Pathophysiology quiz 1 Q&A {100%Success}
Pathophysiology quiz 1
Study online at https://quizlet.com/_1i1udz
1. Which type of physiological, patho is bad
changes are sup-
posed to happen
to cells: physio-
logical or patho-
logical?
2. necrosis cell death by an external injury, pathological process associated with a significant
tissue damage. Intracellular content is released and enters the bloodstream.
Location is determined by elevated levels of proteins/ enzymes (i.e. heart attack)
3. Apoptosis Cell suicide, intracellular signaling cascades, can be a normal physiological re-
sponse or pathological. Cell death pathway, enzymes degrade own cells DNA and
proteins. Can be intrinsic or extrinsic signals.
I.e. humans not having webbed hands
4. Reversible cell in- When there is reduced oxidative phosphorylation--> ATP depletion, and
jury SWELLING (think sodium potassium pump). Excess substances build up that
cause inability to perform normal metabolic functions. ACUTE injury often and can
return to normal.
5. Irreversible cell mitochondrial irreversibility, membrane has extreme defects, lysosomes come
injury and clean it up.
6. Hydrophobic Accumulation of water, arises in REVERSIBLE cell injury. Due to a malfunction
Swelling in the Na+/K+ pump! Characterized by large, pale cytoplasm, dilated/swollen
organelles. (-megaly)
7. Intercellular Ac- When they arise it causes a toxic and provoked response because it is taking up
cumulations (3 cellular space. INDICATOR, not an actual "cause."
types) 1. Excessive amount of intracellular substances
2. abnormal substances produced by cell due to faulty metabolism.
3. pigments or in organice particles unable to degrade
, Pathophysiology quiz 1 Q&A {100%Success}
Pathophysiology quiz 1
Study online at https://quizlet.com/_1i1udz
8. chaperone protein that attempts to refold degraded proteins because they take up essential
cell space.
9. ubitiquen everywhere in the body, degrades proteins so they don't take up extra space in
the cell. `
10. Atrophy decrease in cell size, loss of cell substance, dimities in function but is not dead.
Decreased protein synthesis and increased degradation.
Causes: decreased load, loss of innervation, decreased blood supply, inadequate
nutrition, persistant cell injury, aging.
ie: cast on arm
11. hypertrophy increase in cell size, results in increased organ. Increased cellular content, ONLY
BIGGER CELLS, can be physiological(i.e. working out) or pathological (i.e. heart
disease)
12. hyperplasia increase in cell number if the tissue is able to replicate. Can occur with hypertrophy
due to increase in physiological demands.
13. 3 types of hyper- demand induced (hiking), hormonal (estrogen), compensatory (removal of organ
plasia so some others grow)
14. metaplasia conversion of one cell to the another, usually because the second type of cell
tolerates the injury better. i.e. reprograming of stem cells.
15. dysplasia disorderly growth, adaptive effort gone wrong, abnormal in size and variation
could be cancerous.
16. protein degrada- 1. ubiquitin-proteosome pathway
tion pathways 2. autophagy
17. Irreversible cell
injury processes
, Pathophysiology quiz 1 Q&A {100%Success}
Pathophysiology quiz 1
Study online at https://quizlet.com/_1i1udz
1. necrosis: toxic injury, cell rupture, contents spill, inflammation.
2.apoptosis : not a dirrect kill, activates cell suicide, no rupture, no inflammation,
ingested by neighboring cells.
18. 4 types of tissue 1. coagulative necrosis
necrosis 2. liquifactive necrosis
3. fat necrosis
4. caeous necrosis
*differ in type of tissue effected
19. Coagulative Area of denatured proteins that is generally sold and the architecture remains
Necrosis constant. Most common, always the same looking. (INFART)
20. Liquefactive Dissolution of dead cells occur quickly because it is in places with no connective
Necrosis tissue (i.e. brain, bacterial infections). Lysosomal enzymes dissolve tissues. No
architecture.
21. Fat necrosis Death of adipose tissue, results from drama or pancreatitis. Visible white chalky
area. (due to degraded tissue with bile because no pancreas)
22. Caseous Necro- cheesy area of soft white dead cells that are walled off by WBC's. In the center they
sis are dead so they loose their structure (i.e. lungs)
23. Gangrene Cell death of large area of tissue, due to disruption of major blood supply.
Affects toes, legs, bowel. *usually coaglative negrosis. Can be : dry, or wet and
gaseous(death)
24. Extrinsic signals 1. Withdrawl of survival signals that suppress death pathway
of Apoptosis 2. extracellular signals, such as fat ligand, bind to cell and trigger DNA degredation
25. Intrinsic signals Cellular damage cases cells to stall growth and division. When damage is to great
of Apoptosis or mitochondrial damage (cytochrome c) then P53 governs pathway.
26. capsases proenzymes that launch a domino effect to chop DNA up.
