WITH OVER 165 EXAM
QUESTIONS AND CORRECT
ANSWERS
Define Polycystic ovary syndrome (PCOS)
A symptom complex associated with menstrual irregularity due to oligo-
ovulation or anovulation and clinical or biochemical signs of
hyperandrogenism
Women with PCOS are at risk for future development of what?
-Endometrial cancer
-Diabetes mellitus
-Heart disease
PCOS (symptoms)
-Irregular menses or amenorrhea
-Infertility
-Hirsutism
-Other signs of androgen excess (acne, deep voice, male pattern baldness)
PCOS (possible physical findings)
-Enlarged ovaries (50% of the time)
,-Abdominal obesity (>35 inches)
-Acanthosis nigricans & skin tags (usually around neck)
-Acne
-Virilization
^hirsutism, deep voice, frontal balding, increased muscle mass, enlargement
of clitoris, and decreased breast size
Rotterdam criteria for diagnosis of PCOS
At least 2 of the following in adult females:
-Oligo/anovulation
-Clinical/biochemical hyperandrogenism
-Polycystic ovaries
^all 3 present in adolescent female
PCOS- labs
-Pregnancy test
-Prolactin
-TSH level
-Testosterone
-Glucose & lipid levels
-Serum 17-hydroxyprogesterone (17-OHP) --> greater than 800 ng/dL with
PCOS
,-Endometrial biopsy (rule out hyperplasia)
-Ultrasound of ovaries
PCOS- management
-Low dose combined hormonal contraception
-Progestin-only contraception
If patient does not desire & is not at risk for pregnancy, and does not want to
use hormonal contraception, focus on prevention of endometrial hyperplasia
via what?
-Endometrial biopsy
-Medroxyprogesterone acetate for 10 days of month induces withdrawal
bleeding
Cervical cancer screening recommendations
Pap smear alone every 3 years (21-65 years old)
OR
Pap smear + HPV test every 5 years (30-65 years old)
Cervical cancer screening for women with history of CIN2 or a more serious
diagnosis?
Should continue routine screening for at least 20 years after spontaneous
regression or treatment
, Colorectal cancer screening recommendations
Beginning at age 45-50 till 75
-guaiac fecal occult blood test (yearly) OR stool DNA tests (every 3 years)
OR
-colonoscopy every 10 years
Breast cancer screening recommendations
Beginning at age 40-50
Can stop at 74 years old
Mammograms every 1-2 years
Diabetes screening recommendations
Every 3 years starting at age 45
Herpes zoster vaccine
2 doses of recombinant zoster vaccine (RZV) 2-6 months apart for adults
aged 50 or older
^regardless of past episode of herpes zoster or receipt of zoster vaccine live
(ZVL) (Zostavax)