Exam Prep Guide 2026/2027
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Helminths -ANSWER✅✅✅Parasites that typically live inside a host. They feed on
nutrients within the host and reproduce which often leads to chronic infections. Have
complex life cycles
Helminths Modes of Transmission -ANSWER✅✅✅Ingestion of eggs or larvae, skin
penetration, vector transmission and consumption of infected Intermediate hosts.
Helminth Disease pathogenesis and clinical effects -ANSWER✅✅✅Nutrient depletion,
tissue damage and inflammation, immune evasion and chronic infection and mechanical
blockage.
Helminth Diagnosis -ANSWER✅✅✅Microscopic examination, serological tests and
molecular tests (PCR).
Platyhelminthes -ANSWER✅✅✅Bilateral symmetrical dorsoventrally flattened
acoelomate. Have ectoderm, mesoderm and endoderm and lack a body cavity
(coelem). Exhibit cephalization and a ladder-like nervous system. They have ciliated
feeding tentacles and no specialized circulatory system or respiratory system which
means they rely on diffusion for gas exchange. Most have mouth and gut.
Osmoregulatory system which regulates water content and eliminate waste. Theyre
hermaphroditic.
Flame Cells -ANSWER✅✅✅Function as primitive kidneys. Flame cell is a specialized
excretory cells located at ends of branched tubules. Resembles a "flickering flame"
under microscope and have tuft of cilia inside. Beating of cilia creates a "current",
drawing fluid into flame cell and filtrates.
Excretory Tubules -ANSWER✅✅✅Flame cells connect to system of branching tubules
that run through body. Tubules merge into larger collecting ducts which eventually open
to outside via nephridoiopores. Tubules allow for selective reabsorption of useful
substances before expelling waste.
Free-Living Platyhelminthes (Planaria) -ANSWER✅✅✅Extensive flame cell networks
and high need for osmoregulation in freshwater environment.
Parasitic Platyhelminthes (Trematodes/Cestodes) -ANSWER✅✅✅Flame cells less
developed and live in osmotically stable environments (host intestines or blood).
, Rhabditophora -ANSWER✅✅✅Includes Neodermata (monophyletic group). This is
where the major of parasitic flatworms found. Lost a ciliated epithelium in most life cycle
stages and instead enveloped in their parasitic phases in a syncytial tegument called
the neodermis.
Neodermis -ANSWER✅✅✅Specialized outer covering for adaptation to help survive in
host's body, providing protection against immune responses and facilitating nutrient
absorption. Structure is syncytial tegument, microtriches and glycocalyx layer which
protects parasite from host digestive enzymes and immune attacks.
Aspidogastrea -ANSWER✅✅✅It parasitizes freshwater and marine mollusks.
Cartilaginous fish or bony fish and turtles serve as either facultative or obligatory hosts.
They also have a large ventral disc.
Digenea -ANSWER✅✅✅Live under scales of some fish species. They have complex
life cycles. Involves a mollusc as intermediate host and a vertebrate as definitive host.
Exhibit alternation of asexual and sexual generation. Adults usually hermaphroditic and
have oral and ventral suckers and most inhabit intestines as adults.
Schistosoma spp -ANSWER✅✅✅Parasitic trematodes (blood flukes) that cause
schistosomiasis. Schistosoma species are dioecious. Infection occurs through skin
penetration by cercariae and adult worms reside in venous system. Males shorter and
thicker with gynecophoric canal and females are longer and slender.
Schistosoma spp Eggs -ANSWER✅✅✅S.haematobium (Terminal spine) is found in
urine. S.mansoni (Lateral spine) is found in stool. S. japonicum (Small, inconspicuous
spine) is found in stool.
Schistosoma spp General Life Cycle -ANSWER✅✅✅Indirect cycle involving a snail
intermediate host. Eggs excreted in urine (S. heamatobium) or feces (S. mansoni, S.
japonicum). Miracidium hatches in freshwater and infects specific snail species and
parasite develops through sporocysts and produces cecariae (infective stage).
Cercariae is released into water and penetrates human skin and enter blood vessels,
migrates through lungs and heart and sets up in liver and mature into adult worms in the
mesenteric or pelvic venous system. Adult worms produce eggs, which migrate to
bladder or intestines and are excreted continuing the cycle.
Schistosoma mansoni -ANSWER✅✅✅Adults live in copula (sexual union) in blood
vessels. Causes of human intestinal and hepatosplenicschistosomiasis AKA bilharzia or
snail fever. Definitive host is primarily humans, primates, rodents. Intermediate host is
freshwater pulmonated snails.
Schistosoma mansoni Transmission -ANSWER✅✅✅Lateral-spined egg is passed in
feces and into water. Eggs hatch to release miracidia which infect intermediate host.
Cercariae are released from snail, swim in water and then penetrate human skin.