NSG 5140 Advanced Pathophysiology
Comprehensive Resource To Help You Ace 2026-2027 Exams
Includes Frequently Tested Questions With ELABORATED
100% Correct COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!! Current Update
1. Activation of the extrinsic pathway of coagulation is initiated by...
A) platelet factors
B) collagen exposure
C) tissue thromboplastin
D) factor VII - Correct Answer: tissue thromboplastin
2. The prothrombin time (PT) and INR (International Normalized Ratio)
measure the integrity of...
A) platelet function
B) extrinsic pathway
C) intrinsic pathway
D) fibrinolysis - Correct Answer: extrinsic pathway
3. The activated partial thromboplastin time (aPTT) is a measure of the
integrity of...
A) the extrinsic pathway
B) the intrinsic pathway
C) factor VIII synthesis
D) plasminogen - Correct Answer: intrinsic pathway
,4. A commonly ingested substance associated with prolongation of the
bleeding time is...
A) acetaminophen
B) tobacco
C) caffeine
D) aspirin - Correct Answer: aspirin
5. The megakaryocyte is a precursor to...
A) factor IX
B) white blood cells
C) red blood cells
D) platelets - Correct Answer: platelets
6. A cause of thrombocytopenia includes...
A) hypoxemia
B) reduced erythropoietin
C) chemotherapy
D) secondary polycythemia - Correct Answer: chemotherapy
7. widespread activation of the clotting cascade secondary to massive trauma
is called...
A) hemophilia B
B) disseminated intravascular coagulation (DIC)
C) Hageman disease
D) idiopathic thrombocytopenia purpura - Correct Answer:
disseminated intravascular coagulation (DIC)
8. A 3 year old boy who exhibits prolonged bleeding after minor trauma and a
prolonged aPTT, but a normal platelet count is likely to be diagnosed with...
, A) hemophilia
B) liver dysfunction
C) disseminated intravascular coagulation
D) thrombocytopenia - Correct Answer: hemophilia
9. Treatment for Hemophilia A includes...
A) heparin administration
B) factor IX replacement
C) factor VIII replacement
D) platelet transfusion - Correct Answer: Factor VIII replacement
10.Disseminated intravascular coagulation may be treated with heparin
therapy to...
A) enhance fibrinolysis
B) inhibit clotting factor consumption
C) activate platelets
D) enhance liver synthesis of clotting factors - Correct Answer:
inhibit clotting factor consumption
11.A deficiency of von Willebrand factor impairs...
A) activation of the coagulation cascade
B) platelet aggregation
C) platelet adhesion to injured tissue
D) platelet production - Correct Answer: platelet adhesion to injured
tissue
12.A patient is diagnosed with a tortuous blood vessel of the right hand that
bleeds spontaneously. This patient presents with...
A) petechiae
, B) purpura
C) telangiectasia
D) thrombocytosis - Correct Answer: Telangiectasia
13.A newborn has melena, bleeding from the umbilicus, and hematuria. The
newborn is most likely experiencing...
A) vitamin K deficiency bleeding
B) squired vitamin K deficiency
C) von Willebrand disease
D) disseminated intravascular coagulation - Correct Answer: Vitamin
K deficiency bleeding
14.What is involved in the release of plasminogen activators?
A) Factor X
B) Factor XII
C) HMWK
D) Kallikrein
E) Thrombin - Correct Answer: Factor XII
HMWK
Kallikrein
Thrombin
15.Which involves bleeding associated with vascular or platelet defects?
A) Bleeding that occurs immediately after trauma
B) Bleeding that involves skin or mucous membranes
C) Bleeding that is brief in duration
D) Bleeding that is delayed
E) Bleeding into muscles or joints - Correct Answer: Bleeding that
occurs immediately after trauma
Bleeding that involves skin or mucus membranes
Comprehensive Resource To Help You Ace 2026-2027 Exams
Includes Frequently Tested Questions With ELABORATED
100% Correct COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!! Current Update
1. Activation of the extrinsic pathway of coagulation is initiated by...
A) platelet factors
B) collagen exposure
C) tissue thromboplastin
D) factor VII - Correct Answer: tissue thromboplastin
2. The prothrombin time (PT) and INR (International Normalized Ratio)
measure the integrity of...
A) platelet function
B) extrinsic pathway
C) intrinsic pathway
D) fibrinolysis - Correct Answer: extrinsic pathway
3. The activated partial thromboplastin time (aPTT) is a measure of the
integrity of...
A) the extrinsic pathway
B) the intrinsic pathway
C) factor VIII synthesis
D) plasminogen - Correct Answer: intrinsic pathway
,4. A commonly ingested substance associated with prolongation of the
bleeding time is...
A) acetaminophen
B) tobacco
C) caffeine
D) aspirin - Correct Answer: aspirin
5. The megakaryocyte is a precursor to...
A) factor IX
B) white blood cells
C) red blood cells
D) platelets - Correct Answer: platelets
6. A cause of thrombocytopenia includes...
A) hypoxemia
B) reduced erythropoietin
C) chemotherapy
D) secondary polycythemia - Correct Answer: chemotherapy
7. widespread activation of the clotting cascade secondary to massive trauma
is called...
A) hemophilia B
B) disseminated intravascular coagulation (DIC)
C) Hageman disease
D) idiopathic thrombocytopenia purpura - Correct Answer:
disseminated intravascular coagulation (DIC)
8. A 3 year old boy who exhibits prolonged bleeding after minor trauma and a
prolonged aPTT, but a normal platelet count is likely to be diagnosed with...
, A) hemophilia
B) liver dysfunction
C) disseminated intravascular coagulation
D) thrombocytopenia - Correct Answer: hemophilia
9. Treatment for Hemophilia A includes...
A) heparin administration
B) factor IX replacement
C) factor VIII replacement
D) platelet transfusion - Correct Answer: Factor VIII replacement
10.Disseminated intravascular coagulation may be treated with heparin
therapy to...
A) enhance fibrinolysis
B) inhibit clotting factor consumption
C) activate platelets
D) enhance liver synthesis of clotting factors - Correct Answer:
inhibit clotting factor consumption
11.A deficiency of von Willebrand factor impairs...
A) activation of the coagulation cascade
B) platelet aggregation
C) platelet adhesion to injured tissue
D) platelet production - Correct Answer: platelet adhesion to injured
tissue
12.A patient is diagnosed with a tortuous blood vessel of the right hand that
bleeds spontaneously. This patient presents with...
A) petechiae
, B) purpura
C) telangiectasia
D) thrombocytosis - Correct Answer: Telangiectasia
13.A newborn has melena, bleeding from the umbilicus, and hematuria. The
newborn is most likely experiencing...
A) vitamin K deficiency bleeding
B) squired vitamin K deficiency
C) von Willebrand disease
D) disseminated intravascular coagulation - Correct Answer: Vitamin
K deficiency bleeding
14.What is involved in the release of plasminogen activators?
A) Factor X
B) Factor XII
C) HMWK
D) Kallikrein
E) Thrombin - Correct Answer: Factor XII
HMWK
Kallikrein
Thrombin
15.Which involves bleeding associated with vascular or platelet defects?
A) Bleeding that occurs immediately after trauma
B) Bleeding that involves skin or mucous membranes
C) Bleeding that is brief in duration
D) Bleeding that is delayed
E) Bleeding into muscles or joints - Correct Answer: Bleeding that
occurs immediately after trauma
Bleeding that involves skin or mucus membranes
