Page 1 of 114
CARN-AP (CERTIFIED ADDICTIONS
REGISTERED NURSE – ADVANCED
PRACTICE) 2026 EXAM COMPLETE (402)
CURRENT TESTING QUESTIONS AND
DETAILED CORRECT
ANSWERS|GUARANTEED PASS.
CARN-AP
Ace your CARN-AP (Certified Addictions Registered Nurse –
Advanced Practice) Exam by mastering advanced substance use
disorders, co-occurring psychiatric conditions, and evidence-
based pharmacologic and therapeutic interventions. This
comprehensive study guide evaluates your clinical judgment
and expertise in addiction assessment, neurobiology, treatment
planning, and professional ethics through realistic, scenario-
based practice questions. It is specifically designed for nursing
career advancement in this critical specialty.
Babies born to mothers who use opioids may need
treatment with what?
, Page 2 of 114
________ can be used adjunctively to treat withdrawal
seizures. ✓ ✓ ...... ANSWER ....... morphine or
methadone
Phenobarbital
Which Neonatal withdrawal syndromes may present weeks
after birth? Name the drug. ✓ ✓ ...... ANSWER .......
Methadone
_________ is a safe and effective second-line treatment of
symptoms refractory to opioid therapy in newborns ✓ ✓
...... ANSWER ....... Clonidine
The patient must first be detoxified from opioid dependence
before starting _______
Long acting opioids, such as methadone, require at least
how many hours since last use before initiating
buprenorphine?
Short acting opioids (for example, heroin) require
approximately ____ hours since last use for sufficient
, Page 3 of 114
withdrawal to occur in order to safely initiate treatment. ✓
✓ ...... ANSWER ....... naltrexone.
48-72
12
Patients with _______ _________ syndrome often present with
abdominal pain and nausea, which may be refractory to
standard antiemetics ✓ ✓ ...... ANSWER ....... cannabis
hyperemesis
Patients with injection drug abuse are most likely to have
_____sided bacterial endocarditis.
_______ should be used empirically, which can be switched
to _______ if MRSA infection is confirmed. ✓ ✓ ......
ANSWER ....... right
Vancomycin; nafcillin
, Page 4 of 114
Marijuana use can be detected in the urine up to ___days
after exposure for infrequent users and up to ____ days for
chronic or heavy users. ✓ ✓ ...... ANSWER ....... 5
15
The _______ _______ is involved in the sense of reward from
cocaine use. ✓ ✓ ...... ANSWER ....... nucleus
accumbens
Symptomatic treatment in opioid withdrawal includes:
- ________ for diarrhea
- ______ for nausea and vomiting
- ________for myalgia ✓ ✓ ...... ANSWER .......
loperamide
promethazine
ibuprofen
Holiday heart syndrome is a syndrome caused by excessive
______ use. Excessive alcohol use results in gross and
microscopic cardiac changes leading to an atrial _______ ✓
✓ ...... ANSWER ....... alcohol
CARN-AP (CERTIFIED ADDICTIONS
REGISTERED NURSE – ADVANCED
PRACTICE) 2026 EXAM COMPLETE (402)
CURRENT TESTING QUESTIONS AND
DETAILED CORRECT
ANSWERS|GUARANTEED PASS.
CARN-AP
Ace your CARN-AP (Certified Addictions Registered Nurse –
Advanced Practice) Exam by mastering advanced substance use
disorders, co-occurring psychiatric conditions, and evidence-
based pharmacologic and therapeutic interventions. This
comprehensive study guide evaluates your clinical judgment
and expertise in addiction assessment, neurobiology, treatment
planning, and professional ethics through realistic, scenario-
based practice questions. It is specifically designed for nursing
career advancement in this critical specialty.
Babies born to mothers who use opioids may need
treatment with what?
, Page 2 of 114
________ can be used adjunctively to treat withdrawal
seizures. ✓ ✓ ...... ANSWER ....... morphine or
methadone
Phenobarbital
Which Neonatal withdrawal syndromes may present weeks
after birth? Name the drug. ✓ ✓ ...... ANSWER .......
Methadone
_________ is a safe and effective second-line treatment of
symptoms refractory to opioid therapy in newborns ✓ ✓
...... ANSWER ....... Clonidine
The patient must first be detoxified from opioid dependence
before starting _______
Long acting opioids, such as methadone, require at least
how many hours since last use before initiating
buprenorphine?
Short acting opioids (for example, heroin) require
approximately ____ hours since last use for sufficient
, Page 3 of 114
withdrawal to occur in order to safely initiate treatment. ✓
✓ ...... ANSWER ....... naltrexone.
48-72
12
Patients with _______ _________ syndrome often present with
abdominal pain and nausea, which may be refractory to
standard antiemetics ✓ ✓ ...... ANSWER ....... cannabis
hyperemesis
Patients with injection drug abuse are most likely to have
_____sided bacterial endocarditis.
_______ should be used empirically, which can be switched
to _______ if MRSA infection is confirmed. ✓ ✓ ......
ANSWER ....... right
Vancomycin; nafcillin
, Page 4 of 114
Marijuana use can be detected in the urine up to ___days
after exposure for infrequent users and up to ____ days for
chronic or heavy users. ✓ ✓ ...... ANSWER ....... 5
15
The _______ _______ is involved in the sense of reward from
cocaine use. ✓ ✓ ...... ANSWER ....... nucleus
accumbens
Symptomatic treatment in opioid withdrawal includes:
- ________ for diarrhea
- ______ for nausea and vomiting
- ________for myalgia ✓ ✓ ...... ANSWER .......
loperamide
promethazine
ibuprofen
Holiday heart syndrome is a syndrome caused by excessive
______ use. Excessive alcohol use results in gross and
microscopic cardiac changes leading to an atrial _______ ✓
✓ ...... ANSWER ....... alcohol
