NBME 9 Comprehensive Exam
(2026/2027) – Questions and Revised
Answers Latest Update Study Guide||
GUARANTEED PASS
Who should receive PCV13 vaccine? -CORRECTANSWER Patients with HIV,
lymphoma, leukemia, multiple myeloma, functional or anatomic asplenia, ESRD,
cochlear implants, CSF leaks, hx solid organ transplant, immunodeficiencies
Post-transplant lymphoproliferative disorder -CORRECTANSWER EBV (monoclonal B
lymphocytes)
Type of cells increased in multiple myeloma -CORRECTANSWER B cells (monoclonal
spike) -- multiple myeloma is a disorder of plasma cell proliferation; plasma cells are
terminally differentiated B cells, thus it is considered a B-lymphocyte malignancy
Alk phos levels in hemolysis -CORRECTANSWER Normal (alk phos is elevated in the
case of biliary obstruction -- hemolysis occurs before this point)
Medication options for acute depression in a patient with bipolar -CORRECTANSWER
Lithium, lamotrigine, quetiapine, lurasidone
, How to diagnose botulism -CORRECTANSWER Repetitive nerve stimulation studies
(electromyography) --> improves with repeated stimulation
Prevention of stroke in a patient with a fib -CORRECTANSWER Warfarin
(anticoagulation)
Vestibular neuronitis -CORRECTANSWER Inflammation of vestibular portion of cranial
nerve VIII - commonly after viral infection
Acute vertigo, nausea, vomiting, nystagmus (horizontal or rotary), gait instability --
episodic!
Basilar migraine -CORRECTANSWER Begins with brainstem aura symptoms - vertigo,
incoordination, tinnitus, hearing loss, diplopia, dysarthria
Symptoms last only a few minutes to an hour and are followed by headache (occipital)
Treatment of diaper candidiasis -CORRECTANSWER Topical nystatin
JIA - female child with oligoarthritis and positive ANA titers; what should you evaluation
-CORRECTANSWER Slit-lamp evaluation (uveitis is common and often asymptomatic
until it has led to complications)
(2026/2027) – Questions and Revised
Answers Latest Update Study Guide||
GUARANTEED PASS
Who should receive PCV13 vaccine? -CORRECTANSWER Patients with HIV,
lymphoma, leukemia, multiple myeloma, functional or anatomic asplenia, ESRD,
cochlear implants, CSF leaks, hx solid organ transplant, immunodeficiencies
Post-transplant lymphoproliferative disorder -CORRECTANSWER EBV (monoclonal B
lymphocytes)
Type of cells increased in multiple myeloma -CORRECTANSWER B cells (monoclonal
spike) -- multiple myeloma is a disorder of plasma cell proliferation; plasma cells are
terminally differentiated B cells, thus it is considered a B-lymphocyte malignancy
Alk phos levels in hemolysis -CORRECTANSWER Normal (alk phos is elevated in the
case of biliary obstruction -- hemolysis occurs before this point)
Medication options for acute depression in a patient with bipolar -CORRECTANSWER
Lithium, lamotrigine, quetiapine, lurasidone
, How to diagnose botulism -CORRECTANSWER Repetitive nerve stimulation studies
(electromyography) --> improves with repeated stimulation
Prevention of stroke in a patient with a fib -CORRECTANSWER Warfarin
(anticoagulation)
Vestibular neuronitis -CORRECTANSWER Inflammation of vestibular portion of cranial
nerve VIII - commonly after viral infection
Acute vertigo, nausea, vomiting, nystagmus (horizontal or rotary), gait instability --
episodic!
Basilar migraine -CORRECTANSWER Begins with brainstem aura symptoms - vertigo,
incoordination, tinnitus, hearing loss, diplopia, dysarthria
Symptoms last only a few minutes to an hour and are followed by headache (occipital)
Treatment of diaper candidiasis -CORRECTANSWER Topical nystatin
JIA - female child with oligoarthritis and positive ANA titers; what should you evaluation
-CORRECTANSWER Slit-lamp evaluation (uveitis is common and often asymptomatic
until it has led to complications)
