Which of the following would be TRUE if the oxygen-hemoglobin dissociation curve is shifted to
the right?
Partial pressure of oxygen is decreased
Partial pressure of carbon dioxide is increased
pH is increased
Temperature is decreased - correct answer ✔✔Partial pressure of carbon dioxide is increased
With an increase in 2,3 DPG:
Capillary permeability will increase and the patient will begin bleeding
The patient will begin to develop ARDS
Hemoglobin less readily releases oxygen molecules
Hemoglobin more readily releases oxygen molecules - correct answer ✔✔Hemoglobin more
readily releases oxygen molecules
A 45 year old man was brought to ER after he was found nearly unconscious in his garage with
his automobile running. How will this effect his oxyhemoglobin disassociation curve?
,Right
No change
Up
Down - correct answer ✔✔Down
According to the oxyhemoglobin disassociation curve, if a patient has an oxygen saturation of
90% what is the corresponding PaO2? Assuming patient does not have any shift.
80
60
90
70 - correct answer ✔✔60
Increased oxygen extraction of anemic blood by the tissues produces increased concentrations
of deoxyhemoglobin in the RBC's which stimulates the production of 2,3 DPG. Which direction
would the sigmoidal curve shift?
Right and downward
Left and downward
,Left and upward
Upward - correct answer ✔✔Right and downward
The oxyhemoglobin disassociation curve suggests: (I'm challenging you to apply what we
learned. Carefully analyze each response and the correct answer will appear)
Low PaO2 with low oxygen saturation readings
Oxygen saturation probes don't work on people with infections because the increase in capillary
permeability distorts the infrared light usually absorbed by the hemoglobin.
We should no longer use SaO2 technology and implement EtCO2 and capnography instead.
A septic patient will have hypoxic tissues with high oxygen saturation readings - correct answer
✔✔A septic patient will have hypoxic tissues with high oxygen saturation readings
Which of the following will not cause the oxygen-hemoglobin dissociation curve to shift to the
right?
increased CO
increased CO2
increased H+
increased temperature - correct answer ✔✔increased CO
, You arrive at a small outlying facility to transport a patient who was found unconscious in a
structure fire and subsequently treated and transported by EMS. The patient is now intubated
and when you arrive to transport the pattient you see the following values on the lab report:
pH 7.25PaO2 91PaCO2 64Bicarb 18
What does this patient's ABG indicate?
A right shift on the oxyhemoglobin disassociation curve.
A compensated metabolic alkalosis
A left shift on the oxyhemoglobin disassociation curve.
The inhalation of smoke containing high levels of 2,3 DPG - correct answer ✔✔A right shift on
the oxyhemoglobin disassociation curve.
A 67-year-old male is brought in by EMS after being found unconscious on the first floor of a
burning building. On exam, his respiratory rate is 14 breaths/min with scattered wheezes. He
has no evidence of any burns, but dark soot is caked around much of his face. Suspecting
inhalational injury, you expect this man's oxygen-hemoglobin curve will be
Up
Right
No change
Left - correct answer ✔✔Left