
-
enzymes specific
:
sped up ther reaction wo/ each other +
thousands
↳ each
myyma catalyzes just I specific radiois alls have
ofsymes
↳ be turned an/
can
off ~
independently controlled rate
Thumadynaniscentral if reaction w/
hydrolysis
* : OG>0 is needed , it to
enzyme couples ATP
knitic contral: slaw reaction must speed
*
if accor
quickly ,
eyyme
used to
it
up .
fres energy
-
more is released the
further a reaction is
from equilibrim
-
lawce Carrier but impact
enzymes energy
do NOT
equllum
-
rates concentration increases until saturation
mygmatic increase as
、
BIOLOGY 1O 1
, Trates
science .
reacean
√
T
HERMODYNAMICS + KINETICS -
LECTURE 3A verganic enderganis
needed
spontaneous merg
^
Tot o
^
thurmadynamics , (ex
=>
the direction chemical reaction OGLO
cancer
proceeds spontaneous
:
a
deached
.
,
but ,
NOT the
speed the reactions
proceeds *
·
G50-enegyrequired) ~
↳
Lindenberg explosion german ship
(20
century) Cyagen agen-water
: FAST REACTION
&
+
BOTH SPONTANEOUS
↳ rust (slaw ractions unless to maisture)
irautenggen
=
,
exposed neededs
sen
engame
· clumical reactions must always proceed through an Carrier
~ange
energy
Marie
^
↳
system must achieve higher mergy state to complete
简武리 '
↳
ex
spark needed to ignite spantaneaus eplasion
.
gruric spontaneaus reaction ractants praducts
-
: > OG < C
reactants
hall
passes through through higher eergy
transition state
Stumporary in process of breaking-bending/stitching
·
pass
tanes
a
achie
to during state often readants
hand is strutted
·
_
a
ey , bent (BROKEN BOND
a
H) ar = -
*
reactions slawed
being trapped in metastable state
_
by
·
G &
difference in energy between reactants products
·
+
Ea -G unulated + >
Ea delemmes how reaction
fast (even when
_
Spontanans) accus
·
·
products are mast stable
·
reactants are mitastable >
partly/tmpararily
~
HETASTABILITY YOkg
ATP
eaily life metastable + its
clumistry is
↓
↑ is
a
huelysbeing
↳ cawbeatlireh
life is metastable ; the
equilibrium state
of s
human/Undenburg =
ASHES
fiitically by enzymes
↳ ~
crample : ☆ chemical reaction that accus
peptic every
Sfaveable)
hand is unstable (mater breaks hands <DG -Skcal/mol
·
peptide =
in
bolagy needs to havs D G10 + needs
half-time far reaction 7
large
to be
catalyzed by
·
Ea
:
years s an
eyye
slaw under the meld conditions
* all reactions a re
of life
= we
provide vatalysts that speed up just the beneficial reactions (LOWERS Ea-
different reaction path)
Lind to molecules
>
-
enzymes specific
:
sped up ther reaction wo/ each other +
thousands
↳ each
myyma catalyzes just I specific radiois alls have
ofsymes
↳ be turned an/
can
off ~
independently controlled rate
Thumadynaniscentral if reaction w/
hydrolysis
* : OG>0 is needed , it to
enzyme couples ATP
knitic contral: slaw reaction must speed
*
if accor
quickly ,
eyyme
used to
it
up .
fres energy
-
more is released the
further a reaction is
from equilibrim
-
lawce Carrier but impact
enzymes energy
do NOT
equllum
-
rates concentration increases until saturation
mygmatic increase as
、
