NSG 6005 Week 2 Pharm Quiz_Fall 2020_100% Correct Answers | NSG6005 Week 2 Pharm Quiz_Fall 2020_Graded A

NSG 6005 Week 2 Pharm Quiz_Fall 2020 – South University Savannah Chapter 2: Review of Basic Principles of Pharmacology ____ 1. A patient’s nutritional intake and lab work reflects hypoalbuminemia. This is critical to prescribing because: A. Distribution of drugs to target tissue may be affected ____ 2. Drugs that have a significant first-pass effect: C. Are rapidly metabolized by the liver and may have little if any desired action ____ 3. The route of excretion of a volatile drug will likely be: B. The lungs ____ 4. Medroxyprogesterone (Depo Provera) is prescribed IM to create a storage reservoir of the drug. Storage reservoirs: C. Increase the length of time a drug is available and active ____ 5. The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s: B. Biological half-life ____ 6. Azithromycin dosing requires the first day’s dose be twice those of the other 4 days of the prescription. This is considered a loading dose. A loading dose: A. Rapidly achieves drug levels in the therapeutic range ____ 7. The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the: C. Onset of action ____ 8. Phenytoin requires a trough level be drawn. Peak and trough levels are done: D. To determine if a drug is in the therapeutic range ____ 9. A laboratory result indicates the peak level for a drug is above the minimum toxic concentration. This means that the: B. Concentration will produce an adverse response ____ 10. Drugs that are receptor agonists may demonstrate what property? C. Desensitization or down-regulation with continuous use ____ 11. Drugs that are receptor antagonists, such as beta blockers, may cause: B. An exaggerated response if abruptly discontinued ____ 12. Factors that affect gastric drug absorption include: C. Lipid solubility of the drug ____ 13. Drugs administered via intravenous (IV) route: B. Begin distribution into the body immediately ____ 14. When a medication is added to a regimen for a synergistic effect, the combined effect of the drugs is: B. Greater than the sum of the effects of each drug individually ____ 15. Which of the following statements about bioavailability is true? A. Bioavailability issues are especially important for drugs with narrow therapeutic ranges or sustained release mechanisms. ____ 16. Which of the following statements about the major distribution barriers (blood-brain or fetal placental) is true? B. The blood-brain barrier slows the entry of many drugs into and from brain cells. ____ 17. Drugs are metabolized mainly by the liver via Phase I or Phase II reactions. The purpose of both of these types of reactions is to: C. Change drug molecules to a form that an excretory organ can excrete ____ 18. Once they have been metabolized by the liver, the metabolites may be: A. More active than the parent drug B. Less active than the parent drug C. Totally “deactivated” so that they are excreted without any effect D. All of the above ____ 19. All drugs continue to act in the body until they are changed or excreted. The ability of the body to excrete drugs via the renal system would be increased by: D. Unbinding a nonvolatile drug from plasma proteins ____ 20. Steady state is: B. When the amount of drug in the body remains constant ____ 21. Two different pain meds are given together for pain relief. The drug-drug interaction is: D. Additive ____ 22. Actions taken to reduce drug-drug interaction problems include all of the following EXCEPT: - - -