(Actual Exam) – 150+
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Complete NP Board Exam
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Question 1
A 65-year-old male presents with crushing chest pain radiating to the left arm,
diaphoresis, and nausea. What is the priority initial action?
A. Administer morphine
B. Obtain a 12-lead ECG
C. Give aspirin
D. Start IV fluids
Answer: B. Obtain a 12-lead ECG
Rationale:
A 12-lead ECG within 10 minutes is critical to diagnose STEMI vs NSTEMI. While
aspirin is important, diagnosis must be confirmed rapidly to guide reperfusion
therapy.
,Question 2
A patient presents with fatigue, pallor, and spoon-shaped nails. Lab results show
microcytic anemia. What is the most likely diagnosis?
A. Vitamin B12 deficiency
B. Iron deficiency anemia
C. Aplastic anemia
D. Hemolytic anemia
Answer: B. Iron deficiency anemia
Rationale:
Microcytic anemia + koilonychia (spoon nails) strongly indicates iron deficiency.
Question 3
A 28-year-old female presents with dysuria and frequency. Urinalysis shows positive
leukocyte esterase and nitrites. What is the first-line treatment?
A. Amoxicillin
B. Ciprofloxacin
C. Nitrofurantoin
D. Doxycycline
Answer: C. Nitrofurantoin
Rationale:
First-line for uncomplicated UTI includes nitrofurantoin or TMP-SMX.
Fluoroquinolones are avoided unless complicated.
,Question 4
A patient with hypertension and diabetes should be started on which medication for
renal protection?
A. Beta-blocker
B. Calcium channel blocker
C. ACE inhibitor
D. Thiazide diuretic
Answer: C. ACE inhibitor
Rationale:
ACE inhibitors protect against diabetic nephropathy by reducing intraglomerular
pressure.
Question 5
Which condition is associated with elevated TSH and low T4?
A. Hyperthyroidism
B. Subclinical hypothyroidism
C. Primary hypothyroidism
D. Secondary hypothyroidism
Answer: C. Primary hypothyroidism
Rationale:
High TSH + low T4 = thyroid gland failure (primary hypothyroidism).
Question 6
, A 4-year-old child presents with a barking cough and inspiratory stridor. What is the
most likely diagnosis?
A. Epiglottitis
B. Croup
C. Asthma
D. Bronchiolitis
Answer: B. Croup
Rationale:
Classic signs: barking cough + stridor, usually viral.
Question 7
A patient has a fasting glucose of 130 mg/dL on two occasions. What is the
diagnosis?
A. Prediabetes
B. Type 2 Diabetes Mellitus
C. Impaired glucose tolerance
D. Normal
Answer: B. Type 2 Diabetes Mellitus
Rationale:
Fasting glucose ≥126 mg/dL on two occasions = diabetes.
Question 8
Which medication is contraindicated in pregnancy?