BIOL252 Human Anatomy & Physiology II with Lab
Module 9 Exam Actual Exam 2026/2027 – Complete
Exam-Style Questions with Detailed Rationales | 100%
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Male Reproductive System: Anatomy & Spermatogenesis
Q1: Looking at the microscopic structure of the testes, which specific cell type is located
between the seminiferous tubules and is responsible for producing testosterone in response to
luteinizing hormone (LH) stimulation?
A. Spermatogonia
B. Sertoli cell
C. Leydig cell [CORRECT]
D. Peritubular cell
Correct Answer: C
Rationale: The Leydig cells are found in the connective tissue interstitium between the tubules.
When LH hits its receptors, these cells convert cholesterol into testosterone, which is vital for
sperm production and male characteristics.
Q2: During spermatogenesis, developing sperm cells need to be protected from the body’s
immune system. Which specific cell located in the walls of the seminiferous tubules forms the
blood-testis barrier and provides nutrients to the growing germ cells?
A. Leydig cell
B. Myoid cell
C. Sertoli cell [CORRECT]
D. Spermatid
Correct Answer: C
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Rationale: Sertoli cells nurse the developing spermatids and create the blood-testis barrier,
keeping the immune system from attacking the haploid sperm cells since they are genetically
different.
Q3: Let's trace the life cycle of a sperm. What is the correct sequence of development starting
from the diploid stem cell?
A. Spermatid → Secondary Spermatocyte → Primary Spermatocyte → Spermatozoa
B. Spermatogonia → Primary Spermatocyte → Secondary Spermatocyte → Spermatid →
Spermatozoa [CORRECT]
C. Spermatid → Primary Spermatocyte → Spermatogonia → Spermatozoa
D. Primary Spermatocyte → Spermatozoa → Spermatid
Correct Answer: B
Rationale: The process begins with spermatogonia (diploid stem cells), which grow into primary
spermatocytes (which undergo meiosis I). They then become secondary spermatocytes (which
undergo meiosis II), then mature into spermatids, and finally transform into spermatozoa.
Q4: A male patient is concerned about fertility. If we look at the timeframe for sperm production,
approximately how long does it take from the time a spermatogonia enters meiosis until a mature
spermatozoa is released?
A. 24 hours
B. 7 to 10 days
C. About 64 to 72 days [CORRECT]
D. 6 months
Correct Answer: C
Rationale: Spermatogenesis isn't instant; it takes roughly 64 to 72 days for a single sperm to fully
develop. This is why lifestyle changes like quitting smoking or drinking can take a few months
to show improvement in sperm quality.
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Q5: After sperm leave the testes, they aren't ready for ejaculation yet. Where do they go to finish
maturing and gain their ability to swim?
A. Prostate gland
B. Seminal vesicle
C. Epididymis [CORRECT]
D. Urethra
Correct Answer: C
Rationale: Sperm are essentially immobile when they leave the testes. They travel to the
epididymis, where they gain motility and the ability to fertilize an egg, and are stored there until
ejaculation.
Q6: When a male ejaculates, sperm travel through a duct system. Which specific duct connects
the epididymis to the ejaculatory duct, running through the inguinal canal?
A. Urethra
B. Ductus deferens (Vas deferens) [CORRECT]
C. Seminal vesicle duct
D. Bulbourethral duct
Correct Answer: B
Rationale: The ductus deferens, or vas deferens, acts as the transport highway moving sperm
from storage in the epididymis up into the pelvic cavity to join the urethra.
Q7: During a vasectomy, a surgeon cuts the vas deferens. How does this affect the reproductive
system?
A. It stops the production of testosterone.
B. It prevents sperm from reaching the urethra to be ejaculated. [CORRECT]
C. It stops the production of seminal fluid.
D. It immediately causes sterility.