Pathophysiology quiz 1
Study online at https://quizlet.com/_1i1udz
1. Which type of physiological, patho is bad
changes are sup-
posed to happen
to cells: physio-
logical or patho-
logical?
2. necrosis cell death by an external injury, pathological process associated with a significant
tissue damage. Intracellular content is released and enters the bloodstream.
Location is determined by elevated levels of proteins/ enzymes (i.e. heart attack)
3. Apoptosis Cell suicide, intracellular signaling cascades, can be a normal physiological re-
sponse or pathological. Cell death pathway, enzymes degrade own cells DNA and
proteins. Can be intrinsic or extrinsic signals.
I.e. humans not having webbed hands
4. Reversible cell in- When there is reduced oxidative phosphorylation--> ATP depletion, and
jury SWELLING (think sodium potassium pump). Excess substances build up that
cause inability to perform normal metabolic functions. ACUTE injury often and can
return to normal.
5. Irreversible cell mitochondrial irreversibility, membrane has extreme defects, lysosomes come
injury and clean it up.
6. Hydrophobic Accumulation of water, arises in REVERSIBLE cell injury. Due to a malfunction
Swelling in the Na+/K+ pump! Characterized by large, pale cytoplasm, dilated/swollen
organelles. (-megaly)
7. Intercellular Ac- When they arise it causes a toxic and provoked response because it is taking up
cumulations (3 cellular space. INDICATOR, not an actual "cause."
types) 1. Excessive amount of intracellular substances
2. abnormal substances produced by cell due to faulty metabolism.
3. pigments or in organice particles unable to degrade
, Pathophysiology quiz 1 Q&A {100%Success}
Pathophysiology quiz 1
Study online at https://quizlet.com/_1i1udz
8. chaperone protein that attempts to refold degraded proteins because they take up essential
cell space.
9. ubitiquen everywhere in the body, degrades proteins so they don't take up extra space in
the cell. `
10. Atrophy decrease in cell size, loss of cell substance, dimities in function but is not dead.
Decreased protein synthesis and increased degradation.
Causes: decreased load, loss of innervation, decreased blood supply, inadequate
nutrition, persistant cell injury, aging.
ie: cast on arm
11. hypertrophy increase in cell size, results in increased organ. Increased cellular content, ONLY
BIGGER CELLS, can be physiological(i.e. working out) or pathological (i.e. heart
disease)
12. hyperplasia increase in cell number if the tissue is able to replicate. Can occur with hypertrophy
due to increase in physiological demands.
13. 3 types of hyper- demand induced (hiking), hormonal (estrogen), compensatory (removal of organ
plasia so some others grow)
14. metaplasia conversion of one cell to the another, usually because the second type of cell
tolerates the injury better. i.e. reprograming of stem cells.
15. dysplasia disorderly growth, adaptive effort gone wrong, abnormal in size and variation
could be cancerous.
16. protein degrada- 1. ubiquitin-proteosome pathway
tion pathways 2. autophagy
17. Irreversible cell
injury processes
, Pathophysiology quiz 1 Q&A {100%Success}
Pathophysiology quiz 1
Study online at https://quizlet.com/_1i1udz
1. necrosis: toxic injury, cell rupture, contents spill, inflammation.
2.apoptosis : not a dirrect kill, activates cell suicide, no rupture, no inflammation,
ingested by neighboring cells.
18. 4 types of tissue 1. coagulative necrosis
necrosis 2. liquifactive necrosis
3. fat necrosis
4. caeous necrosis
*differ in type of tissue effected
19. Coagulative Area of denatured proteins that is generally sold and the architecture remains
Necrosis constant. Most common, always the same looking. (INFART)
20. Liquefactive Dissolution of dead cells occur quickly because it is in places with no connective
Necrosis tissue (i.e. brain, bacterial infections). Lysosomal enzymes dissolve tissues. No
architecture.
21. Fat necrosis Death of adipose tissue, results from drama or pancreatitis. Visible white chalky
area. (due to degraded tissue with bile because no pancreas)
22. Caseous Necro- cheesy area of soft white dead cells that are walled off by WBC's. In the center they
sis are dead so they loose their structure (i.e. lungs)
23. Gangrene Cell death of large area of tissue, due to disruption of major blood supply.
Affects toes, legs, bowel. *usually coaglative negrosis. Can be : dry, or wet and
gaseous(death)
24. Extrinsic signals 1. Withdrawl of survival signals that suppress death pathway
of Apoptosis 2. extracellular signals, such as fat ligand, bind to cell and trigger DNA degredation
25. Intrinsic signals Cellular damage cases cells to stall growth and division. When damage is to great
of Apoptosis or mitochondrial damage (cytochrome c) then P53 governs pathway.
26. capsases proenzymes that launch a domino effect to chop DNA up.
