CWS 1 REVIEW SHEET 2026 FULL
QUESTIONS AND ACCURATE
ANSWERS
◉ What are the layers of the epidermis from most superficial to most
deep? Answer: Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale (germinativa)
◉ What are the layers of the dermis from most superficial to most deep?
Answer: Papillary dermis
Reticular dermis
◉ What is/are the primary cell type(s) of the stratum spinosum? Answer:
Langerhan's cells
◉ What is/are the primary cell type(s) of the stratum basale? Answer:
Keratinocytes, Melanocytes, Merkel cells
◉ What is/are the primary cell type(s) of the stratum granulosum?
Answer: Corneocytes (terminally differentiated keratinocytes)
,◉ What is/are the primary cell type(s) of the stratum corneum? Answer:
Dead keratinocytes
◉ What is/are the primary cell type(s) of the dermis? Answer:
Fibroblasts, Mast cells, Macrophages, Lymphocytes
◉ Tissue loss includes only the epidermis. Answer: Superficial
◉ Tissue loss includes the epidermis and part of the dermis. Answer:
Partial thickness
◉ Tissue loss includes the epidermis and all of the dermis. Answer: Full
thickness
◉ Tissue loss includes subcutaneous tissues. Answer: Subdermal
◉ When does hemostasis or coagulation occur during the stages of
healing? Answer: Immediately after tissue injury
◉ When does inflammation occur during the stages of healing? Answer:
0-4 days
◉ When does proliferation occur during the stages of healing? Answer:
4-21 days
,◉ How long can remodeling last? Answer: Up to 2 years
◉ What are the key cells of hemostasis? Answer: Platelets
◉ What are the key cells of inflammation? Answer: Neutrophils,
Macrophages
◉ What are the key cells of proliferation? Answer: Fibroblasts,
Epithelial cells, Endothelial cells, Macrophages
◉ What are the key cells of remodeling? Answer: Fibroblasts
◉ What produces PDGF? Answer: Platelets and macrophages
◉ What stimulates fibroblasts? Answer: Platelet Derived Growth Factor
◉ What is an integrin? Answer: A cell surface receptor that enables cells
to interact with components of the ECM
◉ What secretes MMPs and TIMPs? Answer: Keratinocytes and
fibroblasts
◉ What regulates the activity of MMPs? Answer: TIMPs
, ◉ Fibroblasts play a key role in the extracellular matrix deposition of
which types of proteins? Answer: Collagen
Elastin
Reticulin
Proteoglycans
Glycosaminoglycans
◉ Myofibroblasts secrete which type of collagen? Answer: Type I
◉ Which type of collagen is primarily found in uninjured tissue?
Answer: Type I
◉ Which type of collagen is primarily found in wounds in the
proliferative phase of wound healing? Answer: Type III
◉ What is the transitional marker between the inflammatory and
proliferative phases of healing? Answer: Macrophage migration into the
wound site
◉ Which cells are the last to arrive during the proliferative phase?
Answer: T lymphocytes
◉ What are the three types of T lymphocytes and what are their
functions? Answer: 1. Cytotoxic T cells = directly target and kill any
antigen-bearing cells
QUESTIONS AND ACCURATE
ANSWERS
◉ What are the layers of the epidermis from most superficial to most
deep? Answer: Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale (germinativa)
◉ What are the layers of the dermis from most superficial to most deep?
Answer: Papillary dermis
Reticular dermis
◉ What is/are the primary cell type(s) of the stratum spinosum? Answer:
Langerhan's cells
◉ What is/are the primary cell type(s) of the stratum basale? Answer:
Keratinocytes, Melanocytes, Merkel cells
◉ What is/are the primary cell type(s) of the stratum granulosum?
Answer: Corneocytes (terminally differentiated keratinocytes)
,◉ What is/are the primary cell type(s) of the stratum corneum? Answer:
Dead keratinocytes
◉ What is/are the primary cell type(s) of the dermis? Answer:
Fibroblasts, Mast cells, Macrophages, Lymphocytes
◉ Tissue loss includes only the epidermis. Answer: Superficial
◉ Tissue loss includes the epidermis and part of the dermis. Answer:
Partial thickness
◉ Tissue loss includes the epidermis and all of the dermis. Answer: Full
thickness
◉ Tissue loss includes subcutaneous tissues. Answer: Subdermal
◉ When does hemostasis or coagulation occur during the stages of
healing? Answer: Immediately after tissue injury
◉ When does inflammation occur during the stages of healing? Answer:
0-4 days
◉ When does proliferation occur during the stages of healing? Answer:
4-21 days
,◉ How long can remodeling last? Answer: Up to 2 years
◉ What are the key cells of hemostasis? Answer: Platelets
◉ What are the key cells of inflammation? Answer: Neutrophils,
Macrophages
◉ What are the key cells of proliferation? Answer: Fibroblasts,
Epithelial cells, Endothelial cells, Macrophages
◉ What are the key cells of remodeling? Answer: Fibroblasts
◉ What produces PDGF? Answer: Platelets and macrophages
◉ What stimulates fibroblasts? Answer: Platelet Derived Growth Factor
◉ What is an integrin? Answer: A cell surface receptor that enables cells
to interact with components of the ECM
◉ What secretes MMPs and TIMPs? Answer: Keratinocytes and
fibroblasts
◉ What regulates the activity of MMPs? Answer: TIMPs
, ◉ Fibroblasts play a key role in the extracellular matrix deposition of
which types of proteins? Answer: Collagen
Elastin
Reticulin
Proteoglycans
Glycosaminoglycans
◉ Myofibroblasts secrete which type of collagen? Answer: Type I
◉ Which type of collagen is primarily found in uninjured tissue?
Answer: Type I
◉ Which type of collagen is primarily found in wounds in the
proliferative phase of wound healing? Answer: Type III
◉ What is the transitional marker between the inflammatory and
proliferative phases of healing? Answer: Macrophage migration into the
wound site
◉ Which cells are the last to arrive during the proliferative phase?
Answer: T lymphocytes
◉ What are the three types of T lymphocytes and what are their
functions? Answer: 1. Cytotoxic T cells = directly target and kill any
antigen-bearing cells
